Hello wrightjw198034,

Sadly, yes, there have been patients who have failed the treatment. If you treat over 3000 patients, and we have, and the cure rate is 95% that dictates there are 150+ patients who failed the first round.

To make matters worse cure rates for GT3 are lower than for GT1 or GT2. That said, the odds are still very good – > 90% where exactly how much better depends on level of fibrosis, ribavirin and duration of treatment.

An easy way to put your mind at rest is to test your viral load – chances are this will be undetectable after 4 weeks. See https://fixhepc.com/link2labs for a < $100 source of PCR testing. It's not unusual to have very few side effects. The usual major "side effect" is feeling better rather than worse.

Hi Paul,

Yes it is possible to be cirrhotic with few symptoms.

With GT3 and cirrhosis you must have ribavirin with the Sof/Dac. You should also have 24 weeks treatment.

For GT3 cirrhotics Sof/Vel for 12+ weeks (and preferably with riba) is the best 1st line option.

Hello tototo,

Sorry to hear you seem to be having a bit of a hard time with the medication. While it’s unusual it does happen. You may find increasing your fluid intake and trying some vitamin B12 help matters.

Usually, we see thing settle down during the course of treatment as the virus is removed.

It does sound like side effects related to the Maviret, so it might be best to take it just before bed, that way you will (hopefully) sleep through them (and the tiredness you get 3 hours after will be hidden during sleep).

Hello 808cruiser,

2-3 million is the average.

People have higher levels when their immune systems are not doing much. While this might sound bad, the damage from Hep C is driven by the immune response. The little critters don’t eat much, so, curious as it may seem, people with a viral load of 10 million are often a lot healthier and less damaged by the Hep C than people with a viral load of 10 thousand where there immune systems are working hard to get rid of the virus and killing lots of liver cells in the process.

Anyway 4 weeks after you start treatment you will have < 15 ...

Welcome Robert,

It’s great to have you here. On the good news front, GT2 is the pick of the bunch in terms of cure rates. Even the old Sovaldi+Ribavirin managed 97% but Sovaldi+Daklinza (the cheapest generic), Epclusa (also available as a generic) and Maviret (no generic) all do an even better job of getting rid of it.

You should definitely chase insurance funded medication, but if you can’t get that generics that do the same job can easily be sourced and delivered into most countries around the world.

Good luck with the CT, hopefully that will show your liver is still in pretty good shape so once we get rid of the virus you can expect some significant health improvements.

Hello Kaju,

It does sound as though you have borderline diabetes. Patients with Hep C get diabetes at 2-3 times the rate of people without Hep C – as to why, nobody really knows.

It’s probably related to the Hep C and or the treatment, but probably would have happened without treatment.

We do see it more commonly in people who are overweight and notice that people who shed excess weight often have their blood sugar improve. It also occurs (less commonly) in adults in the normal range.

At the moment, it’s probably just something to keep an eye on. How tall are you and what do you weigh?

Hello michael13,

In Australia Baclofen 10mg x 100 is $14.39 AUD which is $10.20 USD. To access that you would need an Australian prescription which can be gotten online from https://gp2u.com.au/

So, really, the major cost is going to be the prescription ($50-70) and the freight ($50). You are stuck with the freight regardless of where it comes from.

What does it cost in the US?