Back in the day of IFN and Riba combo, if you were a geno 1 you were considered 'hard to treat'. If you were diagnosed a geno 2 or 3 you counted your blessings as you had a cure rate of 70 to 80% clearance rate. The poor old geno 1s were given at best a 50/50 chance of clearance and that we probably overblown data from the pharmas. With the new DAAs this thinking has changed and it is in fact geno 3 which can (if untreated) potentially cause the most damage. Check out the blog: Em
Geno 1b F2/3 snce early 80s. Treated in 2008_9 for 63 weeks on INF/Riba. Commence Sof/Dac on 6 October 2015 and completed 18 weeks of tx. UND at 4-6 weeks, UND at EOT, SVR 2, SVR 6 and SVR 12 on 6 May 2016.