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OTC antihistamines for the rash prone 6 years 11 months ago #1581

  • dointime
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Hi all,

I got a bad rash the last 2 times I did tx. Nothing was much good once it developed, I just suffered through it. On a scale of 1 - 10 where 10 is admittance to A&E I'd say I was sometimes a 9. As I will again be taking ribavirin, I am thinking about taking OTC antihistamines regularly as a preventative, paying attention to which ones make you drowsy and which don't.

So my questions are - is this a good idea?
I can't find any drug interactions with sof, dac or led that contraindicate these meds, so is it safe?

Meds in question are these, all anti-allergy category:

Cetirizine hydrochloride 10mg, one-a-day, non-drowsy
Loratadine 10mg, one-a-day, non-drowsy
Chlorphenamine maleate 4mg, one tab every 4-6 hours, can make drowsy
Acruvastine
Diphenhydramine (Benadryl)

There are several more but that will do for now. Are there any of these preferred for rashes, either before or during a rash?

Thanks
dointime

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OTC antihistamines for the rash prone 6 years 11 months ago #1584

This article discusses "Drug Eruption Medications" which along with "Fixed Drug Eruption" is secret doctor code for a rash caused by drugs:

emedicine.medscape.com/article/1049474-medication

A Google for the search term "Fixed drug eruption treatment" should turn up many more articles.
YMMV
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OTC antihistamines for the rash prone 6 years 11 months ago #1621

  • emilio
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Hi DT

I'm taking similar for my hayfever/seasonal stuff here. I put cetereizine through the interactions tool and it came up orange and it went further to say that this particular antihistimine shares enzymes with the daclatasvir??? Probably nothing that would impact and there is no research, so I've decided to steer clear and opted for laratadine which is green lighted. It's a shame because friends swear by the ceterezine. Em
Geno 1b F2/3 snce early 80s. Treated in 2008_9 for 63 weeks on INF/Riba. Commence Sof/Dac on 6 October 2015 and completed 18 weeks of tx. UND at 4-6 weeks, UND at EOT, SVR 2, SVR 6 and SVR 12 on 6 May 2016.
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