Hi Rudy,
There are non-invasive, accurate tests that can accurately determine liver fibrosis levels. Get one and start treatment. My enzyme levels went from over 200 to 12 & 15 after a month on Harvoni.
Good luck,
Mike
My enzyme levels were like yours for many years and like mgalbrai’s dropped to the teens within weeks of starting treatment.
It is never to late to start treatment and put a halt to any damage the virus might be causing.
Good luck
S
Diagnosed: 2001 GT1a , HCV since mid-70's.
Biopsy 2010 F1
Fibroscan and Fibrosure 2018 F2
Treated in trial 2010 with Dac/Peg/ Riba and Relapsed.
Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac.
Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U)
VL start: 1.6mill.ALT 125 AST 88
Wk. 4 Det @LLOQ <15.
VL Wk.8 UND Alt &Ast 22
Wk. 12 UND
EOT:UND
The high AST/ALT are relatively meaningless and will get better with treatment.
Your low platelets and APRI do suggest you're probably F4 but here's the thing:
I've seen way worse
Treatment will arrest the progress of the disease and allow some recovery.
You are alive now so you have enough working liver to see you through.
We can't start treatment yesterday, so today is the best option.
Once you're cured the only long-term thing would be the occasional liver ultrasound to keep an eye on it for HCC (there is a 3% per annum risk in people with cirrhosis).
Hello Rudy, as Dr James said "Treatment will arrest the progress of the disease and allow some recovery". There is very strong evidence that the liver reverses much of the damage once the virus is eliminated, and many patients reported that their F4 level was reduced to F2 or F1 in the months following cure. So it's not too late.
If you start the process of obtaining meds today then you will be able to start treatment and see progress within weeks. My mental outlook completely changed once I had the meds. My anxiety and brain fog began to lift and things got exponentially better. Good luck. I will be looking forward to reading about your journey.
G4
F0-F1
diagnosed in 2006
Tx naive
Treatment started 8/12/16, Ledipasvir/ Sofosbuvir (Harvoni) supplied by Monkmed
8/1/16 ALT 36 AST 40
1/4/17 ALT 17 AST 21
7/13/17 ALT 17 AST 25
12/28/17 ALT 22 AST26
2/22/18 ALT 19 AST 25
7/10/18 ALT 26 AST 32
1/8/19 ALT 16 AST 28
7/2/19 ALT 16 AST 26
Hcv Rna, Quantitative Real Time Pcr <15 NOT DETECTED (IU/mL) NOT DETECTED
