Never take anything Gilead says at face value. The compassionate access programs are only to get good press, and seem to have been pretty much shut down. They appear to be hindering other entities from providing good information as we’ve seen on online forums and news story comment threads, and they buy the top entries for all relevant search terms which link to their various marketing sites.

They sold the idea that the deals with the Indian companies was about compassion, but in reality they had a good inkling that their patents for sofosbuvir would be rejected and the contracts were really meant to tie the hands of these companies as to where they could market while forcing them to pay royalties for the sales. Companies that didn’t sign on aren’t paying the royalties because the patents were, in fact, rejected in India … as well as in China, with the decision still on hold in Brazil, Russia, and a few others if I understand correctly.

As for access to these drugs in the countries listed, I think I read somewhere that they are available in Honduras now … could be wrong … but remember that each country also has to approve the drugs and then distribution must be worked out before they start actually shipping/stocking the drugs.

It would be helpful if someone who has some time on their hands could research the issue and find out where the drugs are currently available and at what cost.

Here are a couple articles that discuss the issue, but I think both are from before the point that India had made the decision to reject the patents for sofosbuvir.

Gilead’s Hepatitis C Medicines License – Troubling Territorial Exclusions, Illusory Exceptions, and Tiered Pricing Policy Fracture Global Access

(click through to the PDF to read the full article, including the country lists)

http://www.hepcoalition.org/advocate/advocacy-tools/article/gilead-s-license-on-hepatitis-c

Okay, that’s a company I hadn’t seen yet. Sof and Dac available.

http://www.julpharbd.com/

A couple points … first, this guy wasn’t “the inventor,” he was …

Sr. Vice President of Chemistry at Pharmasset, Inc. He joined Pharmasset in 2005 and had responsibility for research strategy, medicinal chemistry, process research, computational chemistry and analytical chemistry functions and was a clinical development project leader. He is an inventor of Sovaldi (sofosbuvir), a treatment of hepatitis C infection currently approved and marketed by Gilead Sciences, Inc.

http://www.oncorebiopharma.com/leadershipteam/

Why he’s given some co-inventor status is a mystery because it looks like he came on board after the drug was developed, but before the trials were completed.

If you’re looking for a person to call “THE inventor” it would be Raymond Schinazi who had left the company before the sale to Gilead
https://en.wikipedia.org/wiki/Raymond_F._Schinazi

… or possibly Jeremy Clark, who actually created the molecule …

In 2002, a young chemist at Pharmasset, called Jeremy Clark, came up with a compound, called PSI-6130, that would bind, very unusually, with the hepatitis C virus in two places at once. Despite PSI-6130 having been licensed to Roche the following year, the much larger company failed to derive a working drug from the molecule, which, several years later, under Schinazi’s guidance at Pharmasset, turned out to be PSI-7977.

http://www.ft.com/cms/s/2/542ad524-8b77-11e2-b1a4-00144feabdc0.html#axzz3lD22Lvzo

Other interesting tidbits.
http://www.reuters.com/article/2011/11/22/us-pharmasset-founder-idUSTRE7AL2ES20111122#YejzQoYggQXmdVWq.97

In any case, I think aiming any anger at those from Pharmasset is misguided. The evil is at Gilead.

None of Schinazi’s companies had any expertise in production, distribution or marketing. Their only expertise was in development. They had no ability talent wise or financially to take the drugs to market and did what any development company does … sell the drug to a marketing company.

Good to hear you’re starting treatment.

Don’t forget to come back and tell us how it’s going.

Hi,

YOU DO NOT WANT INTERFERON.

Can you give specific numbers from your tests? Dr. Freeman will need these to answer your questions.

The critical ones needed to determine treatment are your Genotype and condition of your liver from either a fibroscan or biopsy.

Also helpful are any blood levels that are outside their normal range and information about other meds you’re currently taking or medical conditions such as heart problems.

Here is information to show your doctors.
http://fixhepc.com/kunena-2015-11-10/gp-cheat-sheet.html

Sofosbuvir/Daclatisvir combo is working well across all genotypes, but depending on the condition of your liver you may either need to extend treatment from 12 weeks to 24 weeks and/or add ribavirin to the mix.

If you already have the Sof and Dac you’re almost there!

I had the same thing …. short sleep and then wide awake. It lasted for maybe 10-12 days. I’m getting longer sleep now but still wake up much clearer than before treatment.