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Hi SShady43,
Mesochem supplies meds without a script.
It is very difficult to find a doc in UK who will give you a script although Alsdad did find one and posted details here on another thread. I can only add that in my personal experience the UK docs will just give you a dose of deep depression from dealing with them, which is the last thing a person with hepC needs. I have come to the conclusion that not only are they backward, the whole system is mediaeval, worse than you could expect in India or many countries which they arrogantly dismiss as 3rd world, like they dismiss the generics. If you don’t want to feel suicidal (or homicidal) then don’t have anything to do with them.
If I were looking for a script then I’d ask Doc Freeman’s advice.
Good luck
dointimeHi Rlh,
If I read you right, I think you are getting confused between previous treatment with a NS3 protease inhibitor and previous treatment with sofosbuvir and an NS5A.
Leftover NS3 variants do not influence the outcome if you are doing sof/dac tx.
NS5A variants do, either baseline or leftover, and were identified as a major cause of relapse in the Harvoni trials.
I don’t know if dac copes better with NS5A variants, that would be a question for the doc.
Good luck,
dointimeDr Freeman,
I think the idea of an ‘independent testers’ facility is excellent, in fact it could be the last piece of the jigsaw puzzle necessary, not just for doctors but for anybody wishing to buy and use the generics with confidence. With 2 generic Harvoni’s in Bangladesh and no doubt more coming, the ability to test them is needed yesterday.
Best wishes,
dointimeHi klhilde,
If you are going down the Bangladesh route I heard that Beximco Pharma are also doing a generic Harvoni. Contact is Badrul. Email is:
bas@bpl.netBut – as you are now in Bangkok anyway (I think), why not just fly down to Tasmania and let the good Dr Freeman sort you out. Seems a helluva lot easier to me than either Beijing or Dhaka.
Good luck,
dointimeThanks for explaining that for me Sean. You could also email Rachel at Mesochem and ask her what she knows about mailing the APIs to Ireland.
Personally, I don’t fancy carrying sachets of white powder through airport security, especially with an Irish passport. I have an Irish friend who never fails to get stopped, just cos he’s Irish it seems to me. So even if what you are doing is perfectly legal, do you really want to have to prove it at airport customs control? If you do decide to travel then why not consider going via Scotland, not London. There are some good airlines serving Scotland now which go directly east, not via London.
Whatever you decide, good luck,
dtHello Sean,
Maybe you could return with the meds to the UK where they ‘should’ allow 3 months of prescription meds through, preferably with a prescription to prove it is for your own use. From there get a bus / boat over to Ireland.
If you know somebody in UK willing to let you use their address, it ‘should’ also be ok to get the meds shipped in via UK where you could pick them up.
Have a look at the Buyers Club here, (go to getting treated, how to do it) which may save you a trip to Beijing.
Good luck,
dointimeI am attaching the report for Sovaldi, similar to the one attached by Alsdad for Daklinza. See Section 2.2.3.
Alsdad, or anybody – do you see anything there that might make a difference for the encapsulation of Sof, compared to Dac?
Thanks,
dointimeAttachments:Hi Sirchinenge
What are you going to receive from Dr Freeman? The Mesochem meds already tested and encapsulated?
Also, do you have to be a registered patient with Dr Freeman – and get his prescription presumably – in order to buy direct from him?
Thanks,
dointimeHey panamajo
Good for you. I was having a little private bet with myself that you would. I know that you were in a hurry to treat.
One of the things I like about the Mesochem option is that it goes straight from the hands of Mesochem into the hands of Fedex. While that is not a guarantee of supply line integrity, it’s better than the India option where you get it from the hands of a distributor and who knows where it’s been before that on its way from the manufacturer. I mean, not that you can’t find a trusted Indian supply, just that you need a little more faith.
Best wishes for your tx. Please email me anytime, let me know how you’re getting on.
dointimeHi Archer,
Here’s something on that:
http://www.clinicaloptions.com/Hepatitis/Treatment%20Updates/HCV%20Resistance%20Alert/Clinical%20Thoughts/CT1.aspxdt
Well it’s true. A lot of them are. I’d like to think that some of them are not.
I get the impression that at my NHS clinic there’s a few different things going on. Firstly, they are not very well informed about the world of HCV generics. Seeing as things are changing every day I can understand that. Secondly, they’ve been at this for a long time, decades, and they know what can go wrong, so their caution is understandable too. Lastly, the individuals running the clinic are hogtied by directives from above. They might have some leeway at their discretion but they can’t disobey direct rulings.
I think you have to look at the top , the BMC (British Medical Council) to find the people putting out the directives. If I were Big Pharma that’s where I would go to ‘influence’ matters. Then there’s the NHS heads, as thick as thieves with their health ministers, each pretending to be horrified and wholly ignorant of what the other is doing. Good cop, bad cop.
And there are consultants like yours who choose not to exercise the discretion that they have. It’s a bad show.
dtI couldn’t agree more! During and after my last stint on ifn I felt like I’d been run over by a Mack truck and it took a long time to get out of that hole. I am excited too by people telling how they feel rejuvenated so quickly after starting treatment. Bring it on!
dtThat’s funny. I have fantasies about doing the same thing. If we are not the only ones then there could soon be a rash of people arriving at their NHS clinics appearing to be ‘mysteriously’ cured. Spontaneous viral clearance could start to pop up everywhere. I wonder what they would make of it. Would serve the b@stards right, the ones who refused to help us.
dt
I should add that my NHS specialist is actually a really good doc who cares. He did agree to monitor me on the NHS if I got the Indian generics, but writing me a prescription was a step too far.Oh, ok.
I’ll tell you where I’m coming from. I think that there is a really good thing happening over there where you are. That message needs to get out and is getting out. But what is most likely to discredit it is if the messengers over-egg the pudding. I’ve seen some claims which have made me cringe (not talking about you here) and I fear might have made others run for the hills. That’s bad because there is so much of value being offered that is helpful, and that will be missed.
So, good news stories and positive thinking, great. I love fairy tales too, but they have their place.
dt
Hi Em,
Do you have the liver fibrosis score for any of these people from before and after their treatments, as shown by fibroscan or biopsy? Liver function tests alone are not enough to tell us about the extent of liver scarring that there is. I am not prepared to believe that a shrivelled, lumpy cirrhotic liver can regress back to the state of a nice soft elastic unscarred liver in 12 weeks. I would love to be proved wrong about this.
dt
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