Forum Replies Created
-
Oops, sorry! It appears that my attempt at self depreciating humour was misinterpreted.
I fully agree and support the importance of good diet and exercise during treatment to the extent that I have been able to adjust my favourite belt in by several holes and bought half a new wardrobe since commencing treatment. In recognition of the impact on my health and lifestyle I fully intend to continue the process into the future including after achieving SVR.
I have always eaten reasonably well in the past but often too much and while I quite enjoy exercise in the right situation I can be a lazy bastard if I allow myself and/or the weather is inclement (or too nice) thus the aside about “rather be doing”.
(NOT) Gaj’s approved training program.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Sven,
This is a cryogoblin.
Sorry, I’ll let Fitz explain cryoglobulins and cryoglobulinemia.
PS per your edit, there can never be too many questions except when they are from a two year old after they kept you awake half the previous night.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Split,
Sorry to hear your diagnosis. To clarify my previous statement, I was trying to say that weight while relevant isn’t the defining point with NASH in case someone read this thread and thought “oh, I’m not overweight….can’t happen to me”. Losing excess weight will certainly help but it is also about improving your metabolism so there is less tendency for fat to accumulate in your liver. See my comments about a good diet and plenty of exercise.
Many G3s do have NASH at some level (I was careful to qualify comments about myself with the words ‘apparent’ and ‘seems’
but the majority do clear HCV with DAAs, just not quite as many as other genotypes. Here is some further reading on fatty liver and HCV: http://hepatitiscnewdrugresearch.com/fatty-liver-and-hcv.html
Good luck with the diet and excercise, neither of which are really at the top of my list of “things I’d rather be doing”
and best wishes for the next round of treatment on which I suspect we may be fellow travellers.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Great news on both counts Fitz!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Price,
As you say, steatosis (fatty liver) is more prevalent in G3s. It certainly should be considered by anyone with this genotype.
My specialist told me a couple of years ago that it isn’t apparent in my case and my liver seems to be within normal range. On the other hand I do tend toward high serum triglycerides and we don’t really know what I’d be like in the absence of HCV. A good reminder to check current status with him next appt.
Splitdog,
It’s a little more complicated than just being overweight. Steatosis is retention of fat inside the liver cells, being overweight certainly doesn’t help but it can occur even in skinny people. It’s mostly about how your metabolism works. Along the lines of what you eat and how you process it rather than how much you eat.
I believe a good diet, plenty of excercise and aiming for a healthy weight will all help. I won’t suggest diets as there are others more qualified but think lean, mean and lots of energy rather than skinny, starving and weak.
(Lean and mean is a bit of an ask for me these days but I try
)Edit: note to self – must type faster. Thanks LG.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Nice! What a clever way to help spread awareness.
You: “What’s that bracelet you are wearing?”
Me: “Oh this? Well…….”
So how do I get one?
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Congratulations Jill! It’s party time for Poodle!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi JamesF,
Here’s a link to Dr James’ comments. https://fixhepc.com/forum/questions-and-answers/622-missed-dose-worried-should-i-take-extra.html#9328
As the others say, it is a good idea to take at the same time each day so it is a habit. I took mine when I got up and used a 7 day pill box so I didn’t lose track. That always sat on my place at the dining table where my cereal bowl needed to go so I had to move it to eat meals which made it difficult to forget to take my dose. As beaches says many set their phone alarm as a reminder.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
– It is difficult to see how the opening poster (OP) can hijack a thread. The usual convention is that they determine if the thread has served their purposes or not.
– While some Internet forum have strict rules on threads moving off topic this one does not. Threads that do meander away from their original purpose can sometimes but not always lead to fruitful pastures.
– Participation in threads is voluntary based on your interest in the topic under discussion. Any member can start a new or offshoot thread should they wish to discuss something not/no longer being covered to their satisfaction.
– Personally I am unable to determine from people’s writings on the Internet whether they suffer(ed) from HCV and regardless that is not a requirement to be a member and participant on this site.
– Attempts to declare what HCV sufferers are interested in and are acceptable areas for discussion and what are not sound suspiciously like ‘crowd’ censorship to me. They certainly don’t speak for me.
– Below are what could be best described as this forum’s ‘Terms of Use’. Please pay particular attention to the opening sentence.
Our goal is to provide a location for a warts and all discussion of Hep C in general and DAA treatment.
While a lot of discussion is about generic DAAs people taking OEM DAAs are equally welcome.
There are many other forums discussing this topic around the world – feel free to link to any information you think might help others, including other forums.
We aim to censor only the following 3 things:
Totally unrelated SEO spam
Posts along the lines of “I can get you DAAs” where the poster has a freemail address, claims to be from say Incepta, but are not.*
Flamewars, hate speech, or serious profanity* There are some proven independent parties here and the more channels to access the better – the key is making sure would be rip-off merchants can’t find victims here. The moderators know who has been proven trustworthy and reliable.
https://fixhepc.com/forum/welcome/368-this-forum-is-censored-only-for-spam.html
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Thanks Price, very new article.
Although not able to access the full article yet, I see that 85% of them went on to acheive SVR after they had their liver transplant so presumably they became undetected? I wonder if having a compromised immune system prior to transplant was preventing them from clearing the stragglers that the DAAs hadn’t affected?
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
virus C (GBV-C), formerly known as hepatitis G virus (HGV) and also known as HPgV is a virus in the Flaviviridae family and a member of the Pegivirus genus,[1] is known to infect humans, but is not known to cause human disease
https://en.m.wikipedia.org/wiki/GB_virus_C
It appears that HGV is a benign blood borne virus, at any one time our bodies are host to zillions of such viral/bacterial/fungal life forms. The fact that it has (had) a name similar to several diseases does not make it one.
Serg
“Analogically, if HCV
willnoticeable symptoms for me – what is the reason to define such situation as a “disease”?”I have amended your statement/question above to reflect the reality that while chronic HCV is a slow acting disease that doesn’t always cause obvious damage, it is still having some sort of impact on the body. LFTs within nominal range that drop on treatment is evidence of that.
Errr….Google says that TTW is a computer game that can get infected with the SHuer3 virus??? (Take one subscription to Norton annually.
)
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Symptoms such as cirrhosis, etc. are subjective indications or signs of disease. They may or may not be present now or in the future and may or may not be due to a particular disease.
On the other hand a disease such as HCV can be defined by objective means such as a PCR test.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
No.
– Hepatitis C is the disease.
– Cirrhosis/extrahepatitic manifestations are symptoms.
– it is possible to have a disease without displaying obvious symptoms.
I’m sorry but if you believe otherwise it is not semantics but misunderstanding.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Thanks RHF, excellent points that got me thinking about other diseases that are often considered curable or cured. So I googled the definition of “cure” and found the following.
“When I use a word,’ Humpty Dumpty said in rather a scornful tone, ‘it means just what I choose it to mean — neither more nor less.”
― Lewis Carroll, Through the Looking Glass
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Thanks RHF,
In Australia while doctors often prescribe by brand name most pharmacists ask if you would like “generics if available” when you give them a script. Apparently about 40% of our prescription dispensing is generics these days.
On a personal note, my blood pressure tablets patent expired about two years ago. Since then the price of the branded product has halved but the generics are one third of the old price. Of interest is that one of the two generics that I am aware of obviously comes from the same factory/production line as the branded item but in plain packaging. So the manufacturer makes sure they get both the brand name business and a slice of the generics business.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
