HCV New Drugs Blogspot

This topic has 175 replies, 27 voices, and was last updated 7 years, 11 months ago by mgalbrai.

Viewing 15 posts - 151 through 165 (of 176 total)

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11 June 2016 at 7:48 pm #18919
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
This is hell on a phone…

Drug Rationing Plays Russian Roulette With Patients’ Lives
http://hepatitiscnewdrugs.blogspot.com/2016/06/drug-rationing-plays-russian-roulette.html?m=1

2,436 patients with hepatitis C in one Alabama ER since implementing widespread testing in 2013
http://hepatitiscnewdrugs.blogspot.com/2016/06/2436-patients-with-hepatitis-c-in-one.html?m=1

Survival rates rise with new hepatitis C treatments
http://hepatitiscnewdrugs.blogspot.com/2016/06/survival-rates-rise-with-new-hepatitis.html?m=1

****4 Week Tx*****
Regulus Reports Positive Data/Phase II studies of RG-101 for the treatment of Hepatitis C
http://hepatitiscnewdrugs.blogspot.com/2016/06/regulus-reports-positive-dataphase-ii.html?m=1

Foretelling toxicity: FDA researchers work to predict risk of liver injury from drugs
http://hepatitiscnewdrugs.blogspot.com/2016/05/foretelling-toxicity-fda-researchers.html?m=1

FDA warns against fake Hepatitis C medicines
http://hepatitiscnewdrugs.blogspot.com/2016/05/fda-warns-against-fake-hepatitis-c.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
15 June 2016 at 8:58 am #19090
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Outcomes in patients with chronic Hep C treated with different anti-viral regimens

http://hepatitiscnewdrugs.blogspot.com/2016/06/outcomes-in-patients-with-chronic-hep-c.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
16 June 2016 at 10:26 pm #19244
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Making Hepatitis C A Rare Disease In The United States

http://hepatitiscnewdrugs.blogspot.ro/2016/06/making-hepatitis-c-rare-disease-in.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
23 June 2016 at 3:12 am #19790
Gaj
- Topics: 29
- Replies: 1,402
- Total: 1,431
- Guardian Angel
@gaj
A new non-DAA about to commence Phase 1 trials. Looks like it may have potential for ‘difficult to treat’ cases if proven.

http://hepatitiscnewdrugs.blogspot.com.au/2016/06/enanta-initiates-proof-of-concept-study.html

G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
23 June 2016 at 3:37 am #19792
Ariel
- Topics: 3
- Replies: 1,060
- Total: 1,063
- Guardian Angel
@ariel
mgalbrai wrote:

Outcomes in patients with chronic Hep C treated with different anti-viral regimens

http://hepatitiscnewdrugs.blogspot.com/2016/06/outcomes-in-patients-with-chronic-hep-c.html?m=1

“Interferon- and ribavirin-containing regimens negatively impact patients’ experience. ”
They can pop that in BOLD!
25 June 2016 at 11:59 pm #19946
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Now that we have the hepatitis C virus on the run, can a universal cure be attained?

http://hepatitiscnewdrugs.blogspot.com/2016/06/now-that-we-have-hepatitis-c-virus-on.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
26 June 2016 at 3:22 am #19947
Hazel
- Topics: 45
- Replies: 369
- Total: 414
- Guardian Angel
@hazel
Thanks Mike. they had a good list of references, but were missing an important one. I added a highlight from latest Liver International journal.

Genotype 3 30 years, 2x treatment interferon/ribavirin non responder. Cirrhosis 17 years. Fibroscan, decompensating, 40 down to 22 by 29/3/16- now down to 6.5, normal, no cirrhosis. Started Buyers Club Sof/Dac 14 Nov 15. SVR 12 29/0716
26 June 2016 at 3:42 am #19948
pat1
- Topics: 5
- Replies: 334
- Total: 339
- Guardian Angel
@pat1
mgalbrai wrote:

http://hepatitiscnewdrugs.blogspot.com/2016/06/now-that-we-have-hepatitis-c-virus-on.html?m=1

Ty Mike, many interesting studies to read plus
some good coffee news p5

Setiawan and colleagues[16] evaluated the protective effect of coffee drinking in black, Native Hawaiian, Japanese American, Latino, and white patients with chronic liver diseases. Regular coffee intake was associated with reduced risks for NAFLD-related progression in a dose-dependent manner. For example, compared with non–coffee drinkers, those who reported drinking two to three cups and four or more cups of coffee per day had a 14% and a 34% reduction, respectively, in the risk for NAFLD-related disease. High consumption (four or more cups per day of regular coffee) was associated with a reduced risk for HCV-related chronic liver disease.[/I]

gt 1a VL 6m
F2/3 FibroScan – 9KPa in 2011 and 7KPa in 2015
sof/dac 10 December for 12 weeks
pre tx alt 85 ast 51
4 wk alt 34 ast 31 UND <35
8 wk alt 29 ast 32 UND <15
12wk alt 25 ast 25 EOT 3.3.16
SVR24 UND KPa5.3 F0 in normal range
I am well
.forever grateful to fixhepc
8 July 2016 at 1:46 am #20677
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
HCV Guidelines Update: Reflect Recent Approval of Epclusa (Sofosbuvir/Velpatasvir)

http://hepatitiscnewdrugs.blogspot.com/2016/07/hcv-guidelines-update-reflect-recent.html?m=1

Velpatasvir/Sofosbuvir Makes HCV Treatment Simpler, Especially For Genotypes 2 and 3

http://hepatitiscnewdrugs.blogspot.com/2016/07/velpatasvirsofosbuvir-makes-hcv.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
8 July 2016 at 10:07 pm #20724
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Gilead’s Epclusa® – European Commission Grants Marketing Authorization

http://hepatitiscnewdrugs.blogspot.com/2016/07/gileads-epclusa-european-commission.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
11 July 2016 at 7:59 pm #20823
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Epclusa among hepatitis drugs that are medical miracles of the 21st century

http://hepatitiscnewdrugs.blogspot.com/2016/07/epclusa-among-hepatitis-drugs-that-are.html?m=1

Hazel Heal!!!

http://hepatitiscnewdrugs.blogspot.com/2016/07/listen-hep-c-buyers-club_11.html?m=1

Watch – New Opportunities and Challenges in Hepatitis C

http://hepatitiscnewdrugs.blogspot.com/2016/07/watch-new-opportunities-and-challenges.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
12 July 2016 at 7:07 pm #20871
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Generic Medications for Hepatitis C

http://hepatitiscnewdrugs.blogspot.com/2016/07/generic-medications-for-hepatitis-c.html?m=1

Hmmmmm…

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
17 July 2016 at 8:39 pm #21010
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Treatment of Chronic Hepatitis C in the Aged – Does It Impact Life Expectancy? A Decision Analysis

http://hepatitiscnewdrugs.blogspot.com/2016/07/treatment-of-chronic-hepatitis-c-in.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
29 July 2016 at 2:26 am #21564
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
David Bernstein: Managing Risk Factors in Hepatitis C

http://hepatitiscnewdrugs.blogspot.com/2016/07/treating-liver-disease-beyond-hepatitis.html?m=1

UK health service under fire over access to hepatitis C drugs

http://hepatitiscnewdrugs.blogspot.com/2016/07/uk-health-service-under-fire-over.html?m=1

New medication shows promise against liver fibrosis in animal studies

http://hepatitiscnewdrugs.blogspot.com/2016/07/new-medication-shows-promise-against.html?m=1

http://hepatitiscnewdrugs.blogspot.com/2016/07/adding-ribavirin-to-newer-daa-regimens.html?m=1

Discovery of new Hepatitis C Virus mechanism

http://hepatitiscnewdrugs.blogspot.com/2016/07/discovery-of-new-hepatitis-c-virus.html?m=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
9 August 2016 at 11:10 pm #22025
mgalbrai
- Topics: 28
- Replies: 1,298
- Total: 1,326
- Guardian Angel
@mgalbrai
Elbasvir-grazoprevir works effectively against HCV despite current drug use
https://hepatitiscnewdrugs.blogspot.com/2016/08/elbasvir-grazoprevir-works-effectively.html

‘Tax haven’ Ireland accused of helping US firm treble untaxed profits
https://hepatitiscnewdrugs.blogspot.com/2016/08/tax-haven-ireland-accused-of-helping-us.html

Why are hepatitis C patients treated differently by NHS England?
https://hepatitiscnewdrugs.blogspot.com/2016/08/why-are-hepatitis-c-patients-treated.html

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
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