Don't take this the wrong way but......sometimes when I read this forum I think people could be forgiven for thinking the DAAs cause certain individuals to LOSE THEIR FUCKING MINDS!
I'll come to that in a moment. First to the question of using DAAs prophylactically. I asked this some months back
. You can read the doc's response for yourself.
Now as to Professor Gane. The doc commented on that
. Please read it again. Here are some more of James'
about the Prof. I think some of you may have misinterpreted his response. Prof Gane, as far as we know, is not the enemy, is not being disingenuous, is not trying to scare the bejeezus out of everybody.
In the words of Tom Robbins, the enemy is dullness of mind.
This is like the whole Seymour thing all over again. And look at how well that ended.
Lost ourselves one good source of information there.
My guess is no one's tested to see if the Mesochem drugs are bioequivalent because that level of reverse engineering may not be possible. And in a post that I can't find from the doc, IIRC he said it may not even matter if they are not exactly bioequivalent.
Bottom line, the Mesochem APIs might not work (my understanding is Incepta are just combining them to make Twinvir). In the same post I can't find right now the doc points out there are good reasons to believe it will all be ok. Moreover, Mesochem is a big company and have a considerable reputation at stake. It would not be in their interests for this whole thing to go belly up.
Nevertheless, the drugs might not work. They might not work because they are not bioequivalent to the proprietary medications. They might not work because sometimes even the proprietary drugs don't work. Here's something to worry some more about if you feel you must. These drugs have been fast tracked. Nobody knows for sure yet what the long term effects may be.
As John Lennon said, "life's what happens when you're busy making other plans."
Worrying is just gonna make you sick not better. And that's dumb because there's sweet FA that any of us can do about the situation beyond what we've already done.
Look good people, in all likelihood, you're going to be cured. Really you are. But maybe you won't be. You won't know until you know. But please don't waste your time fretting over something that hasn't happened yet and that you can't change even if it does. As far as relapsing goes, what I've been told is that if you hit it again harder, you almost certainly get it the second time around. So the odds of not being cured keep getting smaller. What's more, if you said to me 10 years ago that within a decade we'd have drugs that would cure most cases of HCV, I'd of laughed in your face.
But here we are.
Likewise, as has already been pointed out, better and better drugs are on the horizon. But nothing in life is certain. Ever. In the meantime, all you can do is.........
Oh and in regard to this....
Blimey. Enkel, I know the man in question he was Geno type 4 Pre treatment
and post treatment he was Geno Type 3 his consultant same as mine explained it too me.
Geno type mutation is not unheard of!
I could be wrong, but I think it is unheard of. Mutations of genotype into a more resistant strain of the same genotype, yes. Mutation of one geno into another, I don't think so. My bet would be this person has gotten reinfected with a different genotype.