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  • 14 September 2018 at 5:40 am #28545
    Avatar photobeaches
    • Guardian Angel
    • ★★★★★
    @beaches

    Hi everyone
    I have a colleague whose mother lives in Delhi, India and has HCV. It seems her doctors don’t know much about generics and from what my colleague says there is some distrust of the Indian labs among Indians.
    Can I please get some advice so my colleague can help her mother become HCV free?
    Her viral load is quite high but it seems her liver functions don’t get tested and I don’t believe she has ever had a fibroscan.

    Genotype 1a
    Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
    Harvoni treatment, started 19 March 2016
    4 week results Bilirubin 12 down from 14 pre treatment,
    Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
    VL <15 down from a lazy 6 million or so

    EOT Results
    Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

    12 Weeks post EOT
    Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
    Cured baby

    14 September 2018 at 11:13 am #28546
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hello beaches,

    Please get her to email me james@fixhepc.com and we can help arrange things for her.

    In a perfect world we do all this: https://fixhepc.com/what-your-doctor-needs.html

    If you are seeing a doctor about getting a prescription you can save yourself time, money and hassle if you bring all the things that are required.

    Your doctor will need to know:

    Genotype (1 to 6 with or without a and b)
    Fibrosis by scan or biopsy (either as F score or kPa) or by APRI (from blood tests CBC and LFT)
    Hepatitis B status
    Prior Treatments – what and when
    Current Medications

    While you doctor can look these up (provided you know where they were done) it saves a lot of time if you have copies but if you don’t have copies, don’t worry.

    Each of these impacts on the best choice of medications and duration.

    Daclatasvir interacts with some common medications.

    Routine tests pre-treatment

    Full Blood Count
    Liver Function
    Creatinine
    Electrolytes Urea
    Viral Load
    Hep C surface Antibody, Hep C core Antibody +/- Hep B surface Antigen (for core positive, surface negative chronic Hep B patients)
    AFP (Alpha Feto Protein) – a screen for hepatocellular carcinoma

    YMMV

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