Hello doctor J. Freeman , I'm from the distant Tajikistan wanted to ask about my analysis, can you comment on and prescribe me drugs that inhibit the hepatitis C virus , I was just confused in their analyses and recommendations of our doctors . Here are my tests using IgG+ , IgM+, Core+, Ns3+, Ns4+ Ns5 - Ns5 which means - and I was first offered a course of treatment with Daclatasvir and Sofosbuvir however, after these analyses and Asunaprevirum assigned Sofosbuvir and peg-intron + Sofosbuvir+ Ribavirin I hope only for your answer I do not know what to do I already bought medicines of Daclatasvir and sofosbuvir . Advance very grateful , although I'm from far away but thankful to your forum . and separately you Doctor.
Sofosbuvir/Daclatisvir combo is working well across all genotypes, but depending on the condition of your liver you may either need to extend treatment from 12 weeks to 24 weeks and/or add ribavirin to the mix.
If you already have the Sof and Dac you're almost there!
Thank you very much Klhilde and Doc Freeman yeah sorry I wrote You the complete picture of my illness, I have Genotype 1b In naïve, never treated me according to the analysis of no in Tajikistan fibrosis fibroscan or biopsy and tests the doctor is not appointed , the clinical analysis of blood hemoglobin to -126.6, 258,6- platelets leukocytes- 6,2 GGT- in 11.05, 11- AST , ALT-33,1 Total bilirubin 10,2 just a little albumin-31,6,creatinine-76,6, alkaline phosphatase - 171,4 coagulation normal . I am 30 years old and a huge thank you for the information and I showed a recommendation for the treatment of hepatitis to the doctor and he supported you and offered to start treatment.
Amed, could I please offer my thought on testing/geno type etc. I am not a doctor but believe I'm 'well' read enough to provide some input.
Your genotype 1b will do really good on sofosbuvir and daclatasvir, for either 12 or 24 weeks. Please don't consider IFN/Riba in combo. The Direct Acting Anti-Virals is what you need. Now I said 12 or 24 weeks and this will depend on your fibrosis score. If it happens to be F0-F2, 12 weeks will be sufficient, however if 3-4 cirrhosis you will need 24 weeks? If you have access and capacity to purchase 24 weeks commence asap. If you have 12 weeks now and the opportunity to purchase another 12 weeks, the same thing. If the test for fibrosis is F3-4 you can order the additional 12 weeks later, once you commence. I'm thinking you have 12 weeks of sofosbuvir and daclatasvir and also your Doctor is wanting you to go with IFN/Riba with sofosbruvir. . DAAs is the way to go mate. Em
Geno 1b F2/3 snce early 80s. Treated in 2008_9 for 63 weeks on INF/Riba. Commence Sof/Dac on 6 October 2015 and completed 18 weeks of tx. UND at 4-6 weeks, UND at EOT, SVR 2, SVR 6 and SVR 12 on 6 May 2016.
Sure I'll tell what is my treatment with Daclatasvir production of Bangladesh Julphar Bangladesh Ltd Daclacee and Sofosbuvir from India company Natco. Thanks you all for your support and help. With respect Dilrabo from Tajikistan .Everyone is waiting for my results with the drugs from Bangladesh
dear Doc I would like to know the results , although I started taking Duck Bangladeshi today , but I really want to know the answer to your testing, I hope not mistaken with the order of daclatasvir(Daclasee) , and if possible to find out the date the answers to the test.
Hello here is my analysis for December 10, 2015 and cheers Bangladeshi Daclacee works I have not found the virus sensitivity was 50 copies per ml , why is the platelet count increased to 402 our lab norm from 180 to 400 -10^9/l . I do not know because of what so increased advise what I should do . Thank you sincerely Dilrabo
While it would be nice to see a quantitative test with lower detection levels (generally 15 copies/mL, one I've read is 5 copies/mL) since you are only 3 weeks into treatment, even using a test with a 50 copies/mL threshold is a great result.