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  • 26 February 2016 at 12:16 pm #12733
    dope-on-a-rope.jpgDr James
    • Guardian Angel
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    @fixhepc

    With the Sof it will go

    1/2 1/4 1/8 1/16 1/32 1/64 1/128 every day so under 1% after 1 week.

    With the led your 10% left is pretty close to the mark.

    And with the Riba it will take a while but people seem to feel better earlier than the numbers suggest.

    Some people suffer on Sof and sail through Riba so it depends what the cause is. I expect you will feel better every day and the trend will speak to how long.

    YMMV

    27 February 2016 at 12:58 pm #12815
    A.L.
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    • Recovery Champion
    • ★★★★
    @a-l

    Thanks for the information.

    Of course you are right that eventually all will return to normal, but it is odd that there is such variance among people for what seems to be a fairly potent drug such as ribavirin.

    But I guess that is the nature of genetic and physical variation between people.

    In the end, I don’t expect to feel a huge improvement after treatment as I think that being on the distal side of fifty and losing energy pretty much go hand-in-hand. The main bonus I am hoping for is a a bit more vitality, a slightly slower decline, and some delay of unpleasantnesses such as cirrhosis.

    Death and sickness is going to get us in the end, but with a healthier body, the path there will be a little less onerous. And that is certainly worth a lot in itself!

    G4, F4, cirrhosis.

    Thank you to Gilead, Michael Sofia, and the terrific folk at FixHepC for making this adventure possible.

    YEAR….. ALT….. AST….. GGT… FERRITIN………………………………….
    2009……. 210….. 215….. 953….. 1400……….. (Bad health, stupidity)
    2015……. 60……. 45……. 150….. 360…………. (Improved diet and health, FixHepC treatment)
    2016……. 20……. 24……. 25……. 156…………. (SVR 12)

    27 February 2016 at 3:07 pm #12826
    Avatar photodointime
    • Guardian Angel
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    @dointime

    Hi A.L.

    I stopped the riba after 12 weeks but continued on with the DAA’s. Here’s my experience.
    During the riba my haemo dropped from about 14 to 11.5.

    After stopping, I started to feel a difference after 2 weeks, by which time the riba had reduced to 50%.
    It was easier going with walking, less heart beating, easier breathing.

    After 4 weeks my haemo was up again to 13, nearly normal. Breathing normal, heartbeats normal. Riba reduced to about 25%.
    So I’d say to test your haemo at 4 weeks post and look for significant improvement based on that result.

    As I’m still on the DAA’s I still feel fatigue effects from them, so what I’m reporting here is due to stopping the riba only, not stopping all the meds.

    dt

    27 February 2016 at 5:54 pm #12846
    A.L.
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    • Total: 64
    • Recovery Champion
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    @a-l
    dointime wrote:

    Hi A.L.

    I stopped the riba after 12 weeks but continued on with the DAA’s. Here’s my experience.
    During the riba my haemo dropped from about 14 to 11.5.

    After stopping, I started to feel a difference after 2 weeks, by which time the riba had reduced to 50%.
    It was easier going with walking, less heart beating, easier breathing.

    After 4 weeks my haemo was up again to 13, nearly normal. Breathing normal, heartbeats normal. Riba reduced to about 25%.
    So I’d say to test your haemo at 4 weeks post and look for significant improvement based on that result.

    As I’m still on the DAA’s I still feel fatigue effects from them, so what I’m reporting here is due to stopping the riba only, not stopping all the meds.

    dt

    Thanks, dt, that is very heartening to hear! I’m more-or-less in the same haemoglobin park as you and finding the weakness and breathlessness far more unpleasant than the main condition itself, so it’s good to hear that you found yourself on an upward trajectory and that your figures correlate with what we have read about the half life of ribavirin.

    Just a matter of patience, I guess.

    In any case, good luck with the ongoing side effects of the antivirals and best wishes for a healthy conclusion.

    G4, F4, cirrhosis.

    Thank you to Gilead, Michael Sofia, and the terrific folk at FixHepC for making this adventure possible.

    YEAR….. ALT….. AST….. GGT… FERRITIN………………………………….
    2009……. 210….. 215….. 953….. 1400……….. (Bad health, stupidity)
    2015……. 60……. 45……. 150….. 360…………. (Improved diet and health, FixHepC treatment)
    2016……. 20……. 24……. 25……. 156…………. (SVR 12)

    27 February 2016 at 6:09 pm #12848
    Avatar photodointime
    • Guardian Angel
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    @dointime

    Hi A.L,

    Just a matter of patience, I guess.

    I agree. Don’t push it. Listen to your body and if it goes into the discomfort zone then slow down until you can comfortably do the physical activity that you are trying to do. It won’t be long before your haemo rebounds and then you can push it all you want.

    dt

    5 March 2016 at 2:01 pm #13369
    Avatar photosabrecat
    • Guardian Angel
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    @sabrecat

    “Death and sickness is going to get us in the end, but with a healthier body, the path there will be a little less onerous. And that is certainly worth a lot in itself!”

    Says it all for me too.

    yours

    J.

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