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TOPIC: 2b Juen started dac.sof 9.4.16 hcvl rna 9.5 .16 says undetected

2b Juen started dac.sof 9.4.16 hcvl rna 9.5 .16 says undetected 2 years 8 months ago #15986

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Hello everybody! From Juen , 2b geno

Here is an update on my treatment.
Started the dac/solvadi meds 9.4.16, -a month ago. Hep c 20 years +

Hep c quantitation rna 31.3.16 was units iu/ml 1,420,000-Hep c log 10 value, units log 10=6.5
15.3.16 ast 67, alt was 89


According to tests this month 9.5.16-
Pathology Qualitative estimation of HCVL RNA( viral load ) reads -'Not detected'
And Ast 25 Alt 17

So this is a good result I think /I hope!-with 8 weeks to go -finger crossed it , -the hep c , will disappear from my system forever!

Side effects are minimum ,- compared to what I imagined.

Insomnia, weakness, are the main, (had fatique , weakness before treament ) , I try and give the meds their best chance , so keep my diet healthy , for me means drinking lots fresh water, plenty of veg, fruit and excercise moderately daily , swimming /'water therapy' is easiest to cope when tired!

Again I am so thankful to gp2u and hep c club for being here to help , by giving us great info , alternatives to often expensive and extremely conservative medical systems , -i.e drug treatment /$ choice , and great social support given by the forum folks!

I will update in a month again !
Best regards to all
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Last Edit: 2 years 8 months ago by Juen. Reason: Adding attachment
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2b Juen started dac.sof 9.4.16 hcvl rna 9.5 .16 says undetected 2 years 8 months ago #15988

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Hello Juen,

Yes this is the expected result. The rest of the treatment should kill off the last few stragglers. BMS got 49/52 for SOF+DCV in GT2 so it is a good choice and avoids the ribavirin.

At the moment we have 100% so please don't ruin the average! :-)
YMMV
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2b Juen started dac.sof 9.4.16 hcvl rna 9.5 .16 says undetected 2 years 8 months ago #16034

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Hi Juen,

Great to see those good results. It sounds like you are doing everything right and reaping the rewards. Looking forward to seeing your next lot of results. Keep well. Coral
G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24...
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2b Juen started dac.sof 9.4.16 hcvl rna 9.5 .16 says undetected 2 years 8 months ago #16051

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Great post Juen … and brilliant results!

I’m on the same path as you … one day behind … still waiting for VL.

I too exercise every morning before taking the meds … I find that it sets me up for the day … I feel great afterwards and it ensures that I’m fully hydrated at the start of the day (I wake up with a dry mouth half the time).

Keep up the good work , and I look forward to seeing your SVR.

Cheers GT2
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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2b Juen started dac.sof 9.4.16 hcvl rna 9.5 .16 says undetected 2 years 8 months ago #16053

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looking good Juen, you're giving it the best shot and can't lose imo. cheers and all the best to you. :)
reg nurse and wife of:
genotype 3 (probably since '75), f4, cirrhosis, Tx naive
Oct '15 - Dx hcc
Pre Tx -- VL: 330,000......, AST 202, ALT 137, Bil 24, ALB 30
04/11/15 -Sof & Dac
30/11/15 -VL: 80................, AST 28, ALT 18, Bil 12, ALB 32
06/01/16.-VL: not detected, AST 29, ALT 16, Bil 13, ALB 34
01/02/16 -VL: not detected, AST 28, ALT 16, Bil 13, ALB 36


.
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2b Juen started dac.sof 9.4.16 hcvl rna 9.5 .16 says undetected 2 years 8 months ago #16057

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Good to hear. I am sure you've got this nailed
I take my meds just before bed, so they can do their work while I'm lying around not doing anything. In the morning I swim in the ocean or go to a Yoga class
Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
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