Friday, 21 February 2020 12:41

Generic Maviret (glecaprevir/pibrentasvir) is coming

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There is some exciting news from the Medicines Patent Pool in that Mylan have signed on to produce a generic glecaprevir/pibrentasvir. https://medicinespatentpool.org/mpp-media-post/the-medicines-patent-pool-and-mylan-sign-agreement-to-scale-up-access-to-first-generic-version-of-hepatitis-c-treatment-glecaprevir-pibrentasvir/ This is really significant for areas of Africa where the subtypes of HCV are very resistant to DAAs, for patient…
Tuesday, 11 February 2020 22:10

WHO leading the way on the novel Coronavirus

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We live in a world of soundbites where complex issues are often condensed into memes and slogans. When it comes to fighting a global health threat like 2019-nCoV the simple reality is that memes and slogans are not going to cut it.…
Tuesday, 22 October 2019 12:16

Can we extend Hepatitis C cure to Hepatitis B?

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The new drugs that cure Hepatitis C are great but what people often forget is that they are our first-ever cure for a virus. It used to be thought that curing Hepatitis B was a pipedream but this breakthrough with Hep C…
The red ribbon used for HIV awareness has been a potent tool destigmatizing that disease. Several years ago conversations with Greg Jefferys about the Butterfly Effect and treatment advocates like Hazel Heal from New Zealand, Isabelle Andrieux-Meyer from Médecins Sans Frontières and…
Tuesday, 02 July 2019 22:34

Give us our PrEP!

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Hi All, We need your help. We don't normally do this but it's important. Ok, so what? In 2015 Swissmedic changed the rule that said a patient can import only 1 month of medication for their own use to say they could…
The development of Hepatitis C Direct-Acting Antiviral medications (DAAs), and their introduction to the market in 2013, was a major victory in the fight against the HCV virus. It was a breakthrough that rivalled the invention of penicillin because while penicillin was…
Friday, 17 May 2019 20:29

Epclusa® for Hepatitis C

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Epclusa (velpatasvir/sofosbuvir) for Hepatitis C Medically reviewed by Dena Westphalen, PharmD on December 20, 2018 — Written by Lindsay Slowiczek, PharmD   Reprinted with permission of Healthline. About Generic Side effects Cost Epclusa and alcohol Dosage Adherence Uses Alternatives Epclusa vs. Harvoni…
Thursday, 16 May 2019 21:05

Buy Generic Epclusa

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Released in 2016, Epclusa has the remarkable ability to cure 96% of Hepatitis C sufferers regardless of genotype. It was an exciting new drug from Gilead Sciences, the innovator of the breakthrough medication Harvoni. Unfortunately, similar to Harvoni, which was released two…
Wednesday, 13 February 2019 10:08

Confirmed: Hep C treatment saves lives

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So back in late 2017 the Cochrane Collaboration made the bold claim that treatment with Direct Acting Antivirals did not have any measurable impact on clinical outcomes. While the medical profession as a whole expressed a large and collective WTF sentiment new…
Wednesday, 06 February 2019 15:59

AASLD-EASL HCV Special Conference Miami 2019

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Jules Levin at NATAP has provided this awesome summary of the presentations from the combined AASLD/EASL HCV elimination conference. The first one starts with the elephant in the room, namely the prices... The Cost of HCV Elimination - AASLD-EASL HCV Special Conference…
When sofosbuvir first reached the market it was not approved for patients with CKD (Chronic Kidney Disease) stages 4 and 5 which means patients with an eGFR of < 30 ml/min. This was based on the observations that: Sofosbuvir is rapidly metabolised…
Friday, 18 January 2019 14:57

Sound Therapy for Tinnitus

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Perhaps it's age, perhaps it's Hep C, perhaps it's the medication. Whatever the reason, the reality is quite a few people with Hep C have issues with tinnitus. A friend of mine called Davo had this issue and resorted to Google where…
Saturday, 05 January 2019 16:54

Maviret (Mavyret) is an awesome drug for HCV

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It's come to my attention that some people on the Internet are "bad-mouthing" Maviret (Mavyret) and suggesting it's the worst option on the market and that you need Sofosbuvir. Anyone stating this does not, as they say, know their ass from their…
Thursday, 27 December 2018 12:49

83 Hepatitis C Studies From AASLD 2018

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For the past 2 decades, Jules Levin at NATAP has done a fantastic job reporting what is presented at all the major scientific meetings on HIV, HBV and HCV around the world. Here are 83 studies presented at the AASLD 2018 conference that cover…
Monday, 17 December 2018 14:07

PHARMAC announces funded Maviret from Feb 1st 2019

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In an announcement worthy of 3 dancing bananas , PHARMAC in New Zealand have just announced: We are pleased to announce a decision to fund a new treatment for chronic hepatitis C infection, glecaprevir and pibrentasvir (Maviret) from 1 February 2019, and to…
Here is a summary slide set where expert faculty members summarize key viral hepatitis studies from AASLD 2018 in San Francisco. Use these slides to review data on newer HCV regimens, the HCV continuum of care, posttreatment HCV outcomes, HCV D+R- transplantation,…
The usual way we detect Hepatitis C is using an Antibody test. Following infection with Hepatitis C the body forms antibodies to the virus and these antibodies persist lifelong. In about 25% of patients the antibodies successfully remove the virus, however, the…
Tuesday, 13 November 2018 08:38

Generic Mavyret (Maviret) Coming Soon!

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The Medicines Patent Pool Signs Licence with AbbVie to Expand Access to Key Hepatitis C Treatment, Glecaprevir/Pibrentasvir SAN FRANCISCO, November 12, 2018 /PRNewswire/ -- Important collaboration will ensure affordable hepatitis C treatment options in low- and middle-income countries.   The Medicines Patent Pool (MPP) has today announced…
Thursday, 08 November 2018 17:09

Liver Cancer (HCC) Treatment Options

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One of the feared complications of Hepatitis C is HepatoCellular Carcinoma (HCC) aka Liver Cancer. While anyone can get this type of cancer it is most common in patients who have liver cirrhosis from any cause. We look for it using a…
Thursday, 08 November 2018 09:44

Hep C Guidelines - An Executive Summary

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Detailed expert guidelines are great but often run to hundreds of pages meaning it can be hard to find the specific information you want. Giten Khwairakpam from TREAT Asia / amfAR just shared this awesome executive summary with me, so I'm sharing…
Saturday, 27 October 2018 11:48

So you're cured of Hepatitis C - What next?

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So you've made it! SVR12 and you are cured of Hep C. Maybe you battled your insurance company for access to the medications. Maybe you sourced generic medications yourself. For most patients at this point that's it. It's over. You're cured and…
Here is an article from the South Centre in Geneva. Abstract: In late 2013, a new Hepatitis C treatment called direct-acting antivirals (DAAs) was introduced in the market at unaffordable prices. The eradication of the disease is possible if medicines can be purchased…
Friday, 12 October 2018 00:10

Understanding AFP (Alpha Feto Protein)

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AFP is short for Alpha FetoProtein. As the "feto" in the name suggests this is a protein we see in a fetus. In adults we switch off the genes that produce it so we don't see much (usually <12 units) Hepatocellular Carcinoma (HCC) represents…
Thursday, 11 October 2018 12:34

Are The New Hepatitis C Treatments Poisonous?

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So today, on the chat a patient mentioned "My doctor here is scaring me from getting treated. He is tell that the treatment can be poisonous." 5 years ago this doctor would have been correct, in fact, I used to think the…

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