People report having few side effects with epclusa.
It is very important, however, to drink lots of water to avoid dehydration and to take pills at one time of the day. Lots of water is a must with velpatasvir due to its taste and so as to compensate for the dehydration that cases the side effects (light headaches, fatigue).
Just a caution about dehydration.
VL pre treatment 29000 ME/ml
AST 32 ALT 94, F0
Started treatment 13 January 2017
Generic sofosbuvir/velpatasvir (Incepta)
VL 9 days into treatment <300 (undetected)
AST 13.8 ALT 22
Side effects: mild dehydration, not a problem at all if I drink water at night, nothing to worry about
Diet and gastric ph are very important with velpatasvir. One must think what and when to eat to keep gastric pH low. Side effects disappeared 2 weeks after, unless I ate anything < 4hrs before the pill. SVR60.