B12 supplements may improve SVR

This topic has 25 replies, 14 voices, and was last updated 8 years, 2 months ago by fretboard.

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2 January 2016 at 2:19 pm #7818
Dr James
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- Guardian Angel
@fixhepc
Here is the full article http://onlinelibrary.wiley.com/doi/10.1002/hep.21116/full

YMMV
2 January 2016 at 4:33 pm #7829
LondonGirl
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@londongirl
Phew – Short version easier for me !
Will just take your advise Dr F

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
4 January 2016 at 3:31 am #7915
Ariel
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@ariel
Thanks for all this good information. I just called my GP and in July my ferratin was at 80 which is low end normal I think. I pick up a path request tomorrow morning for a B12 and LFT request as my meds are on the way. Keep the good oil coming and thanks again for the links James and the conversation everyone. I did a bit of a pantry makeover and have added almonds hazelnuts dried apricots oat bran and more yummies that are B12 rich
4 January 2016 at 3:49 am #7918
zhuk
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@zhuk
Good to hear you’re gearing up for treatment now Ariel. Reading your ferritin score, I checked out a blood test I had done by my GP in Nov (my liver clinic don’t usually bother to check iron/B12 etc) and my level is 66 – right, confused now as no doc has mentioned it before. Weirdly my B12 is over the maximum stated range (765) which doesn’t seem to make a whole lot of sense.

One thing I’ve learned about the past year spent in and out of public hospitals/waiting rooms is that you can get some very contradictory opinions from the medical profession on the same subject lol

GT1a since 1988, diagnosed 1990
F0, tx naive
VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
Started Mesochem sof/dac 12 weeks 01/01/2016
11/02/2016 – 6 weeks UNDETECTED
AST 26
ALT 26
9 July 2016 at 10:29 am #20736
LondonGirl
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@londongirl
Back to the B12 subject, I stopped taking Vit B12 when I started the 3rd med for the last 4 weeks.
This was because I have to take Asunprevir twice a day.
Last bloods 2 weeks ago showed Neuts were low (not very, but slightly and flagged).
Looked it up and it said this can be due to VitB12 being low, which I had suspected before and why I decided to take extra.

There were some suspicions I had mal/low absorption, so even though I only have a few days left on the meds, I’d like to know if I can take it for my last few days.

There is very little advise re Asunprevir, so if anyone knows or can find the answer, it would be great to get the advise for my last few days on the meds, to try and make sure I’m absorbing meds as well as I can, albeit nearing EOT.

Thanks in advance
LG

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
11 July 2016 at 9:31 pm #20833
Dr James
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@fixhepc
Yes you can take B12

YMMV
12 July 2016 at 11:59 am #20855
LondonGirl
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- Guardian Angel
@londongirl
I made the right decision

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
25 August 2016 at 4:55 am #22502
sb409us
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- Novice
@sb409us
Regarding the high serum levels of B12. I just recently read that because B12 is stored in the liver, if the liver is not healthy, more B12 might be circulating in the blood since the liver cannot effectively store it.

GT 1a
Fibrosis 2
Age 55
Started Harvoni tx 6/21/2016
4 week labs Undetected
EOT 8/15/2016 Undetected
26 August 2016 at 8:36 am #22553
fretboard
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@fretboard
”James-Freeman-facebook” wrote:

Note: While an injection of B12 is the fastest way to get your levels up it can be taken as tablets.

Personally I prefer the shots, I get one at least quarterly. They make me feel better, especially during tx. Not that I felt bad but they seemed to give me a little charge. Maybe like a double shot Starbucks but better. They don’t get me wired, they just make me feel better for the first few minutes. I just snatched the blurb below from the clinic I go to. You could probably get one from your MD but mine never would give it up, unless I took a blood test and that dog don’t hunt! I get the $15 one.

Vitamin B12 Shot $10 Regular 500 mcg shot $10, 1,000 mcg shot $15

G1a dx’d in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn’t last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND
30 August 2016 at 3:10 am #22635
Greedfighter
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@greedfighter
I take a B-100 everyday, has 100 mcg. of B-12. B-Complex is a good vitamin to take, as well as C and D.
1 September 2016 at 11:10 am #22714
fretboard
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@fretboard
Greedfighter wrote:

I take a B-100 everyday, has 100 mcg. of B-12. B-Complex is a good vitamin to take, as well as C and D.

Yep, tablets, sublingual or whatever especially on tx but even afterwards. I actually take only B12 shot and D3 gelcap, I also take amino acids but I ran out. Gotta get more, cause they make me feel better. And who wouldn’t want to feel better. Below is a link on B12 deficiency.

https://labtestsonline.org/understanding/conditions/vitaminb12/

G1a dx’d in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn’t last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND
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