Extending TX +4 or 6 weeks

This topic has 5 replies, 4 voices, and was last updated 8 years, 7 months ago by MtGoat.

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13 April 2016 at 8:13 am #15383
MtGoat
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- Recovery Champion
@mtgoat
Yesterday I read a post about 3a relapses, saw Dr James’ response & saw on some related posts that a few extra weeks would be a good idea. Just as I was on a five day count down to EOT (12 weeks). Anyway, after losing sleep last night, I went ahead and ordered a 6 week supply. The thing is, I’ll run out of what I have. There will be about a 4 day lapse of TX. Does that seem terrible to anyone? Has anyone else missed a few days during TX?
Thanks for any feedback.

Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed
13 April 2016 at 8:33 am #15384
Gaj
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- Guardian Angel
@gaj
Hi MtGoat,

How are you shipping? Would FedEx door to door help shorten timing? I can usually get US to Aust in about 5-6 days including w/ends.

G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
13 April 2016 at 8:42 am #15385
MtGoat
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- Recovery Champion
@mtgoat
Hey Gaj, I think it’ll only take 5 or 6 days, but I won’t be returning from a trip for a couple days after that. I’ve already laid money down for the trip & leaving in 3 days. I could take what I have left every other day. But, just hard to know what’d be best.

Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed
13 April 2016 at 9:52 am #15387
Paul-Jarman-facebook
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- Guardian Angel
@paul-jarman-facebook
Why not spread your remaining doses out and take them every 48 hrs. The meds have a 1/2 life of 27 hrs which means they stay in our system for many weeks at a reduced dosage.

Or split them and take 1/2 per day.

cheers

Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated

GT 3 – about 28 yrs with HCV
13 April 2016 at 3:18 pm #15411
Dr James
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@fixhepc
Why not spread your remaining doses out and take them every 48 hrs. The meds have a 1/2 life of 27 hrs which means they stay in our system for many weeks at a reduced dosage.

Rationing is definitely the way to go, but rather than every other day (and provided you’re up for it) if you have a shortfall the best way would be to open the capsules/split the tablets in 1/2 and take 1/2 a dose each day. Not as good as a full dose every day, but much better than a complete break. Failing that every 48 hours is a good option.

YMMV
13 April 2016 at 5:22 pm #15414
MtGoat
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- Recovery Champion
@mtgoat
Dr. James,
Thank you very much. I was hoping you,d advise. Much appreciated!
And thanks to you too Paul.

Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed
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