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TOPIC: Good News for Cirrhotic Patients

Good News for Cirrhotic Patients 5 years 11 months ago #3160

  • klhilde
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www.empr.com/aasld-2015/sofosbuvir-based...osis/article/453762/

Maybe Dr. Freeman will explain this in plain English.
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Good News for Cirrhotic Patients 5 years 11 months ago #3179

  • DrJames
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It says get rid of Hep C using drugs and the chemical mediator LOXL2 that causes fibrosis also goes away.

Which explains why we see regression of fibrosis at VL=0 and SVR.

If you are F4 you will probably never regain F0 and SVR, but you may well be less F'd than currently so regression back to F3 or F2.

Improvements in fibroscan scores post cure are well documented

fixhepc.com/forum/experts-corner/106-liv...ear-in-12-weeks.html

This explains the underlying pathophysiology.
YMMV
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Good News for Cirrhotic Patients 5 years 11 months ago #3209

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I'm guessing you mean "never regain F0 at SVR"

"less F'd" :lol:
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