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  • 24 November 2015 at 7:03 am #4547
    Avatar photo2b
    • Guardian Angel
    • ★★★★★
    @2b

    Don’t know if this is new news or not, but it was dated today in this article,

    http://www.bloomberg.com/news/articles/2015-11-23/bristol-myers-lets-low-income-countries-copy-hepatitis-c-pills

    GT 2b; since 80’s, no prior tx, sofosbuvir and daclatasvir compounded from API’s at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. I feel GOOD!! I knew that I WOULD!””

    24 November 2015 at 7:17 am #4550
    Avatar photocoral
    • Guardian Angel
    • ★★★★★
    @coral

    Hi 2b,

    At face value it looks as if Bristol-Myer are trying to take a more reasonable, broad and humane approach to the treatment of Hep C. I imagine there must be some hurdles to jump to do any collaborating with Gillead. Good to see the increasing media focus on Hep C and the broader distribution.

    Coral

    24 November 2015 at 8:24 am #4553
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj

    Yes, looks like it is news, and good at that.

    This will allow manufacture of a combination Sofosbuvir/Daclatasvir single pill similar to Harvoni or Twinvir (Sofobuvir/Ledipasvir) which hasn’t been available till now. So single pill treatments available to cover all genotypes soon now I believe.

    Only for developing countries but will simplify treatment in those areas and presumably cheaper as Dac is much less expensive than Led.

    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    24 November 2015 at 10:48 am #4558
    Avatar photodarbara
    • Guardian Angel
    • ★★★★★
    @darbara

    Yes this is news.

    Treatment naive
    F 3/4
    Genotype 1 a & b
    V/L 17 MILLION
    Started Harvoni 11th Dec 2015 for 12 weeks
    4 weeks VL UND
    6 WEEKS ALT 32, AST 34
    EOT 03/03 2016 ! UND
    ALT 34, AST 26
    04.04.2016 SVR 4
    26.05.2016 SVR 12
    16.08.2016 SVR 24

    24 November 2015 at 1:13 pm #4561
    Avatar photoLondonGirl
    • Guardian Angel
    • ★★★★★
    @londongirl

    Hi 2b, Yes just read this on Twitter, has to be a positive :)

    GT1a Dec14 F2/8.7 VL 900000-2.5M
    Jan16 Hepcivir-L MonkMed/Redemption
    Baseline: VL 913575 Alt 76 Platelets low
    Wk2 VL1157 Alt 23
    DET Wk 8 VL 32 Alt19 ‘In the slow lane’
    June16 Fibro 5.7 F0/1 LIF 1.5
    Wk 11 VL<12 Alt 13 Det/Unq
    Extending tx 12 wks Mylan Sofo/Dac MonkMed
    Wk 14 VL <12 Det/Unq
    Wk 16 VL UNDETECTED
    Wk 22 + 4 Wks Sunprevir FixHepC
    Wk 24 UNDETECTED Alt 13
    Wk 12 post tx SVR12 Wk 26 SVR24
    Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

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