I am in 3rd week of my Epclusa treatment and only small symptoms nothing major except insomnia. Very difficult to go to sleep. I started smoking marijuana at night which helps me out alot to go to sleep. My question is if is it ok for me to smoke Marijuana during treatment. Does Marijuana interfere with Epclusa and my final result to achieve SVR. Thanks.
We currently have very little data regarding possible drug interactions associated with marijuana use; however, based on our knowledge of the metabolism of the major cannabinoids it contains, we can theorize about possible interactions not yet studied. Side effects can be observed with agents such as cytochrome of all kinds. As for using Epclusa with marijuana, having personally tried it, I can say that there is no change. I buy medical marijuana from an old friend who has built a business on it. As I understand it, you can use it with the
platform, the purpose of which is to track the movement of cannabis products and related financial activity.
While we can hypothesise about the impact of Marijuana on the Hep C drugs I would estimate in excess of 20% of my patients used it while on treatment and their success rates were similar to non smokers.
Veterans Affairs in the USA have also found similarly (although > 50% had a substance abuse problem)