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  • in reply to: Finally EOT (again) #25433
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    • Guardian Angel
    • ★★★★★
    @fitz

    Congratulations on EOT Coral. You’re quite awesome, and it’s a privilege to share this triumph with you!

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    • Guardian Angel
    • ★★★★★
    @fitz

    Honestly, we don’t know what will happen next with public health care. But, one thing is certain. If you have Hep C, the time to treat is now!

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    • Guardian Angel
    • ★★★★★
    @fitz

    Interesting premise, but I think its a bit premature to read the tea leaves that way yet.

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    • Guardian Angel
    • ★★★★★
    @fitz

    Post SVR – Higher blood pressure- resolved with Lisinopril. Completely unexpected.

    Shoulder problems – first left then right. Same exact symptoms. Decreased range of motion.Pain when rotating shoulders. Severe, and then resolving. Was so bad I was thinking it would be like my hips in past years – requiring replacement. Then (to my relief), it just subsided and went away.

    Past experience with that kind of pain was that it was permanent, and irreversible. Not so this time – so far – fingers crossed.

    At the same time went through a period where I was easily winded. Hip joints (both replaced) were clicking after walking 1/4 mile or so. That has since resolved.

    Energy took a dip at 8-12 weeks post EOT. Thought I was relapsing, but tests were negative for HCV. Energy has since improved. No longer feel ‘winded’.

    My impression is that there may be a period of increased inflammation after completing DAA therapy. Perhaps my immune system adjusting to the ‘new normal”.

    Whatever the cause, my impression is that it takes a while to return to normal. Even after the virus has been cleared, returning to normal is a process, rather than an ‘event’.

    in reply to: Ariel takes the Plunge #25112
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    • Guardian Angel
    • ★★★★★
    @fitz

    Thanks for your gracious and kind invitations Beaches and Ariel. I would love to visit OZ and hope to see you both there someday. Was definitely kidding about sofa surfing though ;) I did more than a fair amount of that while traveling in my 20’s, and these days I stay in hotels.

    The offer to cook breakfast stands. I do make a hell of an omelette!

    I hope both of you will come visit us in the states as well. Our corner of the US is great place to hang out, lots of culture, wild west and otherwise. We love company, and we’ll feed you and show you around!

    in reply to: Ariel takes the Plunge #25068
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    • Guardian Angel
    • ★★★★★
    @fitz

    Love it! Thanks Beaches #love . I’ll make breakfast for ya’ll.

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    • Guardian Angel
    • ★★★★★
    @fitz

    Edited.

    in reply to: Ariel takes the Plunge #25027
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    • Guardian Angel
    • ★★★★★
    @fitz

    Can I sleep on your couch? That’s my budget these days :lol:

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    • Guardian Angel
    • ★★★★★
    @fitz
    Gaj wrote:

    ’Intellectual Property’ isn’t about innovation or creativity. It is the second word in the phrase which clearly defines what it is about. Ownership.

    We’ll have to agree to disagree on this. As an artist, Intellectual property has kept food on the family the table. No question.

    Generally speaking, and I have a great deal of experience in this area, any original idea or expression which has a commercial value or application will be copied.

    Intellectual property laws exist to protect originators from those who would profit from the fruits of honest and arduous or inspired labor without paying a fair amount to the originators for their contribution.

    Also generally speaking, the royalties to the creator of an intellectual property are typically a fraction of a percent to 5% to 10% of sales for mass distribution of the intellectual property.

    Typically IP royalties are negotiated between IP owners and the IP distributors through their attorneys.

    So, taking $11 Billion patent cost as a starting point, theoretically 12.1 billion plus 10% ongoing royalties on bulk sales to the patent owner would be a fair amount based on precedent.

    One could reasonably negotiate and add in promotional, insurance, and other expenses to the equation, but the formula generally remains the same.

    Presumably (allegedly), when Indian manufacturers negotiate with Gilead, pricing for domestic Indian markets are predicated on some version of this formula.

    I have to think if Gilead can make a reasonable profit in India at $850, an unrestricted, unregulated, and unquestioned price of US$ 84,000 in the US, and in other ‘first world” countries is not only criminal, but deliberately genocidal.

    in reply to: Ariel takes the Plunge #25019
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    • Guardian Angel
    • ★★★★★
    @fitz
    Ariel wrote:

    Dear peeps
    Thanks for reading and supporting my statement about getting tx asap and about how easy and professional this ordering and treating business is.
    The last three days have been great for surf and I have paddled every day in a row which is remarkable because well, if you could see the carcass that I was from peginf and how hard I have had to work to rebuild what was left of me and my life.
    I’m a cheerful person whose profession was robbed by peginf riba for no reason at all and I have got through all this time. I’m private about my old status because of my career. And I am a mum of adult kids.
    Anyway
    It’s up to you
    At the end of the day we need to become our own messiah in this game of Russian roulette

    So here’s some pretty pictures of our changeable Summer waves and weather anyway to celebrate freedom
    PS I still need naps
    Ariel

    Ahhh! I want to be there right now. Toes in the surf, warm breeze, washing over me, a cool beer in my hand – watching the surfers riding the tide…

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    • Guardian Angel
    • ★★★★★
    @fitz

    We not only need to look at how we in the US treat and regulate pharmaceutical patents, but also how we define fiduciary duty for a publicly (or even privately held) corporation which actions and policies, and intellectual property holdings have such a grave bearing on public health and well being.

    The concept of fiduciary duty for a company that makes cogs and sprockets, and for a company that trades in lifesaving cures which may directly affect the survival of hundreds of millions of people should be very different.

    The sprocket and cog company should be free to charge whatever the market will bear to maximize profits for shareholders. Free enterprise! I’m all for it.

    However, a company which trades in building and maintaining the very foundations public health has (or should have) a very different duty, and that is to deliver a product which provides maximum benefit to the greatest number of health care consumers possible in exchange for a healthy margin proportionate to larger the market it serves.

    What is missing in the current predatory Big Pharma pricing strategy is any sense of stewardship or public responsibility.

    No one has ever published the numbers – but if one has half a brain, the Big Pharma formula for creating and maintaining absolute maximum profits is simple. “Keep the price of the product as high as possible, and the profits (they call them ‘pipelines’;) flowing at full capacity by ensuring through prohibitive pricing that the rate of infection outstrips the rate of cure – ad infinitum.

    If I were a betting man, I’d be shorting Big Pharma about now, and Gilead would be first on the list.

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    • Guardian Angel
    • ★★★★★
    @fitz

    The problem is – for obvious reasons – Big Pharma would like us to believe that all intellectual property is equal. Nothing could be further from the truth.

    No one ever died for lack of a licensed copy of a Led Zeppelin CD, or because they couldn’t afford the latest version of Microsoft Windows 10. People are dying every day because insurers, health care providers, and individual patients simply can’t afford to pay the extortionate pricing required for lifesaving medications.

    There are now round the clock public service ads from the US Centers for Disease Control urging baby boomers to get tested for Hep C (paraphrasing here) ‘before it is too late’. The irony is, that once tested most won’t qualify for treatment.

    At what point does abusing one’s intellectual property rights to extort the public become outright murder? Even genocide? The answer I believe is clear. It happens on a massive scale, every day – and no one so much as lifts a finger, or bats an eye.

    The rare exceptions are right here. We – at FixHepC – as group have refused to accept decline, illness and eventually death in mindless deference to insatiable corporate greed.

    The nature of pharmaceutical patents can be redefined – at any time. Any country which collectively chooses to do so can define the way it treats pharmaceutical patents. Take China for example… or now Moldova, or Bangladesh, or Egypt. Or the US after January 20th 2017 (that is only a hope at this point).

    There is also precedence for Eminent Domain in the public interest. To my knowledge it has never been applied with regard to intellectual property, but what better case than a drug like Sofosbuvir which one could easily compare to Penicillin, or Polio Vaccine.

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    • Guardian Angel
    • ★★★★★
    @fitz

    Realistically, prices will not change from Gileads side unless the intellectual property is literally taken from them, either by changing pharmaceutical patent laws to a much shorter expiration (this will also force innovation), or simply ‘commandeering the patents in the public interest through Eminent Domain.

    What has happened in the US, and throughout the world is that taxpayer, and citizen bank accounts have been hijacked by Big Pharma via the public health mandate. The fundamental problem is not the insurance companies, or exchanges, or what ever you call it where you live. It is what the insurance company and ultimately the consumer is forced to pay for.

    Any answer to more affordable public/private health insurance must come fundamentally from pharmaceutical price reform, or more to the point – by bringing Big Pharma patent and price abuse to a drop dead halt.

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    • Guardian Angel
    • ★★★★★
    @fitz

    Tariffs and deregulation are sole and separate items.

    Deregulation opens up the market to competitive pricing. Tariffs simply level the US domestic playing field for US companies to compete with offshore manufacturers who have the advantages of lower labor costs, less environmental regulation and the associated costs, and currency manipulation (e.g. Yuan/US$ Exchange rate).

    So, if Irish manufactured Sofosbuvir (with tariffs) beat U.S., Indian, Bangladesh, etc. Sofosbuvir pricing, then insurance companies and health care providers would be free to buy Irish Sofosbuvir. US pharma manufacturers who have become fat and lazy though a captive market guaranteed by their bedfellows in congress and previous administrations would necessarily have to become more efficient to compete with the lowest cost suppliers, domestically and offshore – with a little home court advantage (within the US) to ensure they tend to stay home and don’t head to Ireland or Bangladesh to manufacture.

    Additionally – what is being contemplated are selective tariffs which specifically target US companies who move production and jobs abroad in order to sell their products back to the US at a higher profit. In a ‘carrot and stick’ scenario, selective tariffs, and selective is the key word, are the ‘stick’.

    The ‘carrot’ is a lowering of US corporate tax rates (currently among the very highest in the world) to among the lowest in the world to attract new capital, repatriate capital currently held offshore, fuel domestic economic growth and allow US companies to be more globally competitive.

    Regardless of tariffs (unless they turn out to be ridiculously high) competition will drive prices downward – everywhere.

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    • Guardian Angel
    • ★★★★★
    @fitz

    Gaj wrote:

    “Thanks Fitz,

    3. Charge 20% – 35% tariff for US originated medications imported from abroad. [/code]

    Wouldn’t this “raise prices, not lower them”?

    For the high end patented medications for which Big Pharma is currently getting extortionate prices, and even for the off patent ‘generic’ drugs currently available in the US domestic market — provided the US market were deregulated, and pharmaceutical manufacturers worldwide are allowed to compete – not on the ‘grey market’, but head to head in the US market – the answer is a resounding NO!!! Prices overall will drop very, very quickly.

    Every manufacturer in the world wants a piece of the US market, tariff or no tariff.

    Let US insurance companies and US health care providers buy quality pharmaceuticals in bulk from the lowest bidder, and you’ll see pharmaceutical prices everywhere drop like a rock.

    If a 20% to 35% advantage isn’t enough to keep US pharma companies competitive (and it likely is) – Sayonara boys, don’t let the screen door hit you in the ass on the way out!

    Also, a US tariff would affect only pharmaceuticals imported to the US, and worldwide price competition would apply downward pressure on pricing worldwide – so I think that would be a ‘win’ for everyone.

Viewing 15 posts - 31 through 45 (of 490 total)