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  • in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10327
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    • Guardian Angel
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    Ken:

    I think you nailed it. This is very good news.

    P.

    in reply to: medhelp.org #10283
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    • Guardian Angel
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    “Incorrigable.”

    I seriously doubt that there’s an antonym to that. I’ve never heard anyone say, “Wow, she is extremely corrigible.”

    P.

    in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10230
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    • Guardian Angel
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    Ken:
    Did you check before or after meals? Please give exact numbers? Did you check at bedtime?

    Thanks for doing this. This info will really help us figure out what happens to blood sugar during treatment and what can be done about it.

    in reply to: medhelp.org #10223
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    • Guardian Angel
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    Mike,
    You just blew your cover. Because why would you have that letter unless you were attached to the Buyers Club ?
    P

    in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10137
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    • Guardian Angel
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    Splitdog:
    No. Most of the food we eat turns into sugar. But if you eat lots of sugar then you’ll increase the fat and fat cells are insensitive to insulin.

    P

    in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10135
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    • Guardian Angel
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    Tommy:

    It’s hard to diagnose hyperglycemia when blood sugar is not being checked.

    Plus it says that in one of the studies a total of 47.2% had high blood sugar and considering that a fasting blood sugar of 123 (on two occasions) is considered diabetes, then the meds caused diabetes.

    I would love to ask the authors a few questions, like how many of them were diabetics to begin with and were the people who failed treatment diabetics or insulin resistant. I bet they were.

    in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10117
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    • Guardian Angel
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    It’s a big can of worms. You won’t be able to take meds that increase blood sugar and there are many that do. Plus having high blood sugar predisposes you to getting infections.

    And nobody will like me again because I’ll tell them not to eat chocolate and ice cream :ohmy:

    P.

    in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10113
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    • Guardian Angel
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    That’s because HCV causes diabetes.

    I preached about insulin resistance for years,
    http://www.projectsinknowledge.com/cc3/index2.cfm?id=243

    so ban me now or I’ll drive you crazy talking about IR.
    I’m thinking the Zolpidem on your cheat sheet can cause hyperglycemia.

    P.

    in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10101
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    • Guardian Angel
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    The study says the ION-3 clinical trial showed that in those who received ledipasvir/sofosbuvir for 12 weeks, the hyperglycemia rates were…..
    grade 1: serum glucose > up to 160 mg/dL……33.3%
    grade 2: >160-250 mg/dL….11.6%
    grade 3: >250-500 mg/dL …..2.3%
    grade 4: >500 mg/dL
    Those who received the medication for 8 weeks had hyperglycemia at the following rates: 21.4% (grade 1), 7.9% (grade 2), and 1.4% (grade 3).
    All patients with Grade 3 or 4 increased serum glucose had either a medical history of diabetes or glucose intolerance (HbA1c > 6.0%) at screening

    That’s worse than interferon.

    P

    in reply to: New-Onset Diabetes from Ledipasvir/Sofosbuvir #10100
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    • Guardian Angel
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    London girl:

    According to the American Diabetes Association, a fasting blood sugar above 100 gives you a diagnosis of pre diabetes, which means you’re insulin resistant.

    A HOMA obtained with a formula that uses blood sugar and insulin levels can also tell you if you’re insulin resistant.

    P.

    in reply to: medhelp.org #10077
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    • Guardian Angel
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    Gaj:
    That’s right, links are not allowed. Editing is also not allowed.
    They’re on a hepatitis board, I think they’ll think of the word.

    P

    in reply to: medhelp.org #10072
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    • Guardian Angel
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    Mine is still there.

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    in reply to: US Moderator announces our drugs are ILLEGAL #10062
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    • Guardian Angel
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    Not if you say something like….
    “I hear that the REDEMPION trials will be presented at the next AASLD”.

    P.

    in reply to: medhelp.org #10058
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    • Guardian Angel
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    Didn’t last long.
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    in reply to: US Moderator announces our drugs are ILLEGAL #10052
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    • Guardian Angel
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    That’s hilarious.

    P.

Viewing 15 posts - 166 through 180 (of 231 total)