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I wouldn’t be so quick to dismiss this medication out of hand RHF. To do so, I believe, would be a mistake.
Obviously, chlorcyclizine is an over the counter antihistamine used routinely for hay fever, and seasonal allergies, and has been used safely for decades for this purpose. So, I’m not really that concerned about its already established safety record.
The question I find myself asking is “If this medication is as cheap, safe, and effective (against HCV) as the initial research indicates, why wouldn’t we look at adding it to the existing arsenal for use in conjunction with DAAs?”
I yield the floor.
Coral, what a gut punch. Hurting for you…. Thankfully, you are here where you have the best team and options in the world. Thank God for that.
Know we will stand with you in fighting this beast. We will always be here for you, and with you – until the dragon is beaten and gone.
The type of predatory pricing we see with drugs like Sovaldi and Harvoni is a major factor in ‘Obama Care’ (our US quasi public health insurance system) coming apart at the seams.
US Insurers are taking in more money than ever before, and US citizens are now forced to purchase insurance or face steep fines. Big Insurers were drooling all over themselves at the prospect of creating and benefiting from a completely captive market – until reality set in.
Now the Big Insurers themselves are ‘opting out’, leaving the Obama Care exchanges in droves and running over one another to get to the exits
Realistically, some of the decline in Gileads sales is likely due to the loss of Insurers which have already left the Obama Care exchanges. However, with insurance rates now skyrocketing between 20% and 30% per year, the number of Americans who can afford the non-subsidized rates is relatively small compared to the vast majority of Americans who are now trapped within the taxpayer subsidized Obama Care scheme.
Market forces will most likely eventually bring the entire system crashing down (wheels falling off, crashing an burning, completely derailed). The endgame for the current administration is to create the circumstances for the collapse of private healthcare so that the entire system can be scrapped, and replaced with a European style ‘single payer’ government run system.
So RHF, eventually the US Goverment will “come to the rescue” – to solve a problem they custom engineered to begin with. In the meantime there will be a great deal of unnecessary pain and suffering, and a lot of Americans caught up in this political quicksand will die.
None of this is anything we the ‘little people’ have any control over at the macro level right now. The best we can do for ourselves and our fellow citizens is to look out for our own well being, and spread the word about generic DAAs as quickly and effectively as possible.
That would be nice, but with the rate of infection climbing steadily – they’ll likely hang on to that margin until hell freezes over, or the wheels fall off.
Remember that while insurers are now required by law to cover everyone in the US, Big Pharma is not constrained in its pricing. The rate of seriously ill will continue to climb, and Big Pharma will continue to milk that curve for every last penny.
My experience has always been that it doesn’t matter how good a product is if no one can afford to buy it. That 20% drop in sales tells me that fewer people are being treated, and probably the net death toll from HCV will rise by a similar percentage as a result.
You could almost infer the direct cost of greed in human lives lost with that number.
Have a nice break, Ariel! You’ve earned it. See you when you get back
I’d say having Oral Thrush is evidence enough.
Thank you for sharing this with us Ariel.
Someone reading this will be helped by your experience, and I am grateful that you shared it with us.
Thanks RoH, Meg, Sven.
Edit: I had actually written something else here, but it was really just repeating information that had already been posted, and plowing ground that had already plowed.
Over dinner the totality of what this disease has done to my life hit me like a ton of bricks. Posting the photos and looking at them in context put it all in perspective. This is a brutal disease.
Pretty serious….
We are taught to think of HCV as something that just affects the liver – but clearly, its effects are far more devastating than than just liver damage – which is terrible all by itself. In my case it has been literally killing me piece by piece.
I thought long and hard about posting this stuff because it is very personal to me. DAA treatment came along a bit late to save the natural joints I have lost, but now the tables have turned. With the help of these life saving generic DAAs, I am killing the disease rather than the other way around.
Meg wrote:Bring the surgery photos on Fitz!
OK – Here goes:
Normal spinal cord cross section ^
Severe stenosis ^
Total Hip Replacement (THR) incision^
Left hip (resurfaced) ^
Right hip (Total Hip Replacement)^So – stuff that Hep C does to the body. If anyone reading this is still on the fence, my advice is: “Do not wait. Get treatment as soon as possible.”
24 July 2016 at 10:36 am in reply to: Italy – on the path to open the gate for HCV generic drugs #21316Yes, quite right Rohcvfighter. Other than not ordering the viral load test, and ‘offering’ to take me off treatment when I persisted, my GI doc has been stellar.
You make a good point about ultimately being left to our own resources with this. I like the Viking analogy as well.
Now, who wants to see surgery photos?!
I’m sure Dr James will have some excellent input on the cholesterol numbers, Meg. Hopefully, just a passing blip on the screen. I do see that your Cortisol number is down. Not a doc, but I do know that Cortisol is a stress hormone and lower is good, so you are apparently doing a great job at keeping you stress levels down. Good for you, and for your heart!
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