Hi Chris, welcome.
Hmmm that is tough, I would say it sounds like actual flu or chest infection or whatever, not the treatment because what they mean by flu-like symptoms is temperature changes, aching bones, shivers, maybe headaches- but not the chest or much runny nose like actual infection or bug brings.
I’m not a doctor, can’t answer if it matters on treatment but lots of people have all sorts of stuff happen in the weeks on DAA’s, never heard of there being any connection with flu and not getting cured.
I’d say the usual advice, keep up fluids, watch your temperature, take paracetamol. Hope you feel better asap.

Hello Chris, and welcome to the forum. Like Hazel said, I’ve never heard that getting the actual flu during DAAs treatment can affect your cure chances, but I’m not a doctor as well, so hopefully you will get confirmation from Dr James here soon. If it turns out to be actual flu and not ‘flu like” sumptoms (which are very common with DAAs treatment), please make sure not to take any medication that may interact with Epclusa. Here is an excellent page where you can easily check any such interaction https://www.hep-druginteractions.org/checker Hang in there, it will all be so worth it soon

Hi Chris,

Welcome to the forum. Normal doses of paracetamol or ibuprofen are both fine on DAA treatment.

There is both a flu-like illness (but without the cough and mucus) and a runny nose/sore throat type thing that can happen with DAA treatment.

From what you describe I’d be agreeing with you that you do have something more than just side effects.

What colour is the mucus you’re coughing up?
Do you take any other medications?
Any other medical problems besides the Hep C?

Hi Chris,

No this won’t affect your treatment success rate.

In smokers who start coughing up stuff with colour I have a reasonably low threshold for prescribing antibiotics.

Normal smokers cough sputum is white. Viral sputum tends to be yellow and bacterial infection (that will respond to antibiotics) tends to be green(er) but there’s not a lot of visible difference.

The trend is an important thing. You start off well and go downhill. If you keep getting worse that’s a worry, if you stop getting worse and just settle into miserable that’s more ammenable to wait and see.

What country are you in?

Hi Chris,

Let’s see how you are tomorrow. If you’re worse some antibiotics would be a reasonable idea.

We can sort that out easily enough.