TOPIC:

According to my old consultant theSof/INF/ Riba combo is still the best one for Gt3

Hi NADIA,I WAS WONDERING WHICH AREA THE HEPATOLOGIST THAT SAID THEY WOULD MONITOR YOU IS IN AND ALSO IF YOU FOUND A UK DOC THAT WOULD WRITE PRESCRIPTIONS.DAVID

Hi David,
I am being monitored in London. I did not have a script, managed to buy my drugs directly from the suppliers without one.

And your old consultant would be wrong Nadia:

hcvsvrpredictor.liverdoc.com/#/

My old consultant also said the same to me. And the average Joe/Joanne Hepper will believe them. If they could find it in themselves to be honest with us, they would tell us that it's the cheapest treatment for G3 using new meds.

Not sure how accurate this predictor is. The best result for GT3 with cirrosis on Harvoni with riba?
Of course we all know that the NHS budget availability determines the best treatment for us

There's also the latest EASL report, which is available in various threads on here.

What are they saying about Harvoni for GT3? I'm just wondering, is this really the best combo for us?

i have a friend on an NHS trial in Wales that did 12 weeks sof/dac for gt3,prior non responder and cirrhosis.He relapsed 12 weeks after tx and now has to do 24 weeks sof/dac/riba.unfortunately I think interferon combo with sof/riba is still the best for g3.Not certain about this as things are moving so fast..

If the money is not an issue, I think any GT3 with cirrosis should go for 24 weeks with riba first time around. This is the worse type to treat with the new Daas

i had the same conversation with someone else .i thought 24 weeks is best but the other guy said there is no advantage in doing 24.if you are going to clear 12 will do it.all i know is that my friend did 12 and didnt clear.

david wrote: i have a friend on an NHS trial in Wales that did 12 weeks sof/dac for gt3,prior non responder and cirrhosis.He relapsed 12 weeks after tx and now has to do 24 weeks sof/dac/riba.unfortunately I think interferon combo with sof/riba is still the best for g3.Not certain about this as things are moving so fast..

Maybe they didn't know back then what they know now (we'd have to find an older EASL report to find out), but the EASL standard for G3 cirrhotics is 24 weeks Sof/Dac/Riba. The treatment using interferon is sub-optimal, and only used because it's cheaper.

david wrote: i had the same conversation with someone else .i thought 24 weeks is best but the other guy said there is no advantage in doing 24.if you are going to clear 12 will do it.all i know is that my friend did 12 and didnt clear.

That was probably me. Just to make clear: 12 weeks Sof/Dac is for non-cirrhotic/non-borderline G3's.

hi alsdad,yes it was you i had that convo with.the trial my friend is on was very recent.he is still on the 24 week follow up tx.i am sure he would have cleared if they gave him 24 to start with and yes,its very possibly a cost thing with the interferon.it makes me mad that wales nhs have only approved harvoni for 12 weeks when some people clearly would benefit from 24.

I've found and attached the EASL 2014 report. If your friend was treated on a 12 week therapy after the report came out, he should give that clinic a very wide berth.

hi alsdad,it is a very good clinic but he was put on 12 weeks during trials before sof/dac was approved.hopefully it will not happen again as the trial results should now be in.