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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17189

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1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17227

Hey GT2! some great posts to go along with your great news eh! :P
... and just so you know, some o' dat mumbo jumbo stuff may help out with that belly of yours ... bet you never thought of this,
"If you ever reach total enlightenment while drinking beer, I bet it makes beer shoot out your nose."
:lol: --- just some more, Deep Thoughts by; Jack Handey :+1:


...just sayi' if it shoots out yer nose, then, VOILA! No beer belly B)
GT1a; Got it some time in the 70's; Diagnosed @1976
Tx naive
METAVIR: A2-F2
SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000
3 weeks after SOT: AST 27 ALT 31 VL 138
Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24
Hep C RNA "NOT DETECTED"
AS OF 3/20/2017 ,Hep C RNA PCR "NOT DETECTED" THAT'S SVR24!
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Last edit: by Matt-Kenney-google.

GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17230

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That cartoon is fab.. Lucky for me my private GP and I took time in our consults to do our 'research ' together...and won. I was his first generics DAA patient it has been fantastic. he always had other junior docs sitting in on consults too, at my approval and delight. :+1: :+1: :+1: :+1: :+1:
Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17231

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Yes it is "fab", GT2! May I re-post it here and there?
Failed Interferon 96', G1a, VL = 9 - 5.5 Million, F3/A3, AST 111, ALT 190, Generic DAA treatment Sof/Led (Mylan - India MYHEP LVIR) - 8 June, 2016
2 Week Results 20 June, 2016 AST 19, ALT 32
4 Week Results 06 July, 2016 AST 22, ALT 30, VL = 35
6 Week Results 20, July 2016 VL only = HCV RNA Detected, Non-Quantifiable <15
8 Week Results 04 August 2016, Labs, LFTs Normal, VL = UND
12 Week Results 31 August, 2016 LFTs Normal, VL = UND
EOT + 4 Weeks, LFTs Normal, VL = UND, "SVR4"
SVR12, 21 Nov 2016. CURED!!!
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17232

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Great news GT2 !
Love the cartoon!!!! :cheer:

Cindi x
J the young dragon slayer is:
HepC 1a since birth
Male aged 15
VL 2000000
Started Twinvir/ 10-11-15-then Sof/led.
NO sides so far !
after one week VL : 37
after 4 wks VL : UND !
EOT 2/2/16 UND.!
4 wks. post tx results....pending....
7/3/16 VL result : 4 week post tx: SVR !
12 weeks SVR !
24 wks SVR yeeaa!!
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17236

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Hi Matt

Thanks for your tip on getting rid of beer bellies.

It’s been quite a few years since I’ve shot beer out of my nose … I’ve had some pretty funny drinking mates over the years and there is nothing better for the soul than when one of them cracks you up while you’re taking a sip of your beer … and VOILA … out it comes … through your nose … yep, there’s nothing better than a true belly laugh and beer shooting out of your nose … it really makes your eyes water … and sooths the soul. These days, however, I’ve been drinking more milk than beer.

1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17237

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Hi Ariel

You are very lucky to have a good GP who puts your health ahead of his/her own self interests. Unfortunately, 6min medicine has become entrenched in this country. Anything that requires a bit of thinking, or ‘research’, is put in the too hard basket and palmed off to someone else (and have to wait months to see) … next patient please … here’s an antibiotic script for your runny nose and another repeat of Ritalin for little Johnny … next patient please …

This is a gross generalisation … there are good GPs out there, but unfortunately they are in the minority. I would like to ask the majority, to look at themselves in the mirror tonight when they are brushing their teeth … and ask themselves, what happened to that bright eyed med student who went around ad nauseam telling everyone how many thousands of patients they were going to cure … well, here’s your chance … and, in the main … you’re asleep at the wheel.
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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Last edit: by GT2.

GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17238

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HI Fitz

You can be The Scarlet Pimpernel … and post it here, and there … you can post it anywhere …

:)

To everyone else, feel free to cut and paste the cartoon and post it anywhere you wish ...
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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Last edit: by GT2.

GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17239

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HI CJ

Glad you liked it … unfortunately, it’s too true … :(
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17240

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GT2 wrote: Hi Ariel

This is a gross generalisation … there are good GPs out there, but unfortunately they are in the minority.


That is why I am on the verge of sacking mine and becoming a GP2U customer
Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17241

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You couldn't do any better than that.
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17253

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Hi GT2
It wasn't always this easy. I wasn't happy for a good while but stuck.
Fortunately I discovered a great GP at my old practice when my old regular GP went on maternity leave, and just coincidentally he started his own practice leaving the old place just around the time I ordered my meds. He also provides pathology inhouse as well as lots of allied health even an audiologist onsite.
He is youngish, caring and has respect for my residual problems re peginf riba and is supportive. He is keen to get people treated who have the virus with DAAs. His staff are kind. The receptionist is happy and polite. I can even book online.
Yes it's definitely quite a find.
I'm sticking with him.
So many people have followed him to his own practice why, because of his excellent duty of care and the extra time he takes.
When I was around week 4 of DAAs I sacked my hospital path and had all my path done privately at the GP. He spent time ringing labs to ensure we had the best assay and PCR tests for me. I really am so very thankful he has gone through this with me.

As an aside did you see James post about thrush, I am certain that is what's going on with my mouth and will pop by my GP for a quick consult and show him the research here.

Cheers from Ariel
Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17260

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Hi Ariel

You have certainly found a good GP. When I grew up, my doctors were like that ... It was a different era.

By far the best doctor I've had is the neurosurgeon who did an emergency operation on me and saved my life ... very, very lucky ... to get the best neurosurgeon at the time who just happened to being doing his ward rounds when the ambulance took me to hospital.

In my initial appointments with him after getting out of hospital, he took the time to get to know what made me tick, got down to my level, and progressively switched my focus from the negative to the positive. He made me feel like his miracle patient who survived against all the odds and, since I’ve made it this far so quickly, there’s nothing stopping me from achieving anything that I wanted … but I had to want to do it. He simply gave me the power of positive thinking.

It worked a treat. When I was in rehab, I witnessed others with less severe injuries than me, with negative attitudes and feeling sorry for themselves, plod along and not seem to make much progress. On the other hand, I was looking forward to my next appointment with my neurosurgeon to tell him about the latest milestone that I had achieved. He used to sit back with a big smile on his face, listen to what I had to say, and then make me feel like I was one in a million & encourage me to keep on pushing myself. Looking back, I realise now that he was the one in a million. I was just one of his patients. :)
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17315

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Hey GT2 :) - great to read your progress reports and thoughts including the comic ones :+1: #love the cartoon says it all doesn't it! I had no local support during Tx and am very thankful that I could contact GP2U at very short notice when I had a question. #flower I live in North East Victoria and just yesterday I read in the local newspaper that 44 scripts had been issued by consultants for the PBS meds. Interesting really cos I wonder how their GP's will provide the support.
gt 1a VL 6m
F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015
sof/dac 10 December for 12 weeks
pre tx alt 85 ast 51
4 wk alt 34 ast 31 UND <35
8 wk alt 29 ast 32 UND <15
12wk alt 25 ast 25 EOT 3.3.16
SVR24 UND KPa5.3 F0 in normal range
I am well
.forever grateful to fixhepc
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Last edit: by pat1.

GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 6 years 5 months ago #17327

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Hi Pat

Copy the above "fixhepc.com" cartoon and send it into your local newspaper with a letter to the editor advising all and sundry that there is excellent support available for the 44 patients available at fixhepc.com. No need to travel to the big smoke or make unnecessary appointments with the local GP (and wait 1hr in the waiting room before he/she sees you). They'll only need to see their GP a couple of times to get some bloods done.

BTW, GPs are in for a rude shock once online consults become medicare rebatable ...

Just being cheeky.

:whistle:

;)
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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