TOPIC:

Sof/Dac 84 or 90 Dosage? 6 years 10 months ago #2358

Joan
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Hello
I received my meds yesterday. I bottle Sofosburvir I bottle of Daclastavir. However, there were 84 capsules in each bottle.
I was expecting 90 capsules'. On the prescription my Dr. wrote 90 caps and same on the order form.

I'm just wondering if 84 is the correct dosage or do I need 90 for the whole course?
Thanks

GT2B Diagnosed 1989
Started Tx 6.Nov.2015
F3 Fibroscan 17: April.2015
Alt PreTx: 186 Ast PreTx: 157 VL PreTx: 733,000 27.10.2015
Alt Week 4: 14 Ast Week 4: 28 VL Week 4: UND 7.12.2015

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Sof/Dac 84 or 90 Dosage? 6 years 10 months ago #2361

Paul-Jarman-facebook Offline Moderator The gypsy woman told my mother Before I was born Posts: 383 Thank you received: 659	84 is 12 weeks which is whats recomended Joan Two time relapser. SVR 4 achieved 12/16 at last SVR 12 achieved 22/02/2017 The Bastard has been defeated GT 3 - about 28 yrs with HCV
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Sof/Dac 84 or 90 Dosage? 6 years 10 months ago #2364

Joan Topic Author Offline Senior Member Posts: 71 Thank you received: 95	Thanks Paul thats great to hear. I'm glad I've clarified it. GT2B Diagnosed 1989 Started Tx 6.Nov.2015 F3 Fibroscan 17: April.2015 Alt PreTx: 186 Ast PreTx: 157 VL PreTx: 733,000 27.10.2015 Alt Week 4: 14 Ast Week 4: 28 VL Week 4: UND 7.12.2015
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Sof/Dac 84 or 90 Dosage? 6 years 10 months ago #2370

Joy
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90 is written on both my bottles but I didn't count until today (day 25) and 90 it was.

I was planning to stop at day 84 anyway (if I'm clear) and then ... give the rest away?

NSW Australia. Genotype 1b 30+ years, F0-F1, VL 91,000 Feb 2015 (740,000 in 2010), Tx naive.
Ordered Sof/Dac from Buyers Club 21 Sept, received 14 Oct.
Virus UNDETECTED at 3 weeks AND 12 weeks (EOT) AND SVR4 AND SVR12 AND SVR24. :-)

A thousand thankyous to Dr James and the amazing FixHepC team.

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Sof/Dac 84 or 90 Dosage? 6 years 10 months ago #2386

DrJames
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Hello Joy,

This was my error. Before I knew more I knew less. Mesochem supplied in a standard quantity of 36 g (90 x 400 mg) so I made the incorrect assumption that it was 90 days treatment, rather than 84. To be totally compliant with the guidelines we now use 84 days.

If it was me I would reserve the extra 6 to resume treatment in the (unlikely) event of recurrence. That will minimise any delay while further medication is shipped to you.

Over treating for 6 days should not cause any harm, but given the recent Gecko data the 8 weeks works well for most people we are probably overtreating by quite a bit with the 84 day course.

The trouble is we can only ever know we under treated....

YMMV

The following user(s) said Thank You: tweakmax, Joy, mgalbrai, Joan

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Last edit: by DrJames.