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TOPIC: Managing Patients After DAA Treatment Failure
Managing Patients After DAA Treatment Failure 6 years 2 months ago #12071
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YMMV |
Managing Patients After DAA Treatment Failure 5 years 11 months ago #16911
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Managing Patients After DAA Treatment Failure 5 years 11 months ago #16934
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Managing Patients After DAA Treatment Failure 5 years 11 months ago #16935
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Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog. Started Sof+Dac from fixHepC 10-Nov-2015. NO sides. Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000. Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3). |
Managing Patients After DAA Treatment Failure 5 years 11 months ago #16936
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Managing Patients After DAA Treatment Failure 5 years 11 months ago #16937
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GT 1a (~1968) Diagnosed Non A/B ’85 – HCV ‘89 Rebetron INF/RBV 17 months 2000 – Failure Infergen INF/RBV 11 months 2002 – Failure Viekira Pak + RBV 12 weeks 2015 – Failure VL Und at +3 weeks > EOT – EOT+12 weeks 2,240k Resistance Tests – NS5a Q30R SMV/DCV/SOF + RBV 24 weeks 2016 VL Det <15 +2 and +4 weeks – Und +8 weeks > EOT SVR4, SVR12 and SVR24 Undetected |
Managing Patients After DAA Treatment Failure 5 years 11 months ago #16938
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Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog. Started Sof+Dac from fixHepC 10-Nov-2015. NO sides. Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000. Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3). |
Managing Patients After DAA Treatment Failure 5 years 11 months ago #16940
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Managing Patients After DAA Treatment Failure 5 years 11 months ago #17026
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Managing Patients After DAA Treatment Failure 5 years 10 months ago #19605
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GT3a 1990 Failed Inter 1998, comb in 2000. HCC 2012 Started 24/52 Sof/Dac 27th October 2015. 1. Bloods 2 October 2015: AST - 165 (20-40), ALT - 265 (5-40), GGT 189 (5-50) 2, Bloods 20 November 2015: ALT etc normal; VL 19 3. Bloods 8 January 2016: AST - 40, ALT - 59, GGT 48 VL RNA UND 4. EOT 12 April 2016 - blood tests: all is well, CT scan: okay 5. AFP 11 June 2016: 4 ref< 11 6. VL July 2016: DET 7. Oct16 start treat - June17 UND 8. Jun 18, lfts okay, platelets a bit low. |
Managing Patients After DAA Treatment Failure 5 years 10 months ago #19609
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YMMV |
Managing Patients After DAA Treatment Failure 5 years 10 months ago #19611
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Managing Patients After DAA Treatment Failure 5 years 10 months ago #19613
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Failed Interferon 96', G1a, VL = 9 - 5.5 Million, F3/A3, AST 111, ALT 190, Generic DAA treatment Sof/Led (Mylan - India MYHEP LVIR) - 8 June, 2016 2 Week Results 20 June, 2016 AST 19, ALT 32 4 Week Results 06 July, 2016 AST 22, ALT 30, VL = 35 6 Week Results 20, July 2016 VL only = HCV RNA Detected, Non-Quantifiable <15 8 Week Results 04 August 2016, Labs, LFTs Normal, VL = UND 12 Week Results 31 August, 2016 LFTs Normal, VL = UND EOT + 4 Weeks, LFTs Normal, VL = UND, "SVR4" SVR12, 21 Nov 2016. CURED!!! |
Managing Patients After DAA Treatment Failure 5 years 10 months ago #19625
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Contracted HCV 1980's Geno Type 1a F3 ( doc says once treated I'll be F2 maybe F1) Meds shipped 6/17/2016 arrived early 7/2016 Viral count - 3,471,080 4 week quantitative bloods: August 17, 2016. I have been diagnosed as <15 (told undetected) 8 week quantitative bloods: September 14th. I have been diagnosed as <15 (told undetected) 11 week PCR RNA Qualitative bloods: September 26th 2016 - Undetected December 19th 2016: Cured! Viral count: zero!!! 2018 viral count: still zero! Cured! |
Managing Patients After DAA Treatment Failure 5 years 10 months ago #19629
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G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND ![]() ![]() ![]() |
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