Need advise for gt4 treatment

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13 April 2018 at 3:52 pm #27822
kaju
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@kaju
Hİ Guys,
Today I got my HCV-RNA (real time PCR) result . I cant see the doctor for 1 weeks too so I am wondering maybe you can explain me how is the results.
Thanks.

before treatment: 3.01E+6 IU/ML

After 1 week of treatment: 1.09E+3 IU/mL
13 April 2018 at 6:26 pm #27823
Dr James
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@fixhepc
Your viral load has fallen from 3,010,000 to 1,090 since you started treatment. The E6 says multiply by 1 followd by 6 zeros (1 million) and the E3 multiply by 1 and 3 zeros (1 thousand)

This has fallen at the expected rate.

It would be unusual to be undetected after only on week so things are progressing as expected.

YMMV
13 April 2018 at 8:04 pm #27824
Mar
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@mar
It’s amazing how just 7 pills can have this dramatic effect on the virus count, keep at it Kaju, you’re responding well to the medication

Making the world a better place – one patient at a time.
24 April 2018 at 3:29 pm #27898
kaju
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@kaju
Hi Guys,
Unfortunately today I have bad news.
after 1 month treatment:
ast :171
alt:96
they increased again. Yesterday I did hard sport exercises so I dont knowif it reason the they increased.
also
ldh 1080
I guess I have muscle problem too. hope reason of increasing is muscle so after treatment ıcan focus it
I havent received pcr result I will get it 2 weeks later .
If anybody has any idea I will be greatfull.
Cheers.
25 April 2018 at 5:25 am #27899
Dr James
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@fixhepc
Your ALT and AST should not increase like that.

Do you have Hepatitis B core antibody and Hepatitis B surface antibody results?

YMMV
25 April 2018 at 8:16 am #27900
kaju
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@kaju
Yes, I have. It was negative. I will do another one on friday.
Maybe because of hard exercises.I have muscle pain and ck and ldh very high. Maybe i have myopati. Because one day ago blood test i did exercises and ı has muscle pain.
It happened same few months ago after exercises. Ldh ck alt ast was increased .
Cheers
27 April 2018 at 11:59 am #27913
kaju
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@kaju
Dear Dr James,
I have new test results and
AST dropped to 51 from 171
ALT dropped to 77 from 96. When I looked first week result after treatment ALT was 72.
LDH 186 now, before it was 1080
CK 3000 before 22171
I havent received pcr result of after 1 month treatment.

Regarding to this results I am nervous about to continue treatment? I really needs advise.
I dont know what must I do. If I failed what will be option for me ? Should I wait or should I cut the take pill before treatment resistant increased.
Regards.
27 April 2018 at 1:29 pm #27914
Dr James
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@fixhepc
It is best to continue treatment at full dose for 12 or 24 week duration originally advised by your doctor.

YMMV
27 April 2018 at 1:30 pm #27915
kaju
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@kaju
I just received Hebatitis b results today.

Anti HBC IGG = negative
Anti HBS (Mikropartikül Immün Assay-Meia) = negative
HBSAG = negative

Regards.
30 April 2018 at 12:04 pm #27919
kaju
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@kaju
Dear Mr Dr James,

Today I have another result after 3 days

30.04.2018 27.04.2018 24.04.2018
ast 20 51 171
alt 46 77 96
ck 458 3.328 22.171

I think positive and I hope all is will be better. Can we say all is going pozitive and ast and alt was increased because of hard sit up practise.
Regards.
30 April 2018 at 2:18 pm #27920
Dr James
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@fixhepc
If you get your CK that high after exercise you are doing harm, not good! This looks like muscle damage, not good training…

YMMV
30 April 2018 at 2:28 pm #27921
kaju
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@kaju
Dear Dr James,

Thank you very much for quick response.
I am really gratefull for your help and attention.
Kindest Regards.
7 May 2018 at 10:14 am #27957
kaju
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@kaju
Dear Dr James,

I have new test result.

After 1 month treatment HCV-RNA (real time PCR) is 1.71E+1 IU/mL
1 weeks after start treatment : 1.09E+3 IU/mL

Reference is 12-10-8IU/mL my load is 17 ,1 IU/mL

Can we say treatment is going good ?
Thank you for yur reply from now.
Kindest Regards.
11 May 2018 at 12:12 pm #27999
kaju
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@kaju
Hi Guys,
Are there anybody can give me any comment about my treatment.
I guess my last post was missed.

After 27 days from started treatment my viral load is 17 but it should be less than 12 . I am thinking if I get test end of 28th day maybe copy could be less than 12.
I am very nervous …! Is anybody there who cured after 3 months even not to reach undedected after first 1 month?
Thank you very much for your replys from now.
Cheers.
11 May 2018 at 10:52 pm #28006
Mar
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@mar
Hi Kaju, I’m not a doctor, however in the FAQS page https://fixhepc.com/frequently-asked-questions.html , in the ‘During Treatment’ section, Dr James stated that : “75% of patients who are still detected at the end of treatment, will still go on to SVR12”. So please continue your treatment till you finish all 12 weeks, and only the Viral load test 12 weeks after finishing treatment will show the real result, best of luck.

Making the world a better place – one patient at a time.
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