Home Forums Main Forum Experts Corner Fibrosis and Cirrhosis Long term risks for ex-Hep C patients???

Viewing 9 posts - 1 through 9 (of 9 total)
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  • #27977
    GillA
    • Topics: 2
    • Replies: 2
    • Total: 4
    • Novice
    @gilla

    Hi Everyone – I took the Harvoni treatment in 2016 and have been clear of Hep C since August of that year. All my blood results, ultra sound scans and fibroscan results are completely normal – Great news you would think. However my consultant is insistent that I am still at HIGH risk of developing cirrhosis, tumours, etc and that despite my excellent health now, I still need to do 6 monthly bloods and scans. I refused an endoscopy to look for varices in the gullet.
    Talk about taking the shine off feeling well! I would like to know if anyone has experience of this gloomy opinion. I don’t believe that continuing to carve my life into 6 monthly pieces with all the stress that creates, is in the long term healthy.

    #27978
    beahavan
    • Topics: 5
    • Replies: 81
    • Total: 86
    • Guardian Angel
    • ★★★★★
    @beahavan

    I finished Harvoni treatment in November 2016. My doctor told me that I would be at elevated risk for liver cancer for 10 years. He is going to want to do a liver ultra sound next year.


    G4
    F0-F1
    diagnosed in 2006
    Tx naive
    Treatment started 8/12/16, Ledipasvir/ Sofosbuvir (Harvoni) supplied by Monkmed
    8/1/16 ALT 36 AST 40
    1/4/17 ALT 17 AST 21
    7/13/17 ALT 17 AST 25
    12/28/17 ALT 22 AST26
    2/22/18 ALT 19 AST 25
    7/10/18 ALT 26 AST 32
    1/8/19 ALT 16 AST 28
    7/2/19 ALT 16 AST 26
    Hcv Rna, Quantitative Real Time Pcr <15 NOT DETECTED (IU/mL) NOT DETECTED

    #27979
    Avatar photorohcvfighter
    • Guardian Angel
    • ★★★★★
    @rohcvfighter

    Hi GillA,

    I guess it depends on what drives you to get checked.
    In my case, I prefer to do the 6 months check just to know that I am doing fine. In case something would not be fine, I would have a higher chance to fix the health issue by starting earlier to treat it, before things get worse.

    Cheers,
    RHF


    In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
    HCV kills more than 500000 people every year. HCV generic drugs work. Don’t become a statistic.
    By sharing this Youtube video you might save someone’s life!
    My TX: HEPCVIR-L[generic Harvoni]-India
    SVR52 achieved

    #27981
    beahavan
    • Topics: 5
    • Replies: 81
    • Total: 86
    • Guardian Angel
    • ★★★★★
    @beahavan

    I get blood work every 6 months. It’s been 3 years since my last liver ultra sound.


    G4
    F0-F1
    diagnosed in 2006
    Tx naive
    Treatment started 8/12/16, Ledipasvir/ Sofosbuvir (Harvoni) supplied by Monkmed
    8/1/16 ALT 36 AST 40
    1/4/17 ALT 17 AST 21
    7/13/17 ALT 17 AST 25
    12/28/17 ALT 22 AST26
    2/22/18 ALT 19 AST 25
    7/10/18 ALT 26 AST 32
    1/8/19 ALT 16 AST 28
    7/2/19 ALT 16 AST 26
    Hcv Rna, Quantitative Real Time Pcr <15 NOT DETECTED (IU/mL) NOT DETECTED

    #27982
    Avatar photoHazel
    • Guardian Angel
    • ★★★★★
    @hazel

    Hi GillA
    Despite my previously decompensating, cirrhosis being all resolved, and my liver looking as good as anyone else’s pretty much now, my specialist says- “will need 6 monthly scans for life to monitor risk of HCC”. I have one next week, but I must say , I still like getting them because it is so good to see, where I came from to now. I suppose I will get sick of it sometime, and I don’t think, myself, my risk is high at all. But, I’m grateful to get the scan and monitoring, when I see how hard it is for lots of people around the world to get the help they need. My local hospital has lots of issues, but in this, I am well served.


    Genotype 3 30 years, 2x treatment interferon/ribavirin non responder. Cirrhosis 17 years. Fibroscan, decompensating, 40 down to 22 by 29/3/16- now down to 6.5, normal, no cirrhosis. Started Buyers Club Sof/Dac 14 Nov 15. SVR 12 29/0716

    #27987
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hello GillA,

    If you had cirrhosis prior to treatment then you are at increased risk of developing HCC and an Ultrasound every 6 months works well to keep an eye on it.

    At SVR your liver gets better not worse, so cirrhotics become less cirrhotic or even fibrotic. All cause mortality is substantially reduced at SVR so there is less liver failure, less HCC and less everything else that falls into the extrahepatic manifestations.

    clinical-events-related-to-hepatitis-c-treatment-response.jpg

    As you can see from this graph you are about 1/3 as likely to die, 1/5 as likely to get HCC and 1/10 as likely to progress to liver failure. All good reasons not to paint a gloomy picture!

    If you did not have cirrhosis prior to treatment your specialist is just being extra cautious.


    YMMV

    #27998
    GillA
    • Topics: 2
    • Replies: 2
    • Total: 4
    • Novice
    @gilla

    Thank you so much – at last some straightforward information for me to think about. I really do appreciate your response.

    #28031
    Avatar photoSven
    • Guardian Angel
    • ★★★★★
    @sven

    1E9D6BCE-5B33-435B-8AF8-10A939B3D9B3.jpeg

    Here is my 1.5 year bloods and cancer screen, all incredible.
    My liver and blood tests have never looked better in 30 years. My GI doc wants an ultra sound and I agreed. He states my results will help the next patient but I have ultra low risk in getting any HCC or cirrossis due to the successful DAA treatment completed.
    I paint a sunny picture, I won’t and don’t live in health fear.


    Contracted HCV 1980’s
    Geno Type 1a
    F3 ( doc says once treated I’ll be F2 maybe F1)
    Meds shipped 6/17/2016 arrived early 7/2016

    Viral count – 3,471,080

    4 week quantitative bloods: August 17, 2016. I have been diagnosed as <15 (told undetected)

    8 week quantitative bloods: September 14th. I have been diagnosed as <15 (told undetected)

    11 week PCR RNA Qualitative bloods: September 26th 2016 – Undetected

    December 19th 2016: Cured!
    Viral count: zero!!!
    2018 viral count: still zero!
    Cured!

    #28032
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Those are some great looking numbers Sven!

    #dance


    YMMV

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