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psavic started TWINVIR treatment

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psavic started TWINVIR treatment 6 years 7 months ago #10649

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psavic wrote: PCR test results came back. I worked HCV RNA quantitative test 22 days of therapy, and writes only NEGATIVE :woohoo: .
I expected that says "<15 IU / ml" or "<15 IU / ml" or UNDETECTED but writes only NEGATIVE. .


Hi Psavic,
Only after 3 weeks! Well done !
For viral load NEGATIVE means UNDETECTABLE. :)
Happy for you, you won the battle.
Wish you all the best and only UND! :lol:
HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful :)
virus not detected 06.02.2016 & SVR24
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Last edit: by isaing4.

psavic started TWINVIR treatment 6 years 7 months ago #10672

Congrats Psavic! Wish you UND at 24 weeks SVR
Gt 1a, F0, VL 6.5 million, AST 59, ALT 62
Started Twinvir 1/15/16
6 wk. labs VL UND, AST 27, ALT 20
EOT labs VL UND, AST 23, ALT 19
SVR 16, VL UND, AST 28, ALT 17
SVR 24 , VL UND, 10/8/16
SVR 125, VL UND, 9/22/18
SVR 230, VL UND, 10/3/20
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psavic started TWINVIR treatment 6 years 7 months ago #10683

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Hi psavic,

Congratulations on you negative/undetected result! :woohoo:
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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psavic started TWINVIR treatment 6 years 7 months ago #10698

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explanation of the lab is recived:
"Hello, Mr. Savic, you don't have reason to worry about. When the result of the test is negative, it means that the quantity is 0. If the result was positive, then it would have contained quantity as well. Greetings!"
G1 F1 or F4 (I am not sure) 6. jan. 2014. -> Biopsy -> F1
24. dec. 2015 -> Fibroscan 16.3 kPa -> indicate chirosis
15. Jan. 2016 -> Fibroscan 10.2 kPa -> F3/F4
VL 30.000.000 - may 2015
VL 3.300.000 - dec 2015
Started TWINVIR treatment naive on January 13, 2016.
VL after 21 day UNDETECTED
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psavic started TWINVIR treatment 6 years 7 months ago #10762

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Congrats on reaching undetected Psavic!
3a F0 TX Naive
Started Tx 12/12/2015 Kingswood Sof/Dac

Pre Tx - ALT 71 AST 40 V/L 9 million
Day 11 - ALT 12 AST 15
4 week - LFTs normal - detected (same sample sent for v/l showed undetected) :/
6 week - UND
12 week EOT - UND
SVR4
SVR12
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psavic started TWINVIR treatment 6 years 7 months ago #10765

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Thank you all! I wish everyone a successful therapy :)
G1 F1 or F4 (I am not sure) 6. jan. 2014. -> Biopsy -> F1
24. dec. 2015 -> Fibroscan 16.3 kPa -> indicate chirosis
15. Jan. 2016 -> Fibroscan 10.2 kPa -> F3/F4
VL 30.000.000 - may 2015
VL 3.300.000 - dec 2015
Started TWINVIR treatment naive on January 13, 2016.
VL after 21 day UNDETECTED
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psavic started TWINVIR treatment 6 years 7 months ago #10872

Congratulations, psavic! That's great news! That's some massive VL you obliterated. Keep on blasting!

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psavic started TWINVIR treatment 6 years 7 months ago #10873

Right on!
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Genotype 3
VL 4,100,000
ALT 101 AST 71
Treatment Naive
Started Sof/Dac Jan 12, 2016
VL= <15 4 weeks in. AST/ALT normal.
VL=UNDETECTED 8 weeks in.
SVR4= Virus back. 3,300,000

Started generic Epclusa Sep. 23, 2017

4 weeks in <15 *Detected.
12 weeks in <15 *Not Detected.
16 weeks in <15 *Not Detected.
Finished 24 weeks treatment 3-17-18
SVR5 <15 Not Detected.
SVR 20 <15 Not Detected.
SVR 44 <15 Not Detected.

Thank you Jesus.
Thank you Dr. James

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psavic started TWINVIR treatment 6 years 7 months ago #10883

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That is great! Congrats! :+1:
GT2b diagnosed 10/2015
since: unknown
11/20/15 VL= 214,070
12/4/15 ALT=18 AST= 24
1/16/16 started sof/dac
2/13/16 @4wks VL=UND ALT=13 AST=22
3/12/16 @8wks VL=UND ALT=10 AST=18
4/9/16 EOT VL=UND ALT=11 AST=19
9/23/16 SVR24 ALT=11 AST=22

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psavic started TWINVIR treatment 6 years 7 months ago #11032

Great news and congrats.
Ashraful Islam
M.Pharm, MBA
Senior Group Manager
International Marketing
Incepta Pharmaceuticals Ltd.
Mobile: +8801713228112
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psavic started TWINVIR treatment 6 years 7 months ago #12065

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Day 49
I do not want to invoke the bad luck, but I feel a lot better these days, gone is the feeling of tension in the area of the liver. No side effects, it seems to disappear and afternoon fatigue.
I notice that when I wake up regularly 6 h, and went to take a piss, and then I can not sleep (regularly go to bed around 22 pm, so I can not say that I sleep a little) I do not know whether it has to do with therapy or with my 40 years. :)
G1 F1 or F4 (I am not sure) 6. jan. 2014. -> Biopsy -> F1
24. dec. 2015 -> Fibroscan 16.3 kPa -> indicate chirosis
15. Jan. 2016 -> Fibroscan 10.2 kPa -> F3/F4
VL 30.000.000 - may 2015
VL 3.300.000 - dec 2015
Started TWINVIR treatment naive on January 13, 2016.
VL after 21 day UNDETECTED

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Last edit: by psavic.

psavic started TWINVIR treatment 6 years 5 months ago #15227

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Day 107
I feel ok these days. No side effects.
Blood test, ALT, AST, GGT are OK. Less then 60 days to the end of tretmant... :cheer:
G1 F1 or F4 (I am not sure) 6. jan. 2014. -> Biopsy -> F1
24. dec. 2015 -> Fibroscan 16.3 kPa -> indicate chirosis
15. Jan. 2016 -> Fibroscan 10.2 kPa -> F3/F4
VL 30.000.000 - may 2015
VL 3.300.000 - dec 2015
Started TWINVIR treatment naive on January 13, 2016.
VL after 21 day UNDETECTED
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Last edit: by psavic.

psavic started TWINVIR treatment 6 years 5 months ago #15228

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Good to hear your Tx is going well, psavic. :cheer:
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:

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psavic started TWINVIR treatment 6 years 5 months ago #15231

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psavic
keep going, keep going
all will be well
good to hear from you #flower
gt 1a VL 6m
F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015
sof/dac 10 December for 12 weeks
pre tx alt 85 ast 51
4 wk alt 34 ast 31 UND <35
8 wk alt 29 ast 32 UND <15
12wk alt 25 ast 25 EOT 3.3.16
SVR24 UND KPa5.3 F0 in normal range
I am well
.forever grateful to fixhepc

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psavic started TWINVIR treatment 6 years 5 months ago #15292

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Thanks for updating us and good luck for the last leg of tx
Looking forward to your EOT
sending hugs from Ariel
#flower
Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18

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