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Supplements with evidence 7 years 10 months ago #16473

Hi,

My son is continuing with his workouts - he is a fitness instructor - he is taking creatinine as a supplement. Is this ok do you think?

He is wondering if he should drop it or not.

Thank you!

Day 8 of sof led treatment! :-)

Best wishes
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Supplements with evidence 7 years 10 months ago #16474

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It's great to read he is able to keep up such an active life.I got into fitness and it helped me massively. Until my 60 year old back said no to running and other impact cardio

If he's feeling fit now, just imagine how he'll be feeling soon.

I'm kind of thankful I'm not one of his clients :lol:
Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
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Supplements with evidence 7 years 10 months ago #16475

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Creatine is the most studied supplement of all time. It works. There is evidence that some are non responders but most usually are. There is a ton of info out there. Stay away from the fancy stuff that doesn't work and stick to Creatine Monohydrate. 5 to 10g a day. No need to load it. Back in the day they say to take 20g a day for 5 days but new research says no need to.
Genotype 1A
ALT 473
AST 226
Virus Load 3,119,030
Results as of May-2016
5 week viral load/undetected as of 12/02/2016
Liver Biopsy Results from Feb 2013
Portal/Periportal chronic inflammation and mild interface hepatitis (Grade 2)
Focal Lobular chronic inflammation (Grade 1)
Portal/Periportal fibrosis (stage 1-2 trichrome and reticulin stains utilized)
Negative Iron stains.
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Supplements with evidence 7 years 10 months ago #16476

Imagine living with him! :blink:

Supplements with evidence 7 years 10 months ago #16477

Thank you Tommy!

Great advice and he is using just that! Thank you so much!!
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Supplements with evidence 7 years 10 months ago #16478

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Hi Tommy,

Are you aware of any studies of creatine supplementation while on DAA treatment for HCV?
When you refer to non responders is that in reference to HCV treatment while on creatine supplementation?
Can you please provide any links you have to either of these scenarios?
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:

Supplements with evidence 7 years 10 months ago #16479

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I meant non responders to the creatine supplement. The way creatine works shouldn't interfer with hep c meds. It can cause stomach aches, diarrhea, or both in a very small percentage of people. It will most likely cause weight gain to. It pulls water into your muscles, which causes water-weight gain and makes muscles look bigger initially. (You don’t actually gain muscle fibers until you work out.) I would always run anything you take through your doctor. Most recommendations I see from most hep c websites etc say stop taking everything but A multi vitamin mineral supplement and vitamine D when on treatment.
Genotype 1A
ALT 473
AST 226
Virus Load 3,119,030
Results as of May-2016
5 week viral load/undetected as of 12/02/2016
Liver Biopsy Results from Feb 2013
Portal/Periportal chronic inflammation and mild interface hepatitis (Grade 2)
Focal Lobular chronic inflammation (Grade 1)
Portal/Periportal fibrosis (stage 1-2 trichrome and reticulin stains utilized)
Negative Iron stains.
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Supplements with evidence 7 years 10 months ago #16480

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Thanks Tommy. We need to keep in mind that most questions about supplements on this site will be about "when on treatment".

As they are indeed 'supplements' I would suggest erring on the side of caution for the relatively short period of treatment if we don't have supportive evidence. People can take them up again after achieving SVR should they feel there is a benefit for them.
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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Supplements with evidence 7 years 9 months ago #17823

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Hi Everybody,

I've been browsing the threads to see whether I can find good information about the following 2 questions, but I got confused, would anyone have perhaps more information?

1. Vitamin B supplements - before tx I used to take brewer's yeast tablets and I felt quite good. After starting the tx I stopped taking it, because I am not sure if the fungus used to make these tablets might contain bad substances.... 2 weeks ago I took one tablet and in that day I felt slightly better and slept better. So, the question here is if brewer's yeast is safe to take during tx ?

2. Exposure to sun - here in Europe it's sumner time and I would like to spend some days, staying outside, going to the beach, swimming.... During IF+RIB it was not recomnended. How about now, with Sof+Led, no Rib? Will I risk something extra by compare with people not being under treatment? Of course, I will drink plenty of water, using sun cream, etc.

Many thanks,
RHF
In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
HCV kills more than 500000 people every year. HCV generic drugs work. Don't become a statistic.
By sharing this Youtube video you might save someone’s life!
My TX: HEPCVIR-L[generic Harvoni]-India
SVR52 achieved
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Supplements with evidence 7 years 9 months ago #17824

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Hey rohcvfighter
Throughout my 3 month treatment I swam in the ocean at least 4 times a week. It was at 7am, with the occasional swimming later in the day.
I felt fine.
I'll get my EOT results in a bit over a week but expect to be OK
Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
The following user(s) said Thank You: pat1, rohcvfighter, Meg

Supplements with evidence 7 years 9 months ago #17826

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I was on Sof/Dac rather than with Sof/Led so maybe different. I spent several hours at a time in the sun over summer and didn't notice any increased tendency to sunburn but I did make sure I used SPF30+ suncream at all times and didn't spend the full day outside. I did notice my eyes seemed more sensitive to light but a good pair of polarised sunglasses and a hat helped with that.
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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Supplements with evidence 7 years 9 months ago #17828

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Vitamins B and D are good to have during Tx. I swam outside and took Vitamin supplements, Jeunesse AM/PM Essentials (which contains a couple of things recommended not to take with Dac like ginseng but small doses) alternating with Berocca.
I don't imagine brewer's yeast would be a problem but I am not an expert.
Sof/Led is less affected by foods than Sof/Dac, just don't take antacids near the same time as your dose.
M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15.
SVR4 at 7Apr16 ALT 22 AST 22
SVR12 at 9Jun16 ALT 23 AST 25
Melbourne, Australia
The following user(s) said Thank You: pat1, rohcvfighter, Meg

Supplements with evidence 7 years 7 months ago #21001

I completed 8 weeks of tx with Harvoni last Monday. The virus was undetected at 4 weeks and again at 8 weeks. Here are the supplements that I continued to take throughout treatment.

B Complex (methylated form)
Complete Mineral Complex
Omega 3 (fish oil)
Multivitamin (Erewhon store brand)
Vitamin C powder (in my daily health smoothie)
Alpha Lipoic Acid
Probiotics
Now I am also taking Silymarin and Acetyl-L Carnitine. I plan to restart taking CoQ10 and Glutathione, too. All supplements (other than the multivitamin of which I am not certain of) are of high quality.

I also made a daily morning smoothie with:
Almond milk, blueberries, cranberries, apple, fresh ginger, kiwi fruit, banana, avocado, whole raw almonds, flax meal, pumpkin seeds, organic grass fed whey protein.
I have now added kale and barley grass powder to the smoothie since EOT.

Anyway, so many people are worried about supplements during treatment, but I was concerned more about damage from the drug.
Time to heal!
GT 1a
Fibrosis 2
Age 55
Started Harvoni tx 6/21/2016
4 week labs Undetected
EOT 8/15/2016 Undetected
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