Hi Christoffer, welcome to the forum, and congratulations on starting treatment with Epclusa, it’s a really great drug . Regarding the use of Kratom with Epclusa, a previous answer in this thread by Dr James Freeman, FixHepC’s founder, states that Kratom should be avoided when treated with Daclatasvir medication, and that “it should be ok, but…” (so maybe best avoided) when treated with Epclusa medication. He also said “I do tell my patients you can’t get problems from drugs you are not taking…”. So it’s probably wise to avoid it during treatment to eliminate any doubt. It’s also worth noting that the patient in this thread also said “I felt so much better after finishing Epclusa I never bothered with kratom again”.

Thanks for the link to this excellent article Hazel, nice to see that you and Dr James are getting the recognition that you deserve.

Hello Marszab, and welcome to the forum. Please don’t automatically assume that your treatment failed because of this, when treated with the new DAA meds (such as Harvoni), having low-level detectable HCV RNA at the end of treatment does not preclude cure. Please read the conclusion of this study for instance https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834854/

To know the correct result of your treatment, you have to take the test 12 weeks after finishing treatment.

Also even if treatment fails the first time around (happens 5-10% of patients), re-treatment is entirely possible and very successful (different medications are used).

Hi Anton, congratulations on being undetected at end of treatment, that’s great. Best of luck on the SVR 12 test, the odds are very much in your favor now to reach cure. Hopefully we will hear excellent news from you in 3 months

Congratulations on your SVR 12 Maga!!! Everything looks like back to normal, that’s awesome, enjoy

That’s very good news Hotdog As Hazel said, it’s very important to keep doing what you’re doing until the very last pill.

Hi Hopeful, welcome to the forum and congratulations on finally getting treated after 22 years You must be extremely excited. Sorry to hear you’re having some side effects, the good news is that they usually last for the first week to 10 days only, and they are usually reduced to a large degree by drinking plenty of water, that’s the most important thing to do right now.

Here are a few more recommendations to follow during treatment :

1. Take your medication at the same time every day just before or with food, as it helps with the medication absorption.
2. Try to get enough rest and eat healthy (plenty of fruits and vegetables).
3. Be careful not to take any medications that may interact with your Hep C medications. This webpage will tell you about any possible medication interactions http://www.hep-druginteractions.org/checker

Additionally, the ‘During Treatment’ section of the FAQs page fixhepc.com/frequently-asked-questions.html has some more detailed information.

Hang in there Hopeful, the side effects should subside soon, especially if you drink a lot of water as I mentioned, it will all be more than worth it at the end.