Forum Replies Created
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Hi Archer,
While only mild C-P/a, I do have the experience of a couple of small HCC (so far successfully resolved) and the basic gist of what my specialist tries to tell me seems to be that clearing the virus and as a result avoiding continuous inflammation and fibrotic activity at the same time as regeneration will significantly reduce the ongoing risk of recurrences although it will require ongoing monitoring. Apparently it should also provide some improvements in the extent of fibrosis and thus cirrhosis over time as long as I look after my liver but he did say the improvement seen varies by case.
So I’m also very interested in the latest developments around optimum liver care post HCV.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Joan wrote:I also read in a post (could be the same one) that HCV can come up in blood tests for a fews years to come but the viral load will say undetected which means clear.
Hi Joan,
Yes, two different tests.
1. There is an ‘antibody’ test that just tells you that your body is saying “yes, I have met this virus and fought with it”. It doesn’t tell you whether or not you currently have the virus only that you have had it at some stage. It is a relatively cheap quick test and was probably one of the tests your doctor used (along with others such as probably hep a & b) when he first suspected that you may have some sort of liver problem.
2. Then there is the PCR test which shows via detected/undetected whether you have active virus in your body. Your doctor would have run this test once he got a confirmed antibody test to see whether you still had the virus before recommending treatment. And it is the test used to check for SVR at various points and into the future if you ever want confirmation that the virus hasn’t returned. (The V/L test is basically the same test but goes into more detail to tell you how much virus rather than just virus/no virus)
Test 1 is of little use to you as you already know you have had the virus in the past and it will show positive for many years, possibly even your whole life.
Test 2 in its basic detected/undetected form is what you need from now on as you just need to keep getting undetected or zero results to confirm the virus hasn’t returned.
And while I’m mostly feeling better than I did pretreatment it is a bumpy ride some days….but there’s light at the end of the tunnel now!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
No programmer but Past Treatment field probably needs to allow more than one choice? Eg Sofosbuvir 12wk and Ribavirin or Eg Sofosbuvir 24wk and NS3 NS4 NS5A
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
^^^^^
+1
I got a 8yo Margaret River Shiraz from a Santa I hadn’t told.
……looks like it will become a 9yo (or at least a great way to share celebrating my 60th a month after finishing treatment.)
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Dan,
As you already have HCV, scratching your eczema until you bleed won’t have any effect on you personally.
However, you need to continue to practice normal safe hygiene, the same as if you cut yourself, ensuring your blood is cleaned up, surfaces that it has been on are sterilised and the open wound is covered to avoid risk to others. Obviously, avoiding breaking the skin in the first place is preferred when possible.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Thanks Vororo,
I thought I knew a little about the subject previously but this taught me far more…….now I just need to read up on the 99% I still don’t get!
Seriously though, a fascinating video that gave me a better understanding of the theory behind NS4B/NS5A inhibitors, et al.
Thanks
GJoy, as I was watching I thought it should have some early Pink Floyd as backing music.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Congratulations and best wishes for the future. Don’t forget to let us know when you achieve SVR24.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Lynne,
Dr James posted about this in the below link. In summary “Undetected” means a zero reading in your blood. As to whether that means no virus in your system at all, I think klhilde’s post on the same page covers it well.
Great to hear you are feeling much better. It seems many of us wake early on Tx (I only got 4.5hrs last night), just try to catch up when you can.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Tina,
Great to see generics, fixhepc, Dr. James Freeman and Greg Jefferys getting publicity in New Zealand media.
Kudos to Hazel for going public with her story.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi olegiva,
Please read the below link which may be of assistance.
http://fixhepc.com/forum/daa-access/457-warning-to-online-buyers.html
I can’t comment on the price you are being offered but others may be able to.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi dt,
I assumed you meant 12wks Led followed by 12wks Dac for a total of 24wks Tx? Is that correct? You say your liver isn’t bad so is there some other reason to treat for that long? Or are you doing it to try to ensure no relapse?
If the latter is the case then I would have to wonder whether doubling up on the guidelines, with a medication change or not, was the best solution. While Sof/Led/Dac are a lot milder than previous treatments I suspect they do have some trade offs regarding their effects on our bodies as seen by the various sides people experience. I would seek expert medical advice. YMMV.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi dt,
I’m wondering if one thing that you may want to take into consideration is if you are unfortunate enough to relapse. Usually the recommendation is to use a different Tx if available. Having used the two main NS5A inhibitors previously, what would then be your best option for retreatment?
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Congratulations Nadia & Vicki!
What a great way to celebrate Xmas & the New Year.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
berrinice wrote:I have just been diagnosed deficient B12 & folic acid associated with a) alcoholism or b) leukemia
Hi berrinice,
0.38% of 60mg daily is equivalent of 1/44,000 of a standard drink so the traces of ethanol in the Dac won’t be the cause of the deficiencies. While it is associated with alcoholism the alcohol isn’t the cause. Most likely it is a dietary deficiency, are you vegan or on a low animal product diet? Regardless, your GP needs to investigate it to determine the cause. Here is some info in relation to hep c.
http://hepatitiscnewdrugs.blogspot.com.au/2011/01/liver-disease-and-vitamin-b-12.html
G
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Congratulations to you both, IRMA & Neilo.
G
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
