Hello Everyone ! I was recently diagnosed with GT3 (Age - 48, VL 365,495 Fscan 18.2 Kpa) . Got it in the nineties. On sofosbuvir+daclatasvir right now. No outward symptoms at all. No other conditions except hypertension having telmisartan 40 everyday. I have a question regarding another drug that I occasionally take i.e. sildenafil citrate (viagra) . Does this drug have any contraindications ? Could someone please reply.
Hello Paul, and welcome to the forum . The University of Liverpool in the UK has a dedicated page for checking interactions between the new Hepatitis C medications (DAAs) and other common medications, and when I checked the 'Sofosbuvir + Daclatasvir' combo and 'Sildenafil', the result was 'No Interaction Expected'. You can take a look here www.hep-druginteractions.org/checker
Thanks Dr James, Mar. As I have mentioned my fscan score is 18.2 kpa which is cirrhosis. But I do not have any noticeable symptoms at all. Is it normal not to have any symptoms even with a fscan score of 18.2?
Hello everyone, after 4 weeks of sof/dac regime my VL is undetected. The doc never prescribed riba. He has said that he may discontinue meds after 8 weeks. I am worried. Is there a possibility of a relapse in future if the recommended 12 weeks is not adhered to?
As I go to a government facility where the meds are given free, I do not have a say in the treatment.
Hi Paul, if you're in India, then you should have access to relatively cheap generic HCV medications, and you can ask you doctor where to source 100% authentic high quality generic medications there. I would urge you to follow Dr James's recommendation of completing 24 weeks of Sof/Dac and Ribavirin instead of the just 8 weeks of Sof/Dac that you may be treated with as that will almost certainly lead to relapse.
It has been a little over nine months since the time I underwent a 3 months treatment at a local Community Health Centre. I was on a Sof + Dac regimen for 12 weeks. The doctor advised HCV RNA test a week ago. Virus was not detected. He has not prescribed any other tests and asked me to come back after six months.
Apart from a LFT what are the tests that are normally done after treatment?
In terms of other tests, it depends on how sick a patient is and what has been done previously.
So, say I treat a patient who is not cirrhotic and relatively well and 4 weeks into treatment their LFTs are normal and PCR negative. I would not do any more tests until SVR12 and then just do a PCR and LFTs.
At the other end of the spectrum a patient with cirrhosis who was taking ribavirin would get a CBC and CMP (FBC, UEC, LFT) every 2 weeks during treatment and lots of follow up testing including AFP and ultrasound to check for HCC.
Other tests just depend on the patient and their problems.