Generics Late Breaker Accepted for EASL in April

This topic has 43 replies, 21 voices, and was last updated 8 years, 8 months ago by jimmy42.

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12 April 2016 at 2:30 am #15249
pat1
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- Guardian Angel
@pat1
wonderful news on your SVR12 Joy
awesome

gt 1a VL 6m
F2/3 FibroScan – 9KPa in 2011 and 7KPa in 2015
sof/dac 10 December for 12 weeks
pre tx alt 85 ast 51
4 wk alt 34 ast 31 UND <35
8 wk alt 29 ast 32 UND <15
12wk alt 25 ast 25 EOT 3.3.16
SVR24 UND KPa5.3 F0 in normal range
I am well
.forever grateful to fixhepc
12 April 2016 at 5:33 am #15268
Tina-Hill-facebook
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- Guardian Angel
@tina-hill-facebook
Great news Joy!

SVR 24
12 April 2016 at 8:45 am #15292
Ariel
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@ariel
I LOVE that I logged in and found all this happiness…Massive congratulations to you Joy for SVR12, and to Pat and Jaz for SVR4…what a wonderful read. The site is beginning to have more and more of these fantastic results coming through I love being in this good company. Yay! Onwards and no more HepC
12 April 2016 at 8:06 pm #15341
mgalbrai
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@mgalbrai
The “Flip Book” of conference abstracts:

http://ilc-congress.eu/wp-content/uploads/2016/abstracts/flipbook/mobile/index.html#p=1

Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
13 April 2016 at 1:10 am #15355
LondonGirl
- Topics: 16
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@londongirl
Wow- The amount of work that must be involved -in all this – Pretty awesome !

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 ‘In the slow lane’
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
13 April 2016 at 2:29 am #15362
Tina-Hill-facebook
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@tina-hill-facebook
I agree LG

The presentation is going to be EPIC! Im hoping there will be some well versed “Flipping of the Bird” dished out to all those doubters.

SVR 24
13 April 2016 at 2:43 am #15363
Ariel
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- Guardian Angel
@ariel
I was happy and honoured to be asked by Hieu to send my path for James, Thank you James for representing us all. Safe travels and keep breaking ground and bread with the usual suspects on our behalf, I appreciate it so much.
Ariel the thankful mermaid.
Mike ty for the link for the flipbook, I have read a fair bit since I woke at 4.30 am haha. Over a week since EOT…sleep patterns slowly resuming. Slowly…..
14 April 2016 at 12:21 am #15428
Hazel
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@hazel
The EASL excitement is building….. will be Sunday NZ time I calculate. There is a torrent of UND’s and SVR’s coming in. I noticed in the flip book Mike posted that a Prof Gane paper is first up on the page of late breakers on the 16th. I think relates to tx naive G3’s.

There will be so much useful info coming out of this conference. But I love that Dr Freeman is presenting results that includes everyone, F0-4, all genotypes- this is really what we, and medical profession, need to know now.

Genotype 3 30 years, 2x treatment interferon/ribavirin non responder. Cirrhosis 17 years. Fibroscan, decompensating, 40 down to 22 by 29/3/16- now down to 6.5, normal, no cirrhosis. Started Buyers Club Sof/Dac 14 Nov 15. SVR 12 29/0716
14 April 2016 at 4:10 am #15433
Archer
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- Recovery Champion
@archer
I started uploading bloods on my GP2U records for Dr James sometime ago – intending to later add later SVR results – if I am fortunate enough for them to eventuate. However I realised that the results being sought and confirmed by Dr James are for purposes of establishing a multi variate profile of final outcomes with the “generics”. Throughout my treatment, and perhaps others, I have used inconsistent regimes of generics from India and Mesochem, but also Daclatasvir provided compassionate grounds and Sofosbuvir from Gilead. It would be impossible I imagine to extrapolate differences or correlations attributable to any particular medication along with other variables (ie genotype, prior tx, cirrhosis etc) – so I realised my data will not add value so I have ceased recording. However, It seems that the numbers of members coming through fully generic treatments is steadily increasing and the data will be interesting for everyone – in its ramifications, both medically but also politically
14 April 2016 at 5:53 am #15444
mgalbrai
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- Guardian Angel
@mgalbrai
The name is Freeman.
James Freeman.
Attachments:
Curehcvnow@gmail.com
http://forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
14 April 2016 at 6:52 am #15450
fretboard
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- Guardian Angel
@fretboard
I’ll bet you anything that a video is gonna be made of this generic rebels presentation for all of us to see, that’s my hope anyways.

G1a dx’d in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn’t last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND
14 April 2016 at 8:12 am #15454
emilio
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@emilio
Good luck with the presentation James yours will be the jewell in the crown . Cant wait to see the footsge. Anyone know final cohort numbers? Em
16 April 2016 at 7:32 am #15554
fretboard
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@fretboard
I hope the Generic Rebels presentation goes well!! I know it will, how could it go wrong with the likes of our favorite Doctor and all the Rebels in Redemption!? Maybe the next stop will be at the Liver Meeting in the US in November. Wouldn’t that be something, Gilead would poo poo their pants.

http://www.aasld.org/events-professional-development/liver-meeting%C2%AE-2016

G1a dx’d in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn’t last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND
16 April 2016 at 11:23 am #15566
jimmy42
- Topics: 2
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- Acolyte
@jimmy42
hm, my data is in there somewhere, last bloods good at svr4 now 8, went through all this years ago with my brother on peg/riba, used to pick him up from the clinic with his doses in a cold pack so they wouldnt spoil, allergic to interferon I couldnt take the same route,
now 8 weeks eot I have some of my brain back(I was very ill with hcv mental symptoms) I am back doing IT stuff after a 6 year break working in a factory, just got a new job back in IT, working on panels again, updating systems etc, extra 10k plus car phone etc, long road,, but worth the hike,
cant wait to see docs presentation, Im a difficult patient, but he persisted,
such a big change from how I used to feel,, I smile again, laugh at silly stuff, and no more “Mr Cranky Pants”
So good to become part of the solution after being the problem for so long,
hugs all
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