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Good News for Cirrhotic Patients 7 years 6 months ago #3160

klhilde Topic Author Offline Elite Member Posts: 253 Karma: 6 Thank you received: 498	www.empr.com/aasld-2015/sofosbuvir-based...osis/article/453762/ Maybe Dr. Freeman will explain this in plain English. The following user(s) said Thank You: pat1

Good News for Cirrhotic Patients 7 years 6 months ago #3179

DrJames
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It says get rid of Hep C using drugs and the chemical mediator LOXL2 that causes fibrosis also goes away.

Which explains why we see regression of fibrosis at VL=0 and SVR.

If you are F4 you will probably never regain F0 and SVR, but you may well be less F'd than currently so regression back to F3 or F2.

Improvements in fibroscan scores post cure are well documented

fixhepc.com/forum/experts-corner/106-liv...ear-in-12-weeks.html

This explains the underlying pathophysiology.

YMMV

The following user(s) said Thank You: klhilde, pat1, darbara

Good News for Cirrhotic Patients 7 years 6 months ago #3209

klhilde Topic Author Offline Elite Member Posts: 253 Karma: 6 Thank you received: 498	I'm guessing you mean "never regain F0 at SVR" "less F'd"