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Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).Hi Gaj, that’s a great graphic!!
I only meant to say that Oor Wullie was going to quit arguing something that can’t be proved. And then I thought of the number of times that I cut myself with my own pen-knife when I was a kid. So your model of fighting over food around the camp fire is probably equally good, until Mr Holmes solves the mystery once and for all.
[Edit: Yeah, I believe you’re right about my own weakened immune system just waiting to be tipped over. Greg Jefferys wrote about a similar experience at the start of his HepC Blog…]
Cheers,
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).Gaj wrote:”When the moon is in the Seventh House
And Jupiter aligns with Mars
Then peace will guide the planets
And Wullie will squash the mozzies”Sorry, I was trying to think of something to equate the danger to and just couldn’t resist that opportunity.
“Once you eliminate the impossible, whatever remains, no matter how improbable, must be the truth.”
Arthur Conan DoyleOor Wullie goes off to play with his catapult and sharpen his pen-knife… (oops!)
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).Hi Gaj,
Agreed, there is good evidence the HVC does not replicate in the gut or saliva of a mosquito.
But here’s an article that says that mechanical transmission is at least possible for HCV (but not for HIV) on the grounds of the (pico-litre) volumes that would be necessary:
http://www.ncbi.nlm.nih.gov/pubmed/17521655
But what might happen if someone successfully manages to slap a mossie while it’s biting?
… the “mechanics” of which is best left to the imagination
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).Hi Beaches,
I have probably had HCV for about 39 years. After I was diagnosed, I contacted my ex-wife and other previous partners (not a big list) to tell them. Those that replied (not a big list) are all virus free.
I know I shared a mosquito a few times with my wife, but she was always the one who got bitten first and the most, so that doesn’t prove anything.
Funny thing is, a couple of years ago I got badly bitten by a mosquito one night in Rio, and about 10 weeks later I really started to go down-hill. 4 weeks later I was diagnosed with Hep-C. Probably the Brazilian mosquito was just a coincidence, but I still wonder about that…
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).Hi Gaj,
Sure, I understand all the arguments against mosquitos. But what about the “new” Zika virus? Seems to me like more of the same, and that it is malaria that is the exception (malaria is not a virus)….
Only Zika is more scary because if you catch it (and with a big “IF” here) you get sick very fast.
https://en.wikipedia.org/wiki/Zika_virus
As far as I can see, there is just too much of a pattern with all the other mosquito-borne flaviviruses (west nile, dengue, yellow fever, … and now zika) to make such an exception for HCV?
Well, that’s just my two cents…
Cheers,
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).CJ wrote:Is it really spread by sex? I always thought this wasn’t so?
& what about mozzies?
I know a lot say it isn’t, but I’ve always wondered?! as the mozzies seem to spread so many diseases.
xI know that medical opinion says that HCV is not transmitted by mosquitos like malaria is.
http://fixhepc.com/forum/media-news/936-baby-boomers.html#14888
But HCV has existed for long enough for it to have diverged into six (even seven) main genotypes and several subtypes (thanks for the nice graphic, Gaj). This means it is been in the human population for several thousand years at least, making it much more ancient than hypodermic syringes (both “medical” and “recreational”. So there must, surely, be some kind of “natural” transmission mechanism, even if HCV has not “evolved” like malaria has, right?
Suppose you have two people in the same room. One of them has HCV, and a mosquito bites them both during the same night. Setting aside the risk of malaria, probably nothing will happen except for some red bumps for breakfast, right?
Now repeat the experiment each night for 30 years. Sooner or later, wouldn’t there be a “shared needle” effect?
Well, its just a thought…
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).“If you’re riding ahead of the herd, take a look back every now and then to make sure it’s still there.”
— Will Rogers(nod to Mike)
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).mgalbrai wrote:All offending comments removed, I think..
Even Joy’s mugshot.
Keep me on topic folks!
mThanks a lot Mike … I was only kidding about “Apache Pass” (private joke)
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).The reason I post a lot on FixHepC is that I believe it is now THE reference site for legally accessing generic HCV treatment.
Our posts are being read by more and more people who are desperately looking for treatment.
But also they are being read more and more (I believe) by doctors, lawyers, regulators, activists, advocates, key decision makers, and maybe even politicians.
Me, I am hoping at the very least that the people in the French and UK Health Services are following what’s going on here.
Obviously its a political issue. But please, please, please can we keep gun laws and terrorists out of the argument?
Thank you for your understanding.
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).Price wrote:I can’t sign. US is not on the list.
Passing it to Brazil
Salut Price,
Vous ne connaissez pas que vous habitez aux Etats – Uni !?!?
Notre Guillaume
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).“Something is rotten in the State of Denmark”
William Shakespeare, Hamlet (1599 approx)
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).My English translation of the article in Le Figaro:
Médecins du Monde launches a shock campaign against the price of medicines
Key words: Médecins du Monde, Sovaldi, innovative drugs, generic drugs, pharmaceutical industry
By Thomas Delozier – 13/06/2016Médecins du Monde’s “The Price of Life” campaign starts today, despite being censured by advertising companies.
“In France, cancer earns 2.4 billion euros per year”… “an outbreak of flu in December gives a year-end bonus” … “with 1 billion euros in profit from hepatitis C, we’re doing very well.” … These shocking and cynical phrases are not lost to Médecines du Monde. In their latest poster campaign, “The Price of Life”, the NGO takes on the very high drug prices charged by the pharmaceutical industry and calls for a petition to be signed.
At stake are the exorbitant prices of drugs which lead to rationing, according to the NGO. Let’s take Sovaldi. Today, this innovative treatment against hepatitis C costs € 40,000 per patient. With about 230,000 people infected by this virus, treating every infected patient would cost more than 9 billion euros. “At these prices, the social security system cannot afford to cover the cost for everyone,” explains Olivier Maguet, who is in charge of the “Medicine Prices and the Health System” campaign, of which “The Price of Life” is a component. He adds “we find ourselves in the same situation as Mozambique or Zambia: we cannot treat people because we don’t have enough money. We have to make people aware of this crazy situation.”
However, don’t expect to see campaign posters for “The Price of Life” in all the metro stations or bus stops. They will be visible only through fly-posters, social networks, and the press. The three companies engaged by Médecins du Monde to advertise “The Price of Life” have refused to do it.
Media Transport justifies its decision in two ways: “there is a risk that the pharmaceutical industry could be negatively concerned by these posters”, and, “the reference to serious diseases could be perceived as offensive by people suffering from those diseases.” JCDecaux shares the second reason and adds “a lack of sources”. These two companies say they must follow the recommendations of the Professional Advertising Regulation Authority (ARPP), which delivers more than 15,000 recommendations annually to the media. The third company, Insert, could not be contacted.
Meanwhile, pharmaceutical companies are denouncing “a deceitful propaganda campaign” from Médecins du Monde and that its slogans “are not only damaging to industry, they are particularly shocking and disrespectful to the millions of people who fight daily against disease.”
Industry is not the main target of the campaign
“This is the first time Médecins du Monde has ever been censured,” said Olivier Maguet. “This clearly shows that we are pressing where it hurts. However, this is quite ironic because we do not mention any drug or laboratory names in the posters. We have nothing against the pharmaceutical industry, we need their medication, and we respect their profit motive. They are not our main target, it is the State! Because the State leaves them to it.”To alleviate the exorbitant price of Sovaldi, Marisol Touraine last month announced universal access to treatment, and not just critically ill patients. She also promised that the Economic Committee of Health Products (CEPS) was going to negotiate a lower price. Olivier Maguet’s response is that “we welcome the intention, but at the moment these are just promises. The CEPS remains quite opaque and allows little transparency. It’s a shame to follow that route, especially since there is another more radical way: the compulsory licence.”
The compulsory licence, permitted by article L613-615 of national law, allows the creation of a generic from a patented medicine if “it is made available to the public in insufficient quantity or quality or at abnormally high prices”. These conditions make Sovaldi eligible. A compulsory licence greatly reduces a drug’s price while providing royalties to the company that created the product so that it benefits financially.
Why has Marisol Touraine has not chosen this solution? “We asked her two years ago and she still has not replied yet,” regrets Olivier Maguet. “The only response we have is that she considers it to be a ‘weak legal instrument’. This is wrong!” Despite its low use – only a few times since the 1950s – the method is terribly effective. To refuse, a laboratory must engage in a legal battle which is very costly in terms of both money and image.
In 2001, 39 pharmaceutical companies filed a lawsuit against the Government of South Africa when it tried to promote the production of generic AIDS medications. The procedure stopped mid-way, and prices tumbled. “Unfortunately, this legal tool is not known to the general public,” says Olivier Maguet. “With this campaign, we want to go further than the simple status quo. We want to create a public discussion so that this situation might change.”
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).OK, I know its uncool to reply to my own post, but I have to put this cracking story from The Guardian (26 Jan 2016) somewhere:
Big Pharma’s Worst Nightmare
https://www.theguardian.com/society/2016/jan/26/big-pharmas-worst-nightmare
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3).Here is an English translation of the Médicines du Monde petition. Anyone from any country can sign up:
https://leprixdelavie.medecinsdumonde.org/fr/la-petition
Dear Minister of Health,
We are not teaching you anything by saying that the prices of medicines are constantly rising.
That such prices are absolutely unjustified.
That pharmaceutical companies are making outrageously colossal margins from treating the sick.
That the Social Security system is not able to pay for these treatments.
So we are teaching you nothing by saying that our Health System, and therefore our health, is in real danger.
So we would like to ask you a simple question:
When it comes to health, does the market make the law, or is it the State?
We therefore ask you to use all the legal and political means in your power to drastically lower the prices of innovative medicines.
Our health depends on it.
(194,232 signatures)
Diagnosed Jan 2015: GT3, A0+F0/F1. Fatigue + Brain-Fog.
Started Sof+Dac from fixHepC 10-Nov-2015. NO sides.
Pre-Tx: AST 82, ALT 133, Viral Load 1 900 000.
Week4: AST 47, ALT 58. VL < 15 (unquantifiable). Week12 (EOT): AST 30, ALT 26, VL UND Week16 (EOT+4): AST 32, ALT 28, GGT 24, VL UND Week28 (EOT+16): AST 26, ALT 22, GGT 24, VL UND Ever grateful to Dr James. Relapsed somewhere after all that... Bummer! Jan 2018: VL 63 000 (still GT3). -
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