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21 August 2019 at 2:13 am in reply to: Cirrhosis and Resistant Hep C – New Symptoms are they serious? #29396
Hi Barry, I checked your medications and only 1 has potential interaction with Mavyret, it’s Seroquel (Quetiapine). Potential interaction means that it will likely require additional monitoring, alteration of drug dosage or timing of administration. All the other medications have no interaction with either Mavyret or Sofosbuvir. Please see the interaction report below.
InteractionsReport2019_08_20_22_07_27.pdf
Making the world a better place – one patient at a time.
20 August 2019 at 10:32 pm in reply to: Cirrhosis and Resistant Hep C – New Symptoms are they serious? #29393Hi Barry, to learn if the new treatment you will hopefully be getting (Mavyret + Sofosbuvir) will interact with your current medications or not, there is an excellent resource where you can check and know https://www.hep-druginteractions.org/checker You have to check using the medications generic names, for example Mavyret is Glecaprevir/Pibrentasvir. If you need help, you can write a new post with the names of the meds you’re taking and I’ll check for you. If there is interaction, you will need advice from a doctor on how to handle the transition.
The modern Hep C medications (e.g. Mavyret and Sofosbuvir) are very safe and do not cause any damage to the liver or any other organs, they have been studied extensively in multiple very large clinical trials. On the contrary, they will stop and allow the body to start reversing the damage that has been done. Looking forward to hearing good news from you that you were admitted to the trial.
Making the world a better place – one patient at a time.
Congratulations Anton, that’s really awesome, enjoy life without Hep C
Making the world a better place – one patient at a time.
Really excellent work Dr James , thanks Hazel for this link.
Making the world a better place – one patient at a time.
19 August 2019 at 6:14 am in reply to: Cirrhosis and Resistant Hep C – New Symptoms are they serious? #29377Hi Barry, your email was received and forwarded to Dr James
Making the world a better place – one patient at a time.
18 August 2019 at 6:03 am in reply to: Cirrhosis and Resistant Hep C – New Symptoms are they serious? #29371Hi Barry, sorry to hear about your health situation, and good for you trying everything you can to beat this virus . Please make sure to post your blood test results when you receive them next month. To be able to help, Dr James has asked you to answer a few questions in his post above as well. Best of luck to you.
Making the world a better place – one patient at a time.
Hello MissusB , just wanted to say welcome to the forum and congratulations on starting treatment, Mavyret is an excellent drug, that’s really great. I’m sure our resident expert, Dr Freeman, will answer your inquiry soon as to why your doctor is not concerned about Hep B reactivation in your case. Best of luck to you.
Making the world a better place – one patient at a time.
Congratulations Hazel, that is awesome
Making the world a better place – one patient at a time.
I like the dramatic effect of the typewriter sound, especially with the question mark towards the end, powerful message.
Making the world a better place – one patient at a time.
Thanks for this Hazel, very impressive anti-Hep C activism going on in New Zealand, seems like the country is going to reach its goal of eradicating Hep C in the next few years. Dr James and you are definitely doing your parts
Making the world a better place – one patient at a time.
Hi Karen, congratulations on these excellent LFTs results at the 1 month mark, as Dr James mentioned, they pretty much guarantee that you’re undetected now. As you said, you need to continue treatment until the very last pill to finish off the virus, but you’re definitely on the right track of falling in the big % of people who can call themselves CURED
Making the world a better place – one patient at a time.
5 July 2019 at 3:17 am in reply to: Assigning the Hep C Butterfly Symbol to the Public Domain #29309Interesting, Marty and Dr James did a great job on the design. That tattoo looks awesome Hazel
Making the world a better place – one patient at a time.
Congratulations Hopeful, that’s really awesome, you’re definitely on the right track to beat Hep C!
Making the world a better place – one patient at a time.
Hello Karen, I’m glad that you didn’t feel any side effects at all, the modern Hep C medications are a walk in the park compared to the older Interferon based treatments. Don’t worry, the drug is working behind the scenes, most patients don’t feel any side effects either, and the cure rate is over 90%. Drinking plenty of water is key here. Hopefully it will be smooth sailing for the remaining 11 weeks as well, best of luck.
Making the world a better place – one patient at a time.
Hi Karen, welcome to the forum and congratulations on starting treatment . I understand what you mean by it being like a dream, it’s like you can’t believe you may finally get rid of Hep C. But with cure rates of over 90% with these modern medications, it will hopefully be a reality very soon.
Regarding side effects, they are generally quite mild. Hazel gave you good advice, drink plenty of water. There is reasonable coverage of what to expect in terms of side effects here: http://fixhepc.com/treatment-side-effects.html
Dr. Freeman, FixHepC’s founder, has described what to expect in a previous thread too, here is what he said :
For most people, it goes like this. For the first few days, you feel something is happening. It’s a bit like the feeling you get before you get influenza – you know, that I’m not quite right, but can’t put my finger on it.
At this stage, some people (1 in 5) will have a headache and feel a bit unwell (aching joints).
Then it just goes away. This corresponds to the drugs wiping out most of the virus.
Then most people feel better than they have for years.
About 1 in 5 people have problems sleeping, which does make people tired.
Other than that, it’s pretty much like taking any other antibiotic. Some people get an upset stomach, the occasional person gets an itchy rash.
All up, it’s generally smooth sailing, with little in the way of noticeable side effects other than feeling better.Best of luck and please keep us updated on your progress.
Making the world a better place – one patient at a time.
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