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TOPIC: Twinvir versus Lesovir-c

Twinvir versus Lesovir-c 6 years 7 months ago #1004

  • Enkel
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Hi All,

Anyone any information about these two generic harvoni: Twinvir versus Lesovir-c

Which is better and tested?

I appreciate any info?
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
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Twinvir versus Lesovir-c 6 years 7 months ago #1017

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I am guessing they are equally good

The chinese are going to use beximco meds soon

bbs.kangantu.com/forum.php?mod=viewthrea...d=122&extra=page%3D1
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Twinvir versus Lesovir-c 6 years 7 months ago #1018

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THANK YOU

I have a friend of a friend in Banglandeshi. And I dont know if 12 bottles of Lesovir that is 12 week are big for customs. They have a hudge packing.
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
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Twinvir versus Lesovir-c 6 years 7 months ago #1019

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If u managed to buy, let us know

Hope your mother in law get well soon
Let us know her lab results
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Twinvir versus Lesovir-c 6 years 7 months ago #1020

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I am another guy, i need it for myself. I am F1 and I wonder why I have ALT fluctuating from 40-80(relatively low) while i have a viral load 5 million. Where this hudge viral load replicates? Maybe in my nervous system as i suffer anxiety, depresion. That why I want to treat.

Thanks
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
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Twinvir versus Lesovir-c 6 years 7 months ago #1021

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We have tested Twinvir. Happy to test Lesovir-c if anyone wants to send me a tablet.

Anyway go here: fixhepc.com/blog/item/16-testing-provisions-patient-safety.html and search the NMI Certificates for Twinvir.

Here's one doc: fixhepc.com/images/coa/NMI-NATA-Sofosbuvir-Certification.pdf

And it says:

The 1H NMR matches that for a sample of sofosbuvir extracted from tablets
of Twinvir™, and the spectrum reported in J. Med. Chem., 2010, 53, 7202-
7218.
YMMV
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Twinvir versus Lesovir-c 6 years 7 months ago #1022

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Hi Doctor,

In a few words, the twinvir is good quality?

Lesovir uses solid solid dispersion for the component ledispavir.
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
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Twinvir versus Lesovir-c 6 years 7 months ago #1023

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and the Ledipasvir used, is this tested? Thanks
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
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Twinvir versus Lesovir-c 6 years 7 months ago #1024

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Hi Doctor,

Where to send the tablet Lesovir-C? What address?
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured
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Twinvir versus Lesovir-c 6 years 7 months ago #1025

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My bad
I think I have brain fog
I mistook u for the guy whose mother (or mother in law) need the meds
Sorry.....
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Twinvir versus Lesovir-c 6 years 7 months ago #1026

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what about the amount of ledipasvir in a tablet of Twinvir ?
it is the right amount ?
thank you
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Twinvir versus Lesovir-c 6 years 7 months ago #1028

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You could send it to:

Dr Greg Tarrant
Senior Synthesis Chemist, Chemical Reference Materials
Ph: +61 2 9449 0180 | Fax: +61 2 9449 0292
This email address is being protected from spambots. You need JavaScript enabled to view it.
National Measurement Institute
105 Delhi Rd, North Ryde, NSW 2113, Australia

Normally it would be:

Dr Stephen Davies
Team Leader, Chemical Reference Materials
Ph: +61 2 9449 0183 | Fax: +61 2 9449 0292
This email address is being protected from spambots. You need JavaScript enabled to view it.
National Measurement Institute
105 Delhi Rd, North Ryde, NSW 2113, Australia

But he is away for 3 weeks.

The National Measurement Institute did our testing.
YMMV
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Twinvir versus Lesovir-c 6 years 7 months ago #1029

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Yes, that is on the blog fixhepc.com/blog/item/16-testing-provisions-patient-safety.html too:

fixhepc.com/images/coa/NMI-NATA-Ledipasvir-Certification.pdf

The 1H NMR matches that for a sample of ledipasvir extracted from tablets of Twinvir™.
YMMV
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Twinvir versus Lesovir-c 6 years 7 months ago #1043

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Dear Enkel,
Twinvir. has small package. Each box contain six tablet, thus you need only 14 box. You can tell your friend to contact with me. I can help him this.
Phone: +8801730352074.
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Twinvir versus Lesovir-c 6 years 7 months ago #1098

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i dont know where i read that someone send Lesovir-c for testing
an update on this will be helpful ,it is arrived ?, tested ?....
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