So here is a song I guarantee none of you have ever head.

It’s called Mr Herbman. It was recorded in the liiving room of my flat. I did the drum intro and some other bits

herbman-2.mp3

hey mr herbman, brew me up some tea
mix your special blend, then share your company
tell me of your life, the secrets of your soul
to me you are a prophet, one who cannot, grow old

mr herbman, your life’s a symphony
mr herbman, your life of harmony
yeah
i wanna know
yeah
i wanna know
(den e said) now you sit and li-sten
for the words here now to grow

mr herbman say

[chorus]
the years they come
the years they pass
slow one now
will later on be fast
it’s a long way up
for a short fall down
gotta keep your eyes wide open
and you feet upon the ground

hear me know
i said this
i said that
mr herbman, yeah

he who’s never travelled
is he who’ll never know
that the start of each new journey
is like start of each new show
every time they listen
every time thay dance
i must say a prayer of thankyou
for being given, the chance

mr herbman, your life’s a symphony
mr herbman, your life of harmony
yeah
i wanna know
yeah
i wanna know
(then e said) now you sit and listen
for the words here now to grow

Either choice Sofosbuvir + Ledipasvir (Harvoni) or Sofosbuvir + Daclatasvir (Sovaldi + Daklinza) is good.

I don’t have a strong preference but suspect Sofosbuvir + Daclatasvir has a slight edge in terms of both SVR and less side effects.

Some patients on Harvoni do seem to go a bit flat and low on energy 6-8 weeks into treatment.

Most of the side effects – headache and insomnia – are caused by Sofosbuvir in the ~ 20% of patients that get them. You have to have that.

Both should see you cured, and because side effects are relatively rare, and very individual it’s often other things that help decide. Daclatasvir mixes well with almost all HIV drugs, and Harvoni is not great for patients with reflux/heartburn taking medication.

Hello AK123,

Congrats on the SVR12. Glad you did 16 weeks – it’s clearly better for GT3s.

With the neuropathy please get checked for diabetes and thyroid function. Some B complex vitamins may well do no good but may help and won’t do any harm.

DAAs don’t cause flu and stopping them does not cure flu.

Stopping them also does not cure Hep C so I would be struggling to see what you think that might achieve.

With your platelets and AST you don’t have cirrhosis. 12 weeks treatment should be fine.

You ALT is normal at SVR12. You will be fine