Entirely insignificant. It looks like you were slightly dehydrated when the blood was drawn but these numbers change a bit from day to day, and in fact you get different reading in the morning and at night….

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545081/figure/F1/

“Well,” said Pooh, “what I like best,” and then he had to stop and think. Because although Eating Honey was a very good thing to do, there was a moment just before you began to eat it which was better than when you were, but he didn’t know what it was called.”

Actually with the greatest of respect to Pooh there is a moment after eating honey that is better, and it already has a name….

SVR

And your time starts from….whenever you choose.

Be a rebel. Do it. Open the bottle. Take a tablet. Put it in your mouth. Swallow.

Exactly what value is any other person going to add to the process?

No == don’t do it == Don’t get cured
Yes == do it == Duh? And I just paid 200 quid for you to state the bleeding obvious!
Maybe == WTF

Once upon a time I was doing my first free fall skydive under the tutelage of instructor, Captain Ron Llywelyn (ex SAS) .

In the days before tandem you learned to skydive like this:

1. Jump out of the plane on a static line x 2
2. Jump out of the plane on a static line, until you manage 3 x in a row “dummy ripcord pulls”
3. Then do your first free fall

Now a dummy ripcord pull is hilarious (in retrospect) in that you pull the handle and out comes a little flag showing your jumpmaster you did it but rather like the Wile E Coyote in the Road Runner cartoon having a WTF moment before splattering into the ground.

[video]https://www.youtube.com/watch?v=Hd755bbc8uw[/video]

Anyway getting onto the moral of this tale….

I asked Capt. Ron this question:

“Hey Ron, so how long do I have to pull the ripcord?” (expecting the answer 15 seconds which is true for a free fall from 3,500 feet)

But he said this…..

“Well James, I’ll tell you. You’ve got the rest of your f***in life to pull that ripcord”

Good luck LG. I’ll look forward to reading your posts.

Cheers
Lynne

Remember the half life of Ribavirin is about 12 days so it takes 12 days to drop to 1/2, another 12 to drop to 1/4, another 12 to drop to 1/8 of the original ie expect it to take a couple of weeks to come good when you stop.

You may be interested in this (which is from our decision support tool) Look at the f4: and fail: sections and you will see the SVR rates for 24 weeks with/without Riba from ION-3)


sof_led: {
default: 97,
rating: {
aasld: ratings.classILevelA,
easl: ratings.A1
},
gt1a: {
default: 97, // ION-1 98% (142/145) ION-3 96% 96% (165/172) Aggregate 96.8% (307/317)
rating: {
aasld: ratings.classILevelA,
easl: ratings.A1
}
},
gt1b: {
default: 99, // ION-1 100% (67/67) ION-3 98% (43/44) Aggregate 99.1% (110/111)
rating: {
aasld: ratings.classILevelA,
easl: ratings.A1
}
},
f4: {
default: 97,
rating: {
aasld: ratings.classILevelB,
easl: ratings.B1
},
w12: 97, // ION-1 97% (32/33)
w12riba: 100, // ION-1 100% (33/33)
w24: 97, // ION-1 97% (31/32)
w24riba: 100 // ION-1 100% (36/36)
},
fail: {
default: 94,
rating: {
aasld: ratings.classILevelB,
easl: ratings.B2
},
w12: 94, // ION-3 94% (102/109)
w12riba: 96, // ION-3 96% (107/111)
w24: 99, // ION-3 99% (108/109)
w24riba: 99 // ION-3 99% (110/111)
}

},

There is very little statistical difference between 11 and 12 (<10%) so given you're symptomatic and with or without Riba you are looking at an SVR of 97-99% I would be inclined to stop now.