Thank you Dr James.I just wish someone like you was supervising my treatment.Unfortunately you live at the opp end of the continent.
I hope you eventually get the peer recognition you deserve for your humantarian efforts.

PKQ.Your post on Simeprevir scares the living daylights out of me.It does not seem to tally with the reported results of trials.But then they are often drug company sponsored.
Is there anyone else out there reading this that has had a similar experience with Simeprevir?

Thank you for this most useful and informative reply Dr James.Could I trouble you for a further opinion?
In fact I can probably go “Gold Standard”
Courtesy of Greg Jefferys and Rachel at Mesochem I have had 3 months supply of Sofosbuvir,Declatasvir,and Ribavirin sitting in the fridge
for 6 weeks now,while I’m shunted between my GP and Specialist with endless delays for appointments.
Simeprevir is available on the PBS,so a triple or quadruple attack is not totally out of the question.
I note in the Impetus 2 trial all partisipants had much higher fibroscan readings,yet a 100% positive result was achieved at 3 months with the triple combination.You mention 24 wks as mandatory in my case but is this dependent on the combination?For 24 wks therapy I will have to try and access another 3mnths supply,which might not still be available if Big Pharma has its way.
I should mention that I am 75yrs old,but not done yet.I recently completed a 600km mountain bike ride with some very steep hills.
Earlier in the year I climbed Mt Agung in Bali,Mt Ranjani in Lombok,and Mt Fansipan in Vietnam.My most tangible problem is knees.