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Stiffness measured by Fibroscan doesn’t say too much about real liver condition. It is only scale of inflammation. So, maybe your BF doesn’t have cirhossis. Biopsy is much more representative, because there are checked liver tissues.
After treatement, when the virus is gone, liver is not eaten by inflammation, and stiffness goes down. In some cases it is quite fast process, in others take some time…
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28I don’t know how HCV works… In my case after EOT I don’t feel much better. In my opinion I feel even worst during the time I had to swallow sofosbuvir and daclatasvir pills.
My situation was quite similar to yours. I was undetected since 18th day of treatment. Additionally I got HCV-RNA test in the middle and in the end of treatement, Both were negative. I followed Doc. Freeman advise and I’ve extended my treatment to 24 weeks- F2 (9.2 kPa) and VL: 1,23*10^6 IU/ml. Today I received SVR4 HCV-RNA test: HCV virus is not detected. Now I am wait for SVR12… and whatever tomorrow brings.
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR2817 February 2017 at 4:17 pm in reply to: Abbvie ABT-493/ABT-530 gets FDA breakthrough therapy designation #25335Are these two drugs going to be produced in Bangladesh?
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28Anyway, upcoming Friday i am going to finish my 16th week of treatement (8 weeks left). I am UND since 30th August. So, the question is can I go to gym? I think about 3 times a week training, about 1 hour long each. I want to add, I feel great. I don’t have any side effects now.
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR281 November 2016 at 9:50 pm in reply to: I want to buy sofosbuvir (Sovaldi®) and daclatasvir (Daklinza®) #24122@Gaj
My data is from our polish support forum. Its verified and also placed on moderated by Greg site: http://hepatitisctreatment.homestead.com/harvoni-india.html (see “Poland” label). BTW Poland is nearby Germany And I don’t know the law in Germany. Maybe for Sven Redemption trials are the simplest solution.
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR2826 October 2016 at 9:16 pm in reply to: I want to buy sofosbuvir (Sovaldi®) and daclatasvir (Daklinza®) #24030The easiest way is to order drugs to Poland. Do you have any family in there or friends? You only need permission for drug shipment. Drugs for 12 weeks are quite cheap especially for citizen of Germany:
• Hepcinat + Natdac 60 – Natco, 700 dol.
• MyHep + MyDacla 60 – Mylan, 650 dol.
• Sofovir + Daclahep – Hetero, 620 dol.You can contact with this guy from India. he is trusted seller. His name is Vivek. Contact is placed below:
e-mail: info@medsure.in
Skype: medsurein
WhatsApp: +919096843768If you have any queastions, just ask…
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28I wonder… maybe that ‘s also genetycly detremined. For example my brother’s liver parameters are: ALT arround 10 and ASPAT arround 15. And he is HCV free. So mine, when I will be healthy, supposed to be similar.
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28Today I got my lab tests. I don’t understand one thing.
Before treatement my ALAT was equal 28, in the beginning of 5th week of treatement was 9.9 and now, in the beginning of 9th week of treatement is 5.9. ASPAT also dropped from 18 before treatement to about 10 now.I don’t know why people mostly have these two chemical parameters rised (in my case they were ok even before treatement)? I want to add that my liver fibrosis is/was F2 (9.1 kPa)…
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR288 October 2016 at 10:39 am in reply to: Summary of EASL Recommendations on Treatment of Hep C 2016 #23624This may be helpful:
http://www.easl.eu/medias/cpg/HCV2016/English-report.pdf
BTW What kind of retreatement are you going to follow now?
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28So just check ALT and ASP. If they are similar to the results obtained at the EOT you should be fine. That’s my opinion. You can always take another HCV-RNA test.
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28In Poland we get drugs from three suppliers. You can find contact to them on the website (Search Vivek or Gandhi):
http://noweleki.hepatitisc.pl/p/leki-z-indii.htmlHere is the third supplier:
http://noweleki.hepatitisc.pl/2016/08/kolejny-cennik-od-kolejnego-indyjskiego.htmlHere u have price lists (Gandhi’s list if from the end of July):
http://noweleki.hepatitisc.pl/2016/09/aktualne-ceny-u-viveka-2.html
http://noweleki.hepatitisc.pl/2016/07/gandhi-przysa-aktualny-cennik.htmlIn Poland we mostly get drugs from Vivek. I got my package within 7/8 days. Shipment is free if you buy at least 3 bottles of medicine.
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28OK. Thanks for help. I don’t have any other doubts and I am going to follow my primal idea- 24 weeks on SOF+DAC. My GT3 must be defeated.
GT 3a
Contracted: October 2008
Diagnosed: March 2009
First treatement:
VL 250.000 IU/ml
Fibrosis F0
Start: November 2010
Copegus+Pegasys (24 weeks)
EOT: VL UND
SVR24: VL DETECTED
June 2016
Fibrosis F2 (9.1 kPa)
VL 1.230.000 IU/ml
Second treatement:
SoviHep+DaciHep (24 weeks)
Start: 13.08.2016
VL UND: 30.08.2016
VL UND: 27.01.2017 (EOT)
EOT+4 weeks: AlAT 9.8 SVR4
EOT+8 weeks: AlAT 9.7
EOT+12 weeks: AlAT 7.0
EOT+28 weeks: AlAT 7.6 SVR28 -
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