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HCV New Drugs Blogspot 7 years 8 months ago #17631

  • mgalbrai
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This is hell on a phone...


Drug Rationing Plays Russian Roulette With Patients’ Lives
hepatitiscnewdrugs.blogspot.com/2016/06/...an-roulette.html?m=1

2,436 patients with hepatitis C in one Alabama ER since implementing widespread testing in 2013
hepatitiscnewdrugs.blogspot.com/2016/06/...is-c-in-one.html?m=1

Survival rates rise with new hepatitis C treatments
hepatitiscnewdrugs.blogspot.com/2016/06/...w-hepatitis.html?m=1

****4 Week Tx*****
Regulus Reports Positive Data/Phase II studies of RG-101 for the treatment of Hepatitis C
hepatitiscnewdrugs.blogspot.com/2016/06/...ataphase-ii.html?m=1

Foretelling toxicity: FDA researchers work to predict risk of liver injury from drugs
hepatitiscnewdrugs.blogspot.com/2016/05/...researchers.html?m=1

FDA warns against fake Hepatitis C medicines
hepatitiscnewdrugs.blogspot.com/2016/05/...hepatitis-c.html?m=1
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: Chapel, Joy, pat1, Ariel, beaches, Meg, fitz

HCV New Drugs Blogspot 7 years 8 months ago #17800

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Outcomes in patients with chronic Hep C treated with different anti-viral regimens

hepatitiscnewdrugs.blogspot.com/2016/06/...ronic-hep-c.html?m=1
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: DrJames, pat1, Ariel, Gaj, fitz

HCV New Drugs Blogspot 7 years 8 months ago #17943

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Making Hepatitis C A Rare Disease In The United States

hepatitiscnewdrugs.blogspot.ro/2016/06/m...-disease-in.html?m=1
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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: pat1, Ariel, fitz

HCV New Drugs Blogspot 7 years 8 months ago #18444

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A new non-DAA about to commence Phase 1 trials. Looks like it may have potential for 'difficult to treat' cases if proven.

hepatitiscnewdrugs.blogspot.com.au/2016/...f-concept-study.html
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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HCV New Drugs Blogspot 7 years 8 months ago #18446

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mgalbrai wrote: Outcomes in patients with chronic Hep C treated with different anti-viral regimens

hepatitiscnewdrugs.blogspot.com/2016/06/...ronic-hep-c.html?m=1


"Interferon- and ribavirin-containing regimens negatively impact patients’ experience. "
They can pop that in BOLD!
Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
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HCV New Drugs Blogspot 7 years 7 months ago #18586

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Now that we have the hepatitis C virus on the run, can a universal cure be attained?

hepatitiscnewdrugs.blogspot.com/2016/06/...-c-virus-on.html?m=1
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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: pat1, Hazel, fitz

HCV New Drugs Blogspot 7 years 7 months ago #18587

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Thanks Mike. they had a good list of references, but were missing an important one. I added a highlight from latest Liver International journal.
Genotype 3 30 years, 2x treatment interferon/ribavirin non responder. Cirrhosis 17 years. Fibroscan, decompensating, 40 down to 22 by 29/3/16- now down to 6.5, normal, no cirrhosis. Started Buyers Club Sof/Dac 14 Nov 15. SVR 12 29/0716
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HCV New Drugs Blogspot 7 years 7 months ago #18588

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mgalbrai wrote:
hepatitiscnewdrugs.blogspot.com/2016/06/...-c-virus-on.html?m=1


Ty Mike, many interesting studies to read plus
some good coffee news p5

Setiawan and colleagues[16] evaluated the protective effect of coffee drinking in black, Native Hawaiian, Japanese American, Latino, and white patients with chronic liver diseases. Regular coffee intake was associated with reduced risks for NAFLD-related progression in a dose-dependent manner. For example, compared with non–coffee drinkers, those who reported drinking two to three cups and four or more cups of coffee per day had a 14% and a 34% reduction, respectively, in the risk for NAFLD-related disease. High consumption (four or more cups per day of regular coffee) was associated with a reduced risk for HCV-related chronic liver disease.
gt 1a VL 6m
F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015
sof/dac 10 December for 12 weeks
pre tx alt 85 ast 51
4 wk alt 34 ast 31 UND <35
8 wk alt 29 ast 32 UND <15
12wk alt 25 ast 25 EOT 3.3.16
SVR24 UND KPa5.3 F0 in normal range
I am well
.forever grateful to fixhepc
The following user(s) said Thank You: mgalbrai, Ariel, Matt-Kenney-google, fitz

HCV New Drugs Blogspot 7 years 7 months ago #19266

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HCV Guidelines Update: Reflect Recent Approval of Epclusa (Sofosbuvir/Velpatasvir)

hepatitiscnewdrugs.blogspot.com/2016/07/...lect-recent.html?m=1

Velpatasvir/Sofosbuvir Makes HCV Treatment Simpler, Especially For Genotypes 2 and 3

hepatitiscnewdrugs.blogspot.com/2016/07/...r-makes-hcv.html?m=1
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: pat1, Ariel, beaches, fitz

HCV New Drugs Blogspot 7 years 7 months ago #19310

  • mgalbrai
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Gilead's Epclusa® - European Commission Grants Marketing Authorization

hepatitiscnewdrugs.blogspot.com/2016/07/...-commission.html?m=1
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: fitz

HCV New Drugs Blogspot 7 years 7 months ago #19404

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Epclusa among hepatitis drugs that are medical miracles of the 21st century

hepatitiscnewdrugs.blogspot.com/2016/07/...gs-that-are.html?m=1

Hazel Heal!!!

hepatitiscnewdrugs.blogspot.com/2016/07/...ers-club_11.html?m=1

Watch - New Opportunities and Challenges in Hepatitis C

hepatitiscnewdrugs.blogspot.com/2016/07/...-challenges.html?m=1
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: LondonGirl, Gaj, cheese, fitz

HCV New Drugs Blogspot 7 years 7 months ago #19451

  • mgalbrai
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Generic Medications for Hepatitis C


hepatitiscnewdrugs.blogspot.com/2016/07/...hepatitis-c.html?m=1

Hmmmmm...
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: fitz, Sven

HCV New Drugs Blogspot 7 years 7 months ago #19587

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Treatment of Chronic Hepatitis C in the Aged – Does It Impact Life Expectancy? A Decision Analysis

hepatitiscnewdrugs.blogspot.com/2016/07/...atitis-c-in.html?m=1
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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: coral, fitz, Sven

HCV New Drugs Blogspot 7 years 6 months ago #20102

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David Bernstein: Managing Risk Factors in Hepatitis C

hepatitiscnewdrugs.blogspot.com/2016/07/...d-hepatitis.html?m=1

UK health service under fire over access to hepatitis C drugs

hepatitiscnewdrugs.blogspot.com/2016/07/...r-fire-over.html?m=1

New medication shows promise against liver fibrosis in animal studies

hepatitiscnewdrugs.blogspot.com/2016/07/...ise-against.html?m=1


hepatitiscnewdrugs.blogspot.com/2016/07/...aa-regimens.html?m=1

Discovery of new Hepatitis C Virus mechanism

hepatitiscnewdrugs.blogspot.com/2016/07/...tis-c-virus.html?m=1
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: Ariel, fitz

HCV New Drugs Blogspot 7 years 6 months ago #20547

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Elbasvir-grazoprevir works effectively against HCV despite current drug use
hepatitiscnewdrugs.blogspot.com/2016/08/...rks-effectively.html


'Tax haven' Ireland accused of helping US firm treble untaxed profits
hepatitiscnewdrugs.blogspot.com/2016/08/...d-of-helping-us.html


Why are hepatitis C patients treated differently by NHS England?
hepatitiscnewdrugs.blogspot.com/2016/08/...atients-treated.html
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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
The following user(s) said Thank You: DrJames, Ariel, Gaj, fitz
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