Twinvir works well for types 1a, 1b, 2 and 4 ... not quite so good with type 3.
Twinvir is from Incepta from Bangladesh.
Incepta also has Hopetavir (sofosbuvir), and the new Virodacla (daclatisvir)
The sof/dac combo is better for type 3 and works very well across all genotypes.
Hi Nuribeslen - Twinvir is a new drug, there are quite a few patients sharing their treatment experiences on this forum now, although sometimes not in the same place so will involve some reading.
I believe the Redemption Trials have been set up for this reason and will provide more detailed answers hopefully.
I guess you can't get the results without waiting for patients to finish their treatments.
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
Twinvir works very well for the Genotypes mentioned above. There are many on other forums who have confirmed this.
Genotype 1 a & b
V/L 17 MILLION
Started Harvoni 11th Dec 2015 for 12 weeks
4 weeks VL UND
6 WEEKS ALT 32, AST 34
EOT 03/03 2016 ! UND
ALT 34, AST 26
04.04.2016 SVR 4
26.05.2016 SVR 12
16.08.2016 SVR 24