Home Forums Main Forum Patient Stories F3 to F1 in 12 years while still HCV positive?

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  • #9350
    Avatar photoSirchinenge
    • Guardian Angel
    • ★★★★★
    @sirchinenge

    Drinking is the killer in all this drugs don’t do much if any damage to your liver the shit
    dope is cut with causes other problems.

    Am not sure you’re right about progression I know some people who progressed very quickly in less then
    a few years whilst living a clean life.


    Sob/Dac from Oct 29 2015
    Geno 1b
    Fiberscan 9.9 Pre treatment
    Fiberscan 7.4 week 10
    VL 1.3 million pre treatment
    Week 2.5 VL 96
    Week 5.5 VL 17
    Week 10 VL UD
    SVR 3 UD
    SVR 16 UD
    Cured:
    All liver functions in normal ranges.

    #9352
    Tommy
    • Guardian Angel
    • ★★★★★
    @tommy

    I agree with everything you wrote. When it comes to progression each person is different. The ten years was taking from a few websites produced various studies. It is just a “about” number the professionals came up with I would think from the studies.


    Genotype 1A
    ALT 473
    AST 226
    Virus Load 3,119,030
    Results as of May-2016
    5 week viral load/undetected as of 12/02/2016
    Liver Biopsy Results from Feb 2013
    Portal/Periportal chronic inflammation and mild interface hepatitis (Grade 2)
    Focal Lobular chronic inflammation (Grade 1)
    Portal/Periportal fibrosis (stage 1-2 trichrome and reticulin stains utilized)
    Negative Iron stains.

    #9359
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Bloot, you are cheating by treating!

    Fibrosis does improve post treatment:

    http://fixhepc.com/forum/experts-corner/106-liver-cirrhosis-does-not-disappear-in-12-weeks.html

    The fibrosis seems to be mediated by LOXL2

    http://fixhepc.com/forum/media-news/338-good-news-for-cirrhotic-patients.html


    YMMV

    #9361
    Avatar photoSirchinenge
    • Guardian Angel
    • ★★★★★
    @sirchinenge

    My fiber scan was 9.9 before treatment at week 10 of treatment my fiber scan was 7.4.

    Who knows I certainly don’t!


    Sob/Dac from Oct 29 2015
    Geno 1b
    Fiberscan 9.9 Pre treatment
    Fiberscan 7.4 week 10
    VL 1.3 million pre treatment
    Week 2.5 VL 96
    Week 5.5 VL 17
    Week 10 VL UD
    SVR 3 UD
    SVR 16 UD
    Cured:
    All liver functions in normal ranges.

    #9366
    Avatar photoBloot
    • Topics: 3
    • Replies: 65
    • Total: 68
    • Recovery Champion
    • ★★★★
    @bloot

    Thanks for the good feedback everybody
    i guess the message is be pleased with my results but don’t take them as difinitive

    I can confidently say though that my liver is not chirrotic which was my primary concern (my blood count has always been good)
    I’m lucky I kicked the death wish with enough time to recover from much of the damage done

    It’s been an odd process this treatment as it constantly leads me to think a lot about life and death and choices made
    The nurse at Nepean said that being a previous F3 it’s likely I will need yearly cancer screening
    If I get cancer I will not partake in sickness prolonging procedures and so reasearched getting some Nembutal as an insurance policy
    As an F1 she says the testing is not necessary and the Nembutal can remain in the back of my mind hopefully forever

    I’m almost half way through the 24 weeks and while the physical symptoms are minor I will be glad when it’s over for the emotional toll
    While I’m on the tx I find it hard to just get on with life as before because of the regular hospital visits and discussions about it
    I might even get an appt with Dr F and see if there are any negatives to continuing tx for 24 weeks given my fibro and blood test results

    Anyhoo, I’m rabbiting again and it’s the weekend
    It helps (I think) to write this stuff down and get it out of my head so thanks to this forum as it’s the only place I can

    Cheers


    52 y.o. G3a for about 30 years
    Previous tx 2004 interferon/ ribavarin
    2004: ALT 624 AST 263

    Pre tx test 23/10/15: ALT 153 AST 128 VL 11 849 493
    6/11/15: Sof/ dac started
    26/11/15: ALT 41 AST 41
    7/12/15: ALT 36 AST 30 Virus undetected

    2004 biopsy F3
    Fibroscan appt Jan 11 2016.

    #9370
    Avatar photoBloot
    • Topics: 3
    • Replies: 65
    • Total: 68
    • Recovery Champion
    • ★★★★
    @bloot
    ”James-Freeman-facebook” wrote:

    Bloot, you are cheating by treating!

    Fibrosis does improve post treatment:

    http://fixhepc.com/forum/experts-corner/106-liver-cirrhosis-does-not-disappear-in-12-weeks.html

    The fibrosis seems to be mediated by LOXL2

    http://fixhepc.com/forum/media-news/338-good-news-for-cirrhotic-patients.html

    That’s interesting
    I was tested at week 9-10 as it was the earliest I could get one done
    It seems likely that the no virus detected at week 4 could be part of the story of the reduction in F score


    52 y.o. G3a for about 30 years
    Previous tx 2004 interferon/ ribavarin
    2004: ALT 624 AST 263

    Pre tx test 23/10/15: ALT 153 AST 128 VL 11 849 493
    6/11/15: Sof/ dac started
    26/11/15: ALT 41 AST 41
    7/12/15: ALT 36 AST 30 Virus undetected

    2004 biopsy F3
    Fibroscan appt Jan 11 2016.

    #9371
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj
    Bloot wrote:

    Anyhoo, I’m rabbiting again and it’s the weekend

    :woohoo: Luverly, haven’t been rabbiting in years. Send me a brace, I like a good stew! B)

    …..and thank you for posting, it helps take our minds off what I’m sure are similar feelings and emotions for many of us as well. :)


    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    #9522
    Avatar photosabrecat
    • Guardian Angel
    • ★★★★★
    @sabrecat

    Hi Bloot,

    I had my biopsy done in 1998 – it took five passes and before the chap trying to do it was done the theatre had filled with men who looked somewhat senior and concerned. Had to stay overnight and not allowed out of bed for some hours.

    Could not have a fibroscan done due to the person doing it being convinced he could not do it. Anyway, I had a liver resection in 2012 – nearly as good as an autopsy for the purposes of measuring scaring I should think, and was F3. Pretty confident I may be F4 now, hence the 24 weeks Sof/Dac.

    My rationale with respect to all this? Even with half the liver missing, I figure not having HCV will help things not get worse; if it helps the scaring get better then it’s a bonus.

    Yours

    J.

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