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Laxatives 6 years 5 months ago #25674

  • catemae
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  • Genotype 1a, Onset 2012, F0, Treatment Naive
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Just wondering if there are any laxatives safe for use with ledipasvir + sofosbuvir? Having bowel issues due to my menstrual cycle and need some relief.

Laxatives 6 years 5 months ago #25676

  • DrJames
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Yes, you can.

I prefer lactulose (a non-absorbable sugar) because you can "dial a dose"

10 ml twice a day, 20 ml, or even 30 ml depending on how much help is required. Soft, but not runny is the desired outcome.

I would probably have it separate by an hour or two to the Harvoni just to remove the worry of any interaction. So if you morning dose, have your tablets, then some lactulose at 10 am and then before bed at circa 10 pm.
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Laxatives 6 years 5 months ago #25780

Hi Catemae
For a bit of choice, I use physillium hulls powder. Its good at either getting things moving as well as slowing things down if you have the squirts. Best of all its real cheap when bought in bulk. Very effective and super easy on the system too . Like the Doc says, have it a few hrs after meds as you dont want any of your meds transported out. just stir in a tsp in a glass of water and wait just until it gets thick and slippery then chase it with another glass of water .
G2 non A non B
Diagnosed 2002 biopsy grade1,stage1
LFT 2002 2004 2011 2015 2016 2017
AST 76 69 34 46 45 64
Alt 185 175 67 103 84 129

2017 VL 1,600 000
march 1 4 week tx VL undetected
AST 18, ALT 15

8 week qualitative undetected
The following user(s) said Thank You: DrJames, Mnem, Mar
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