A quick question on Molnupiravir. Dr. James, you mentioned in another thread that Molnupiravir is mutagenic.

Wouldn’t dispensing a mutagenic to individuals infected with a pathogen potentially cause mutations within the pathogen itself, leading to a host of mutated and potentially dangerous variants?

If so, were one to multiply this effect by a vast number of individuals receiving the mutagenic, couldn’t this lead to potentially hundreds of thousands, or even millions of variants within a relatively short timespan?

Also, if this were the case, and an endless variety of variants were suddenly circulating, it stands to reason that the mutated variants will inevitably be passed along, infecting and re-infecting individuals being treated with the Monulpiravir mutagenic. This in turn would most likely lead to a further exponential propagation of double, triple, quadruple, etc. mutated variants.

It simply seems to me that attempting to treat a potentially deadly virus with a known mutagen is a very, very, bad idea indeed.

I hope so too, Doc. I think of my friends in Australia often, and keep you in my prayers.

BTW I was hospitalized last summer with a nasty fast onset Pneumonia that had me coughing up blood, and presenting at the ER with an O2 level of 78%. Every shallow breath was painful.

Tested negative for Covid twice. Although I was put on IV antibiotics for suspected bacterial pneumonia, CT Scans revealed ground glass opacities in my lungs indicative of atypical viral pneumonia. I was on 6 liters of Oxygen, and despite continually testing negative for Covid, they were trying their best to shoehorn me in to that diagnosis, discussing Remdesivir (which I flatly refused) and were talking about bringing in a Pulmonologist (measuring me for a ventilator, which I was pretty sure would kill me).

For two days, I begged my physicians to take me off Eliquis, and put me on Indomethacin, which led to lectures and stern recriminations from said physicians.

Three days in, I spit out my nighttime dose of Eliquis, and the next morning at around 4 AM, surreptitiously took a dose of the Indomethacin from the prescription bottle my wife had put in with my bag of personal effects.

Within two hours of taking the Indomethacin, my non-supplemented Oxygen levels were consistently above 90%. I informed my nurse of the improvement (although I did not mention the Indomethacin). She took me for a walk around the ward with an oxygen monitor on my finger to confirm, and I was discharged within a few hours.

I went home with a prescription for oral antibiotics, and remained (of my own accord) on Indomethacin for a total of 5 days.

I want to make clear, I do not recommend this for anyone!

One curious thing. This was late August and between late August and mid-late October, my somewhat low Hemoglobin levels had dropped from the mid 11s to the the low 8s, and Iron levels which are normally above 20, were practically non existent. I have since received Iron infusion therapy and am feeling much better.

Jus to be sure it was not due to a GI bleed of some type, I underwent a Colonoscopy, and Upper GI endoscopy, which basically turned up nothing beyond some diverticula, and a small hiatal hernia.

Thanks Mar. Feeling much better! Happy Holidays, and Merry Christmas to all who celebrate!!!