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TOPIC: Re-treating with Vosevi
Re-treating with Vosevi 4 years 2 months ago #25931
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |
Re-treating with Vosevi 4 years 2 months ago #25933
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YMMV |
Re-treating with Vosevi 4 years 2 months ago #25940
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |
Re-treating with Vosevi 4 years 2 months ago #25946
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Gen 1a Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 |
Re-treating with Vosevi 4 years 2 months ago #25947
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G1a dx'd in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn't last long it felt horribly ugly!! I stopped tx, after 5 weeks!! Started tx 6/1/16 with Harvoni. 12 Month Labs= UND |
Re-treating with Vosevi 4 years 2 months ago #25954
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |
Re-treating with Vosevi 4 years 2 months ago #25991
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G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!) Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back! New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217. SVR12 and SVR 24... |
Re-treating with Vosevi 4 years 2 months ago #25997
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |
Re-treating with Vosevi 4 years 1 month ago #26082
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |
Re-treating with Vosevi 4 years 1 month ago #26085
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YMMV |
Re-treating with Vosevi 4 years 1 month ago #26090
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Gen 1a Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 |
Re-treating with Vosevi 4 years 1 month ago #26094
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |
Re-treating with Vosevi 4 years 1 month ago #26095
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |
Re-treating with Vosevi 4 years 1 month ago #26097
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G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!) Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back! New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217. SVR12 and SVR 24... |
Re-treating with Vosevi 4 years 1 month ago #26232
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Diagnosed: 2001 GT1a , HCV since mid-70's. Biopsy 2010 F1 Fibroscan and Fibrosure 2018 F2 Treated in trial 2010 with Dac/Peg/ Riba and Relapsed. Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac. Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U) VL start: 1.6mill.ALT 125 AST 88 Wk. 4 Det @LLOQ <15. VL Wk.8 UND Alt &Ast 22 Wk. 12 UND EOT:UND EOT+12 >>>UND (SVR12)! ALT11 AST13 Nov6/18 SVR 24! |