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  • 21 November 2015 at 8:11 pm in reply to: Can hep C cause strange symptoms? #4369
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    • Guardian Angel
    • ★★★★★
    @enkel

    Hi 2b,

    You may be right but what it relates to this thread?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    21 November 2015 at 3:42 pm in reply to: Can hep C cause strange symptoms? #4356
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    HCV affect directly and indirectly the nervous system. Anyway this is not a concern anymore. Cure is there.

    Chronic infection with hepatitis C virus (HCV) is associated with a wide spectrum of extrahepatic manifestations, affecting different organ systems. Neurological complications occur in a large number of patients and range from peripheral neuropathy to cognitive impairment. Pathogenetic mechanisms responsible for nervous system dysfunction are mainly related to the upregulation of the host immune response with production of autoantibodies, immune complexes, and cryoglobulins. Alternative mechanisms include possible extrahepatic replication of HCV in neural tissues and the effects of circulating inflammatory cytokines and chemokines.

    http://www.hindawi.com/journals/jir/2012/236148/

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    18 November 2015 at 7:41 pm in reply to: My twinvir story #4197
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    How you feeling Tweakmax?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    17 November 2015 at 1:52 pm in reply to: Young J the dragon slayer #4118
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel
    CJ wrote:

    Hi Enkel,
    Thanks & the answer is NO he says he feels nothing!! except a bit more alert :)
    He seems a bit less “moody” to me, smiling more.
    His VL ( viral load) was 2 million, so not much different from yours, really.
    Mine got up to 19 million at one time, it can fluctuate a lot I think.
    When do you start tx?
    x

    I hope start soon. Do you have any symptom from hepc? Did you started for yourself the treatment?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    16 November 2015 at 10:23 pm in reply to: Hepcinat LP #4057
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    Hi Dan,

    from parvez,

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    16 November 2015 at 10:11 pm in reply to: Hepcinat LP #4054
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    it should be a mistake, 2016

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    16 November 2015 at 10:08 pm in reply to: Hepcinat LP #4052
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    Early december 2015 is for sure. I would say that indian harvoni is not better that Twinvir.

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    16 November 2015 at 9:55 pm in reply to: Hepcinat LP #4050
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    No Dan,

    Twinvir is the best option.

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    16 November 2015 at 9:09 pm in reply to: the patient poodle #4048
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    How Sof/led or sof/dac may affect nervous system which creates the tinitus?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    16 November 2015 at 6:55 pm in reply to: Young J the dragon slayer #4045
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    Let us know the results of your son.

    Really no sides at all? No disturbed sleeping from meds?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    13 November 2015 at 11:34 pm in reply to: My twinvir story #3900
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    How you managed with diahrea?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    12 November 2015 at 9:31 pm in reply to: Resistance and Treatment Failure – Mechanisms #3760
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    What if one relapses after treatment with sofosbuvir + DAA, does it create resistance for a second treatment with sofosbuvir 24 weeks?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    12 November 2015 at 12:03 pm in reply to: Incepta’s Virodacla #3722
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    No, It is on Hepatitis Bangladesh facebook

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    11 November 2015 at 10:21 pm in reply to: Incepta’s Virodacla #3696
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    virodacla.jpg

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

    11 November 2015 at 9:20 pm in reply to: My twinvir story #3694
    Avatar photoEnkel
    • Guardian Angel
    • ★★★★★
    @enkel

    which is the best time to take twinvir? morning or evening?

    Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
    Started Twinvir 12/12/15.
    Two weeks
    ALT 17 at 2 weeks
    Viral Load UND at 2 weeks
    ALT 13.5 at 7 weeks EOT
    ALT 10.5 at 15 weeks EOT
    ALT 13 at 27 weeks EOT, VL UND, Cured

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